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This comprehensive study guide covers fundamental genetics principles, from mendelian inheritance and punnett squares to molecular biology concepts like dna replication and the central dogma. it provides definitions for key terms such as alleles, genotypes, phenotypes, and explores advanced topics including gene linkage, chromosomal mutations, and inheritance patterns. The guide is valuable for students seeking a solid understanding of genetics.
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Gregor Mendel ✔✔a, father of genetics
Genome ✔✔a, the complete genetic material contained in an individual
Genes ✔✔..., sequence of DNA that codes for a protein and thus determines a trait
Mutation ✔✔..., change in a DNA sequence that affects genetic information
Blending Inheritance ✔✔..., each trait of the offspring is a mixture of traits of both parents
Law of segregation ✔✔..., members of a pair of homologous chromosomes separate during the formation of gametes and are distributed to different gametes so that every gamete receives only one member of the pair
P Generation ✔✔..., true-breeding parents
F1 Generation ✔✔..., the first offspring from a cross of two varieties in the parental (P) generation
F2 generation ✔✔..., the offspring from crosses among individuals of the F1 generation
9:3:3:1 ✔✔..., phenotypic ratio of a dihybrid cross
Allele ✔✔..., alternative forms of a gene for each variation of a trait of an organism
Genotype ✔✔..., the particular alleles at specified loci present in an organism
Phenotype ✔✔..., what an organism looks like as a consequence of its genotype
Dominant Trait ✔✔..., the trait observed when at least one dominant allele for a characteristic is inherited
Recessive trait ✔✔..., a trait that is apparent only when two recessive alleles for the same characteristic are inherited,
test cross ✔✔mating of an individual of unknown genotype but dominant phenotype with a homozygous recessive individual
Linked genes ✔✔genes located on the same chromosome that tend to be inherited together in genetic crosses
unlinked genes ✔✔Genes on separate chromosomes that sort out independently of each other.
Locus ✔✔the specific site of a particular gene on its chromosome
Recombination map ✔✔shows how genes closer together are less likely to split apart, related to the effect of the gene at the phenotypic level; show the loci of genes for which mutant alleles (and their mutant phenotypes) have been found
cytological map ✔✔this locates the genes with respect to the chromosomal features, such as stained bands, that can be seen in the microscope
Chromosomes ✔✔threadlike structures made of DNA molecules that contain the genes
Independent assortement ✔✔the random distribution of the pairs of genes on different chromosomes to the gametes
Linkage group ✔✔alleles of different genes that are located on the same chromosome and tend to be inherited together
autosomes ✔✔chromosomes that are not directly involved in determining the sex of an individual
sex chromosomes ✔✔one of the 23 pairs of chromosomes in the human, contains genes that will determine the sex of the individual
N and 2N ✔✔N is the haploid number of chromosomes in an organism. While 2n is the diploid number, the pair of chromosomes in each cell.
Temperature induced (sex determinations?) ✔✔figure this out before exam
Non-disjunctions ✔✔failure of homologous to seperate in Meiosis I or failure of chromatids to seperate in Meiosis II
Inheritance Patterns ✔✔Inheritance patterns trace the transmission of genetically encoded traits, conditions or diseases to offspring
Blood groups ✔✔A, B, AB, O and the Rh factor (+ or -)
Multiple alleles ✔✔the existence of more than two alleles (versions of the gene) for a genetic trait
codominance ✔✔situation in which both alleles of a gene contribute to the phenotype of the organism, a condition in which neither of two alleles of a gene is dominant or recessive, inheritance pattern in which a heterozygote expresses the distinct traits of both alleles
Paternity case ✔✔to do with blood groups figure wtf this means, **** brooks
RH factor ✔✔a blood group antigen possessed by Rh-positive people
, the presence, or lack, of antigens on the surface of red blood cells that may cause a reaction between the blood of the mother and fetus, resulting in fetal anemia
, a marker on Red blood cells that determine whether a person is Rh positive or Rh negative
, Antigen found in red blood cells; used in blood typing.
Incomplete dominance ✔✔one allele is not completely dominant over the other allele
Polygenic inheritance ✔✔occurs when a group of gene pairs acts together and produces a specific trait, such as human eye color, skin color, or height
, An additive effect of two or more genes on a single phenotypic character
epistasis ✔✔a gene at one locus alters the phenotypic expression of a gene at a second locus
Pleitropy ✔✔the control of more than one phenotypic characteristic by a single gene
, A single gene affects more than one trait
DNA ✔✔(biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix
RNA ✔✔(biochemistry) a long linear polymer of nucleotides found in the nucleus but mainly in the cytoplasm of a cell where it is associated with microsomes
DNA VS RNA ✔✔RNA contains ribose instead of deoxyribose, RNA contains uracil instead of thymine like DNA, RNA is single-stranded rather than double-stranded like DNA, RNA is smaller than DNA
Chargaff's rule ✔✔Equal amounts of adenine bonds with thymine and equal amount of guanine bonds with cytosine.
, [A]=[T] and [G]=[C], they pair up across from one another forming two strands also called base pairing.
Waston and Crick ✔✔Developed the current model for the DNA double helix; determine the structure of DNA
5 end 3 end ✔✔ask becca
Central Dogma ✔✔theory that states that, in cells, information only flows from DNA to RNA to proteins
replication ✔✔(genetics) the process whereby DNA makes a copy of itself before cell division
transcription ✔✔DNA serves as a template for RNA
process by which a DNA template is used to produce a single-stranded RNA molecule
translation ✔✔(genetics) the process whereby genetic information coded in messenger RNA directs the formation of a specific protein at a ribosome in the cytoplasm
retroviruses ✔✔viruses that contain RNA as their genetic information
Helicase ✔✔an enzyme that untwists the double helix at the replication forks, separating the two parental strands and making them available as template strands
RNA splicing ✔✔process by which the introns are removed from RNA transcripts and the remaining exons are joined together
Intron ✔✔Long segments of nucleotides that have no coding information
exon ✔✔expressed sequence of DNA; codes for a protein, coding region in RNA transcript, sequence of a gene's DNA that transcribes into protein structures
DNA>RNA>Protein ✔✔central dogma, RNA determined by dna, protein determined by rna
Genetic Code ✔✔the ordering of nucleotides in DNA molecules that carries the genetic information in living cells, NEARLY UNIVERSAL
Codons ✔✔A three-nucleotide sequence of DNA or mRNA that specifies a particular amino acid or termination signal; the basic unit of the genetic code.
amino acid ✔✔basic building blocks of protein molecules
Nucleotide ✔✔The building block of a nucleic acid, consisting of a five-carbon sugar covalently bonded to a nitrogenous base and a phosphate group.
ribosomal rna ✔✔type of RNA that makes up the major part of ribosomes, rRNA
Peptide bond ✔✔the primary linkage of all protein structures, covalent bond formed between amino acids, A bond that links amino acids together in a protein
Transfer RNA ✔✔short-chain RNA molecules present in the cell (in at least 20 varieties, each variety capable of combining with a specific amino acid) that attach the correct amino acid to the protein chain that is being synthesized at the ribosome of the cell
, type of RNA molecule that transfers amino acids to ribosomes during protein synthesis
Anti-Codons ✔✔Three-base sequence in a transfer RNA molecule base that pairs with a complementary codon in mRNA
Anti-codons vs codons ✔✔??