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Quiz#3 | MICB 4131 - Immunology, Quizzes of Immunology

Class: MICB 4131 - Immunology; Subject: Microbiology; University: University of Minnesota - Twin Cities; Term: Fall 2011;

Typology: Quizzes

2010/2011

Uploaded on 11/11/2011

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TERM 1
Lck
DEFINITION 1
a tyrosine kinase, which phosphorylates tyrosine residues of
certain proteins involved in the intracellular signaling
pathways of these lymphocytes.
TERM 2
CD45
DEFINITION 2
Protein tyrosine phosphatase, receptor type, C also known as
PTPRC is an enzyme that, in humans, is encoded by the
PTPRC gene.
TERM 3
ZAP-70
DEFINITION 3
ZAP-70 is an abbreviation for Zeta-chain-associated protein
kinase 70 (70 is the molecular weight in kDa).
TERM 4
DAG, IP3
DEFINITION 4
Second messengers
TERM 5
CD3
DEFINITION 5
In immunology, the ------T-Cell Co-Receptor (CD stands for
cluster of differentiation) is a protein complex and is
composed of four distinct chains.
pf3
pf4

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Lck

a tyrosine kinase, which phosphorylates tyrosine residues of certain proteins involved in the intracellular signaling pathways of these lymphocytes. TERM 2

CD

DEFINITION 2 Protein tyrosine phosphatase, receptor type, C also known as PTPRC is an enzyme that, in humans, is encoded by the PTPRC gene. TERM 3

ZAP-

DEFINITION 3 ZAP-70 is an abbreviation for Zeta-chain-associated protein kinase 70 (70 is the molecular weight in kDa). TERM 4

DAG, IP

DEFINITION 4 Second messengers TERM 5

CD

DEFINITION 5 In immunology, the ------T-Cell Co-Receptor (CD stands for cluster of differentiation) is a protein complex and is composed of four distinct chains.

p56Lck

is essential for initiation of TCR signaling TERM 7

ZAP-

DEFINITION 7 atalyzes phosphorylation of various membrane-associated adaptor molecules TERM 8

DAG

DEFINITION 8 activates the multifunctional protein kinase C, which phosphorylates in various pathways TERM 9

NFAT

DEFINITION 9 Nuclear factor of activated T-cells is a general name applied to a family of transcription factors shown to be important in immune response. TERM 10

NFAT

DEFINITION 10 indirectly activates expression of cytokines which promote thymocyte growth

Fos

is phosphorylated by MAP Kinase and associates with Jun to form AP- TERM 17

AP-

DEFINITION 17 is an essential transcription factor for T cell activation and IL- 2 transcription. TERM 18

Signal 1

DEFINITION 18 is the initial interaction between TCR-CD3 and peptide-MHC. TERM 19

Signal 2

DEFINITION 19 is is provided by thymocyte CD28 and CD152 interaction with B7 proteins on the antigen-presenting cell.