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Syllabus of VTU biotechnology Belagum and its a 2018 scheme
Typology: Schemes and Mind Maps
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18BT46 Clinical Biochemistry syllabus Module- METABOLISM OF CARBOHYDRATES AND LIPIDS: Glycolysis–metabolism. Aerobic and anaerobic pathway and regulation, TCA cycle, NADPH Cycle, Glyoxylate cycle, Pentose Phosphate Pathway. Electron transport chain and oxidative phosphorylation, energy balance sheet. Gluconeogenesis – regulation of gluconeogenesis. Biosynthesis of polysaccharides. Biosynthesis of fatty acids, cholesterol, phospholipids, glycolipids. Biodegradation of triglycerides and fatty acids. Module- DISORDERS OF CARBOHYDRATE METABOLISM: Diabetes mellitus, glycohemoglobin, hypo-glycaemia, galactosemia and ketone bodies. Various types of glucose tolerance tests. Glycogen storage diseases. Physiology of lipids/lipoproteins. Lipidosis. Clinical interrelationships of lipids (sphingolipidosis and multiple sclerosis), lipoproteins and apolipoproteins. Diagnostic tests for HDL-cholesterol, LDL-cholesterol and triglyceride disorders. Module- METABOLISM OF AMINO ACIDS AND NUCLEIC ACIDS: Biosynthesis and catabolism of essential amino acids: Lysine, Phenylalanine and Glutamine. Deamination, transamination and urea cycle. Metabolism and regulation of Purines, pyrimidine and precursors of nucleic acids (nucleosides & nucleotides). Module- DISORDERS OF AMINO ACIDS AND NUCLEIC ACIDS METABOLISM AND HORMONAL DISTURBANCES: a) Disorders of amino acid metabolism - Phenylalanemia, homocystinuria, tyrosinemia, MSUD, phenylketonuria, alkaptonuria, albinism and aminoaciduria. b) Disorders of nucleic acid metabolism- Disorders in purine/ pyrimidine metabolism. c) Protein hormones (anterior pituitary hormones, posterior pituitary hormones), steroid hormones, adrenocorticosteroids, and reproductive endocrinology. Disturbances in thyroid function. Module- DISORDERS OF ACID-BASE BALANCE AND THEIR RESPIRATORY AND RENAL MECHANISMS: Evaluation of organ function tests, Assessment and clinical manifestations of renal, hepatic, pancreatic, gastric and intestinal functions. Clinical importance of bilirubin. Diagnostic enzymes: Principles of diagnostic enzymology. Clinical significance of aspartate aminotransferase, alanine aminotransferase, creatine kinase, aldolase and lactate dehydrogenase. Enzyme tests in determination of myocardial infarction. Enzymes of pancreatic origin and biliary tract.