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An in-depth analysis of contrast media induced nephropathy (cmin), the third leading cause of hospital-acquired acute renal failure. It covers the pathogenesis, risk factors, and treatment options for this condition. The document also discusses the role of radiocontrast agents in nephropathy and the preventive measures that can be taken.
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Baseline renal insufficiency
DM
CHF
Large volume of contrast NSAIDs or ACEI
Volume depletion
ARF:increase in serum creat of>50 % above baseline or >1 mg/dl if baseline>2 mg/dl
Extracorporeal blood purification therapies for prevention of radiocontrast-induced nephropathy: a systematicreview. Am J Kidney Dis 2006; 48:361. Renal protection for coronary angiography in advanced renal failure patients by prophylactic hemodialysis. Arandomized controlled trial. J Am Coll Cardiol 2007; 50:1015.
Heme pigment-induced acute tubular necrosis
The majority of cases of rhabdomyolysis are nontraumatic
Alcohol abuse
Massive muscle compression from immobilization in drug induced coma
Drug-induced
Seizures
Occlusive peripheral vascular disease.
Combination therapy with itraconazole, simvastatin, and cyclosporine Conversion from one fibric acid to another, or from one statin-fibrate combination to another Detergent ingestion