Docsity
Docsity

Prepare for your exams
Prepare for your exams

Study with the several resources on Docsity


Earn points to download
Earn points to download

Earn points by helping other students or get them with a premium plan


Guidelines and tips
Guidelines and tips

Sympathomimetic Drugs and Receptors: A Comprehensive Guide, Quizzes of Pharmacology

An in-depth exploration of sympathomimetic drugs, their definitions, receptors, effects, and specific examples. Topics covered include vasoconstrictors, b1 and b2 receptors, ultra-short acting catecholamines, epinephrine, isoproterenol, isoetharine, short acting noncatecholamines, metaproterenol, terbutaline, albuterol, bitolterol, pirbuterol, long-lasting bronchodilators, salmeterol, formoterol, arformoterol, advair, symbicort, dulera, omalizumab, sympathomimetic side effects, sympathomimetic contraindications, common inhaled steroids, common leukotriene modifiers, parasympatholytics, atropine, ipratropium bromide, tiotropium bromide, parasympatholytics contraindications/side effects, and corticosteroids.

Typology: Quizzes

2013/2014

Uploaded on 08/29/2014

patriciapoulin
patriciapoulin 🇺🇸

1 document

1 / 8

Toggle sidebar

This page cannot be seen from the preview

Don't miss anything!

bg1
TERM 1
Sympathomimetic
DEFINITION 1
Sympathomimetic drugs mimic the effects of transmitter
substances of the sympathetic nervous system such as
catecholamines, epinephrine, norepinephrine
(noradrenaline), dopamine, etc. Stimulate Adenyl Cyclase,
increase cyclic adenosine monophosphate (cAMP)
TERM 2
A Receptor
DEFINITION 2
Vasoconstrictor, increases blood pressure
TERM 3
B1 Receptor
DEFINITION 3
Increase HR and contractility
TERM 4
B2 Receptor
DEFINITION 4
Bronchodilation
TERM 5
Ultra Short Acting Catecholamines
DEFINITION 5
All lack specific B2 activity. Cause tachycardia, increases
blood pressure, short duration, and fast onset
pf3
pf4
pf5
pf8

Partial preview of the text

Download Sympathomimetic Drugs and Receptors: A Comprehensive Guide and more Quizzes Pharmacology in PDF only on Docsity!

Sympathomimetic

Sympathomimetic drugs mimic the effects of transmitter substances of the sympathetic nervous system such as catecholamines, epinephrine, norepinephrine (noradrenaline), dopamine, etc. Stimulate Adenyl Cyclase, increase cyclic adenosine monophosphate (cAMP) TERM 2

A Receptor

DEFINITION 2 Vasoconstrictor, increases blood pressure TERM 3

B1 Receptor

DEFINITION 3 Increase HR and contractility TERM 4

B2 Receptor

DEFINITION 4 Bronchodilation TERM 5

Ultra Short Acting Catecholamines

DEFINITION 5 All lack specific B2 activity. Cause tachycardia, increases blood pressure, short duration, and fast onset

Epinephrine

Racemic Epinephrine - MicroNefrin, VapoNefrinA and B receptor sitesSVN 0.25-0.5 mlOnset 3-5 minutesDuration 0.5- 2 or 3 hours TERM 7

Isoproterenol

DEFINITION 7 Isuprel (Major cardiac effect)B receptor site (more B1)SVN 0.25-0.5 ml or 1.25 - 2.5 mgOnset 2-5 minutesDuration 0.5- hoursRarely used today TERM 8

Isoetharine

DEFINITION 8 IsoeatharineB receptor site (B1)SVN 0.25-0.5 ml or 1.25-2. mgOnset 1-6 minutesDuration 15-60 minutesRarely used today TERM 9

Short Acting Noncatecholamines

DEFINITION 9 Longer acting B2 specificDuration 4-6 hours TERM 10

Metaproterenol

DEFINITION 10 AlupentSVN 0.2-0.3 ml or 4% or 6%Onset 1- minutesDuration 2-6 hours

Long Lasting Bronchodilators

Slower onset of action (20-30 minutes)B2 receptor sitesMaintenance and nocturnal controlOften combined with anti-inflammatory agents TERM 17

Salmetrol

DEFINITION 17 SereventSalmeterol is a long-acting beta2-adrenergic receptor agonist drug that is prescribed for the treatment of asthma and chronic obstructive pulmonary disease. MDI 25mcg/puff - 2 puffs BIDDPI 50mcg/puff - 1 puff BIDOnset 20 minutes Duration 12 hours TERM 18

Formoterol

DEFINITION 18 ForadilFormoterol or eformoterol (former BAN) is a long- acting 2 agonist used in the management of asthma and chronic obstructive pulmonary disease (COPD). DPI 12mcg/inhalation BID (higher doses can cause bronchospasm)Onset 5 minutesDuration 12 hoursMust be refrigerated TERM 19

Brovana

DEFINITION 19 Arformoterol 15mcg/2mlTwice dailyNebulizer onlyTreatment of COPDDo not take other LABAEmergency use only TERM 20

Advair

DEFINITION 20 The combination preparation fluticasone/salmeterol is a formulation containing fluticasone propionate and salmeterol xinafoate, used in the management of asthma and chronic obstructive pulmonary disease. Flovent and Serevent

Symbicort

Budesonide/formoterol is a combination formulation containing budesonide and formoterol used in the management of asthma and chronic obstructive pulmonary disease in the EU. Pulmicort and Foradil TERM 22

Dulera

DEFINITION 22 Mometasone/formoterol is a combination inhaler containing both an inhaled corticosteroid and long acting bronchodilator. Anti-fungal steroid TERM 23

Omalizumab

DEFINITION 23 Omalizumab is a humanized antibody originally designed to reduce sensitivity to inhaled or ingested allergens, especially in the control of moderate to severe allergic asthma, which does not respond to high doses of corticosteroids. XolairSteroid freeInjection 1x month TERM 24

Sympathomimetic Side Effects

DEFINITION 24 TremorsTachycardiaNauseaHeadachePalpitationsHypertensionRe TERM 25

Sympathomimetic

Contraindications

DEFINITION 25 HyperthyroidismHypertensionTachycardiaTolerance (tachyphylaxis)

Tiotropium Bromide

SpirivaTiotropium bromide is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Once daily dosingSlow onset (30 min)Significant FEV increase1st line COPD TERM 32

Parasympatholytics Contraindications/Side

Effects

DEFINITION 32 Narrow angle glaucoma Nervousness TachycardiaVertigoPalpitations NauseaGI DistressDry MouthThick secretions TERM 33

Corticosteroids

DEFINITION 33 Controls airway inflammation without systemic side effectsEnhance B2 bronchodilatorsMaintenance and use in exacerbationsEffects take hours to days TERM 34

Dexamethasone

DEFINITION 34 DecadronDexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs that has anti- inflammatory and immunosuppressant effects. MDI TERM 35

Beclomethasone

DEFINITION 35 QVAR, Vanceril, Beclovent Not for Oral useMDI 42mcg

Triamcinolone Acetonide

Azmacort Low systemic absorptionBuilt in spacerMDI 100mcg TERM 37

Flunisolide

DEFINITION 37 AerobidFlunisolide is a corticosteroid often prescribed as treatment for allergic rhinitis. MDI TERM 38

Budesonide

DEFINITION 38 Budesonide is a glucocorticoid steroid for the treatment of asthma, COPD and non-infectious rhinitis, and for treatment and prevention of nasal polyposis. MDI - Pulmicort Plasma 1/2 life, 2 hoursDPI 200 mcg