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Riboswitches - Biotechnology - Exam, Exams of Biotechnology

Punjab Agricultural UniversityBiotechnology

Riboswitches, Elaborate Secondary Structure, Obesity, Specific Mutation, Antigen Presenting Cell, Immunological Synapse, Distinct Cell Types, Three Protein Targets, Sirtuin Family Member, Alzheimers Disease are some points from questions.

Typology: Exams

2011/2012

Uploaded on 11/30/2012

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NATIONAL UNIVERSITY OF IRELAND, GALWAY
Ollscoil na hÉireann, Gaillimh
SUMMER EXAMINMATIONS 2008
Exam Code(s) 2BY121
Exam(s) Denominated degree in Biotechnology
Module Code(s) BG202
Module(s) Biotechnology II
Paper No. 2
External Examiner(s) Dr. Paul McLaughlin
Internal Examiner(s) Dr. P. Creighton, Dr. J. Donlon, Dr. A. Flaus,
Prof. B. Lahue, Dr. C. Morrison, Dr. J. O’Keeffe,
Prof. K. Sullivan, Dr. M. Tuohy
Instructions: SECTION A
Answer six out of nine questions.
Write on the examination paper
SECTION B
Answer two out of nine questions
Duration TWO hours
Number of pages Four
Department(s) Biochemistry
Course Co-ordinator Dr. Joan O’Keeffe
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NATIONAL UNIVERSITY OF IRELAND, GALWAY

Ollscoil na hÉireann, Gaillimh SUMMER EXAMINMATIONS 2008 Exam Code(s) 2BY Exam(s) Denominated degree in Biotechnology Module Code(s) BG Module(s) Biotechnology II Paper No. 2 External Examiner(s) Dr. Paul McLaughlin Internal Examiner(s) Dr. P. Creighton, Dr. J. Donlon, Dr. A. Flaus, Prof. B. Lahue, Dr. C. Morrison, Dr. J. O’Keeffe, Prof. K. Sullivan, Dr. M. Tuohy Instructions: SECTION A Answer six out of nine questions. Write on the examination paper SECTION B Answer two out of nine questions Duration TWO hours Number of pages Four Department(s) Biochemistry Course Co-ordinator Dr. Joan O’Keeffe

SECTION A (Answer six questions) Name: ________________________________ Student ID Number: _ ________________________________

  1. Riboswitches are RNA molecules with an elaborate secondary structure. Why does DNA not form such structures?
  1. What is obesity?
  1. Give an example of a drug and its target which have been designed against a specific mutation.
  1. What is the role of the Antigen Presenting Cell in the formation of the immunological synapse?
  1. Most organs arise from interactions between two distinct cell types, _____________________________and________________________________________

SECTION B (Answer two questions)

  1. Describe how alternative splicing can give rise to multiple protein species from the same DNA sequence template.
  2. Write an essay on the development and progression of atherosclerosis.
  3. Explain why it has been claimed that large scale genomic investigation may be the most efficient way to identify factors involved in cancer. or Explain the principle of ‘sequencing by synthesis’ using examples of technologies under development for low cost genome sequencing.
  4. Describe what the Toll-like receptors are and discuss their function in immunity.
  5. ‘The body has a significant capacity for regeneration following tissue damage’. Discuss this statement.
  6. Darwin’s theory addressed the origin of the species, but we now know that evolution occurs at every level of biological organization and tissues, cells and molecular networks all represent environments with niches where selective advantage can be expressed. Discuss how chromosome instability contributes to the evolution of tumour cells adapted for life within a tumour. or Explain how cytokines promote tumour formation and the cells that contribute to this pathway.
  7. Give an account of genes which regulate the lifespan of an organism.
  8. Discuss the statement, “Abnormal and dysfunctional blood vessels are a hallmark of solid tumours”
  9. ‘Proteins play key roles in neurological diseases, such as Alzheimer’s disease or Parkinson’s disease’. Discuss this statement with reference to one or other disease.