Quick Reference: Blood Components
NL2015-053-TMP
Effective Date: 2015-03-20
Component
ABO/Rh
Compatible
Indication
Size
Storage
Temperature
Transfusion Time
Contraindications
Red Blood Cells
(RBC)
Must be ABO/Rh
Compatible
Rh negative
recipients should
receive Rh negative
red cells
Transfusion of Rh
positive RBC should
be avoided for
Rh-negative women
of child-bearing age
Supplement oxygen-
carrying capacity
(e.g. acute blood
loss, chronic
anemia)
Red blood cell
replacement in
exchange
transfusion
304 ± 61 mLs
per unit
1 to 6 ºC
(for 42 days from
collection date)
If greater than 6ºC,
must be transfused
within four (4) hours
One to two (1-2)
hours (unless
otherwise ordered
by prescriber) to a
maximum of four (4)
hours from time of
removal from
temperature
controlled storage
Clinical situations
where limited oxygen-
carrying capacity is not
due to red cell
deficiency or
dysfunction.
Platelets
Should be ABO
Compatible
Deficient platelet
count due to
production failure
and/or dysfunction
Prophylaxis of
bleeding for invasive
procedures in
thrombocytopenic
patients
Massive
hemorrhage
342 ± 31mLs
per pooled
platelet dose
329 ± 194mLs
per apheresis
bag
20-24 ºC under
continuous agitation (for
five [5] days)
Infuse as rapidly as
possible after initial
15 minutes, up to
one hour (1), if
tolerated
Recipients with rapid
platelet destruction
associated with ITP
(unless life-threatening
bleeding)
Not recommended for
HIT or TTP.
Plasma:
Fresh Frozen (FP)
Apheresis Fresh
Frozen (FFPA)
Cryosupernatant (CSP)
Must be ABO
Compatible
FP/ FFPA
Management of
bleeding in patients
with INR >1.7 who
require replacement
of multiple
coagulation factors
Reversal of INR
FP:
293± 32 mLs
FFPA:
495 ± 59mLs
FP: -18 ºC;
Five (5) days at 1-6 ºC
FFPA: -18ºC;
24 hours at 1-6ºC
Infuse as rapidly as
possible after initial
15 minutes, up to
one hour (1), if
tolerated
Single factor deficiency
treatment if deficiency-
specific recombinant or
plasma-derived
products available
If coagulopathy can be
more appropriately
