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YEAST GENETICS
Determine whether the following yeast genes are linked, and if linked, the map distance between them.
- The haploids leu gly and + + were mated and sporulated.
58 57 21 leu + leu gly leu gly leu + leu gly + gly
- gly + + + +
- gly + + leu +
- The haploids ade gly and + + were mated and sporulated.
7 158 35 ade + ade gly ade gly ade + ade gly + gly
- gly + + + +
- gly + + ade +
- The haploids ade + and + trp were mated and sporulated.
75 3 22 ade + ade trp ade trp ade + ade trp + trp
- trp + + + +
- trp + + ade +
- The haploids his + and + trp were mated and sporulated.
43 42 23 his + his trp his trp his + his trp + trp
- trp + + + +
- trp + + his +
- The haploids his + and + ura were mated and sporulated.
146 8 46 his + his ura his ura his + his ura + ura
- ura + + his +
- ura + + + +
POPULATION GENETICS
For the following questions, assume that the populations are non-ideal. Calculate the allele frequencies. Once you have calculated the allele frequencies, indicate whether the population really is non-ideal or whether it has the Hardy-Weinberg predicted frequencies.
- 2000 AA, 500 Aa. 500 aa
- 400 BB, 600 Bb, 1000 bb
- 2000 CC, 4000 Cc, 2000 cc
- 64000 DD, 32000 Dd, 4000 dd
- 1000 a1a1, 1000 a1a2, 1000 a1a3, 1000 a2a2, 1000 a2a3, 1000 a3a
- 1600 b1b1, 4000 b1b2, 800 b1b3, 2500 b2b2, 1000 b2b3, 100 b3b
Determine the allele frequencies for the following ideal populations where there are two alleles, and the upper case letter is dominant to the lower case.
- A population in which is 60% of the individuals have the A phenotype.
- A population in which is 50% of the individuals have the b phenotype.
- A population in which is 70% of the individuals have the C phenotype.
- A population in which is 84% of the individuals have the D phenotype.
- A population in which is 9% of the individuals have the e phenotype.
- A population in which is 96% of the individuals have the F phenotype.
