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Quiz 3 with Answer Key - Developmental Biology Honors | BIO 5620, Quizzes of Developmental biology

Wayne State University (WSU)Developmental biology

Material Type: Quiz; Class: Developmental Bio-HON; Subject: Biological Sciences; University: Wayne State University; Term: Winter 2016;

Typology: Quizzes

2015/2016

Uploaded on 04/05/2016

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Quiz3
Name__________________________________ Date___________________
MULTIPLECHOICE.Choosetheonealternativethatbestcompletesthestatementoranswersthequestion.Questions
areeachworth2.5points.(Total=12.5points)
1) Anembryocarriesagain-of-functionhypermorphicmutationinFrizzled,wheretheproteinis
alwaysactiveintheroofplatecells.Thesameembryocarriesaloss-of-functionmutationin
-catenin,butonlyinthedorsalcellsofthesomiticmesoderm.Whichofthefollowingwillmost
likelyhappen?
A) Theembryowilldevelopmoretrunkmuscles
B) Theembryowillhaveanexpandeddermomyotome
C) Theembryowillhavefewertrunkmuscles
D) Theembryowillbenormal
E) Noneoftheabove
1)
2) AneuralcrestcellisattractedtobodycompartmentX.Whichstatementbelowmightbetrue?
A) TheneuralcrestcellmayexpressPlexinA2andthecellsinbodycompartmentXmay
expressSemaphorin6A
B) TheneuralcrestcellmayexpressanEphreceptorthathasweakinteractionswithanephrin
expressedinthecellsofbodycompartmentX
C) TheneuralcrestcellmayexpressPlexinA2thathasstronginteractionswithanephrin
expressedinthecellsofbodycompartmentX
D) Twooftheabove
E) Alloftheabove
F) Noneoftheabove
2)
3) AneuralcrestcellisrepelledfrombodycompartmentY.Whichstatementbelowmightbetrue?
A) TheneuralcrestcellmayexpressPlexinA2andthecellsinbodycompartmentYmay
expressSemaphorin6A
B) TheneuralcrestcellmayexpressanEphreceptorthathasweakinteractionswithanephrin
expressedinthecellsofbodycompartmentY
C) TheneuralcrestcellmayexpressPlexinA2thathasstronginteractionswithanephrin
expressedinthecellsofbodycompartmentY
D) Twooftheabove
E) Alloftheabove
F) Noneoftheabove
3)
1
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Download Quiz 3 with Answer Key - Developmental Biology Honors | BIO 5620 and more Quizzes Developmental biology in PDF only on Docsity!

Quiz 3

Name__________________________________ Date___________________

MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question. Questions are each worth 2.5 points. (Total = 12.5 points)

  1. An embryo carries a gain-of-function hypermorphic mutation in Frizzled, where the protein is always active in the roof plate cells. The same embryo carries a loss-of-function mutation in -catenin, but only in the dorsal cells of the somitic mesoderm. Which of the following will most likely happen?

A) The embryo will develop more trunk muscles B) The embryo will have an expanded dermomyotome C) The embryo will have fewer trunk muscles D) The embryo will be normal E) None of the above

  1. A neural crest cell is attracted to body compartment X. Which statement below might be true? A) The neural crest cell may express Plexin A2 and the cells in body compartment X may express Semaphorin 6A B) The neural crest cell may express an Eph receptor that has weak interactions with an ephrin expressed in the cells of body compartment X C) The neural crest cell may express Plexin A2 that has strong interactions with an ephrin expressed in the cells of body compartment X D) Two of the above E) All of the above F) None of the above
  1. A neural crest cell is repelled from body compartment Y. Which statement below might be true? A) The neural crest cell may express Plexin A2 and the cells in body compartment Y may express Semaphorin 6A B) The neural crest cell may express an Eph receptor that has weak interactions with an ephrin expressed in the cells of body compartment Y C) The neural crest cell may express Plexin A2 that has strong interactions with an ephrin expressed in the cells of body compartment Y D) Two of the above E) All of the above F) None of the above

Quiz 3

Name__________________________________ Date__________________

  1. Unlike person I, person II below has mirror image digit duplication. Which conclusion below is likely true?

A) Person I has a gain-of-function mutation in Patched, where it is always active in both anterior and posterior parts of his limb during development B) Person II has a gain-of-function mutation in Patched, where it is always active in both anterior and posterior parts of his limb during development C) Person I has a loss-of-function mutation in Gli D) Person II has a loss-of-function mutation in Gli E) None of the above

  1. The chick limb on the left is normal, whereas the limb on right is the result of a grafting experiment, where proximal structures are missing. This post-grafting phenotype is likely due to:

A) very high levels of FGF in the grafted tissue, which leads to activation of the distal-most specific Hox gene, activation of Gremlin and termination of limb outgrowth B) very high levels of FGF in the grafted tissue, which leads to activation of the distal-most specific Hox gene, inhibition of Gremlin and termination of limb outgrowth C) very low levels of FGF in the grafted tissue, which leads to activation of the distal - most specific Hox gene, activation of Gremlin and termination of limb outgrowth D) very low levels of FGF in the grafted tissue, which leads to activation of the distal - most specific Hox gene, inhibtion of Gremlin and termination of limb outgrowth