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Material Type: Exam; Class: Developmental Bio-HON; Subject: Biological Sciences; University: Wayne State University; Term: Winter 2016;
Typology: Exams
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Name___________________________________ Date________________________
MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question. Questions 1 - 34 are each worth 2.5 points. Question 35 is worth 3.5 points.
A) Mutant I will have no fingers, whereas mutant II will have extra fingers B) Mutant I will have extra fingers, whereas mutant II will have no fingers C) Both mutant I and mutant II will have extra fingers D) Both mutant I and mutant II will have no fingers E) Both mutants will have a wild-type number of fingers
A) are loose, unconnected cells that can migrate B) can arise from the mesoderm C) can arise from the ectoderm D) Two of the above E) All of the above
A) Gene A and gene B act antagonistic of each other B) Gene A and gene C act antagonistic of each other C) Gene B and gene C act non-antagonistic of each other D) Gene A and gene C act non-antagonistic of each other E) Two of the above
A) A human embryo B) A C. elegans embryo C) Cells at the two-cell stage are not totipotent D) Two of the above E) All of the above
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A) Fertilization can occur between wild type and mutant I or between wild type and mutant II B) Fertilization can occur between mutant I and mutant II, leading to a new species C) All of the above D) None of the above
A) A Smoothened (Smo) loss-of-function mutation leads to a naked embryo B) A GSK3 gain-of-function hypermorphic mutation leads to a naked embryo C) A Frizzled (Fz) loss-of-function mutation leads to a hairy embryo D) A Patched (Ptc) loss-of-function mutation leads to a hairy embryo E) None of the above
A) A Smoothened (Smo) loss-of-function mutation leads to a vertebrate with extra limbs B) A GSK3 gain-of-function hypermorphic mutation leads to a vertebrate with extra limbs C) A Frizzled (Fz) gain-of-function hypermorphic mutation leads to a limbless vertebrate D) A Patched (Ptc) loss-of-function mutation leads to a limbless vertebrate E) None of the above
A) The guanosine will become methylated B) All cytosines will become methylated C) Only the cytosine 5 ʹ of the guanosine will become methylated D) The promoter will become demethylated
A) Both parental copies of the gene will be expressed B) Both parental copies of the gene will not be expressed C) Only the maternal copy of the gene will be expressed D) Only the paternal copy of the gene will be expressed
Name___________________________________ Date________________________
Name___________________________________ Date________________________
A) stimulates the cell to enter mitosis from G2 during the cell cycle B) stimulates the oocyte to continue through meiosis C) consists of a cyclin and a cyclin-dependent kinase D) Two of the above E) All of the above
A) can occur in the developing vertebrate embryo or in the adult B) only occurs in the developing vertebrate embryo C) only occurs in the vertebrate adult D) does not occur in vertebrates
A) In vertebrates, the digestive system and musculoskeletal system arise from the endoderm B) In vertebrates, the digestive system arises from the endoderm, whereas the musculoskeletal system arises from the ectoderm C) In vertebrates, the digestive system arises from the endoderm, whereas the musculoskeletal system arises from the mesoderm D) In vertebrates, the digestive system and the musculoskeletal system arise from the mesoderm E) None of the above
A) is determined by the site of sperm entry during fertilization B) involves the dorsal enrichment of GSK3 during the blastula stage C) involves the cortical rotation of the egg cytoplasm during the gastrula stage D) None of the above
A) Segregation B) Independent Assortment C) All of the above D) None of the above
A) Activation of the Ci transcription factor ( Drosophila Gli) has no effect on its subcellular localization B) Activation of the Ci transcription factor ( Drosophila Gli) causes it to shuttle from the nucleus to the cytoplasm C) Activation of the Ci transcription factor ( Drosophila Gli) causes it to shuttle from the cytoplasm to the nucleus D) None of the above
Name___________________________________ Date________________________
A) the A and Aʹ axis B) the B and Bʹ axis C) the C and Cʹ axis D) Two of the above E) All of the above
A) Gene T is epistatic to both gene R and gene S B) Gene S is epistatic to both gene R and gene T C) Gene R is epistatic to both gene S and gene T
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SHORT ANSWERS. Write your answers within the space provided.
From the information given in question 35, draw a possible pathway that would best depict the interactions between genes R, S and T, if they are acting within a linear pathway. (4 points)
What is the difference between an instructive inductive signal and a permissive inductive signal? (2.5 points) Name an example for each type of signal. (2 points)