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Anatomy and Physiology of the Tongue: Papillae, Taste Buds, and Diseases, Slides of Medicine

An in-depth exploration of the tongue's structure, focusing on papillae types, their functions, and the taste buds. It covers filiform, fungiform, and circumvallate papillae, their filaggrins, nerve supply, and functions. The document also discusses diseases and conditions affecting the tongue, such as lichen planus, amyloidosis, and granular cell tumors.

What you will learn

  • What are the functions of filiform papillae on the tongue?
  • What are the different types of papillae on the tongue and where are they located?
  • What are the main causes and symptoms of lichen planus?
  • What are the different types of amyloidosis and how are they diagnosed?
  • How do taste buds in the tongue work?

Typology: Slides

2021/2022

Uploaded on 09/12/2022

leonpan
leonpan 🇺🇸

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The Dorsal Tongue
Cancer and Other Maladies
James J. Sciubba, DMD, PhD
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Download Anatomy and Physiology of the Tongue: Papillae, Taste Buds, and Diseases and more Slides Medicine in PDF only on Docsity!

The Dorsal Tongue

Cancer and Other Maladies

James J. Sciubba, DMD, PhD

The Basics Form and Structure

  • The tongue surface
    • Filiform papillae
    • Fungiform papillae
    • Vallate papillae
    • Foliate papillae

Filiform Papillae

H: hair-like S: skin- like LM: lining mucosa- like

Filiform Papillae

Anterior compartment

  • Hair-like pattern of keratin differentiation
    • Keratin expression: K 4, 6, 13, 16 & KHG proteins

Posterior compartment

  • Skin-like keratin differentiation pattern 1, 10

Intervening area / between compartments

  • Resembles lining / buccal mucosa

Filiform Papillae Further Characteristics

  • Epithelial cells contain keratin-bundling proteins
    • Filaggrins
      • Co-localize with trichohyalin protein
      • Crucial in the keratinization process
  • Nerve supply
    • Three types of nerve endings
      • Free unmyelinated-extend to subepithelial CT
      • Epithelial nerve endings-near BMZ or within basal / suprabasal cells
      • Complex nerve endings-lamellar corpuscles: sensory mechanoreceptors - Spatial perception: magnified by a factor of 1:

Foliate Papillae

  • At posterolateral location
  • Deeply folded mucosa
  • Cornified surface
  • Lymphoid stroma deep to surface
  • Numerous taste buds along lateral walls early in life
    • Atrophy later in life

Circumvallate Papillae

  • 2.5 mm wide-1.0 mm deep
  • Richly innervated and vascularized
  • Each papilla is trenched
    • flushed by von Ebner glands
      • Up to 35 ducts rim the base of each papilla
  • Lateral surfaces w/ hundreds

of taste buds

The Taste Bud A Bioengineering Marvel

Taste Bud Facts

  • III: contain “densities” and synaptic vesicles - vesicles contact nerve endings - Similar to type II cells
  • IV: small basal cells
    • Differentiate into other taste bud cells
  • V: perigemmal cells
    • At taste bud periphery
    • Contain perigemmal nerve endings

The Lingual Follicle

  • In aggregate form the lingual tonsil
  • Are small lymphoepithelial organs
  • Contain mucous glands opening into crypts (Cr)
  • Lining is non-keratinizing

Capsule

Plate: I II III IV

Intemperance

Dental Indentations

Idiopathic Excoriations

Tertiary Syphilis

Tertiary Syphilis

Chronic Ulcer

Dental Trauma

TB

Lupus

Mucous Patch

Gummatous Ulcer

Ruptured Gumma