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PTCB Test with Questions and Solutions Which of the following medications is a proton pump inhibitor ? A. Nexium B. Norvasc C. Altoprev D. Benicar ANSWERV ¥ The key (A ) is correct because Nexium ( esomeprazole ) is a proton pump inhibitor . Distractor ( B ) is a calcium channel blocker ; distractor ( C ) is an HMG - CoA reductase inhibitor ( statin ) ; and distractor ( D ) is an angiotensin I] receptor blocker . According to federal law , the prescriber's DEA number must be included on a prescription for : A. Buspar B. Zoloft C. Ambien D. Vistaril ANS WERV V The key (C ) is correct because the Code of Federal Regulations requires prescriptions for controlled prescribed , and directions for use ; and the name , address and Drug Enforcement Administration ( DEA ) registration number of the prescriber , and Ambien ( zolpidem ) is federally listed in substances to be dated as of , and signed on , the day when issued and to include the full name and address of the patient . the drug name , strength , dosage form . quantity Schedule IV . Distractors (A) ,(B). and (D ) are not controlled substances Which of the following is a therapeutic substitution for Crestor ? A. Cimetidine B. Simvastatin C. Atovaquone D. Lisinopril ANSWERV V The key ( B ) is correct because Crestor ( rosuvastatin ) and simvastatin are both HMG - CoA reductase inhibitors ( statins ) indicated to lower cholesterol . Distractor ( A ) is a histamine H2 antagonist indicated for heartburn or gastroesophageal reflux disease ; distractor ( C ) is an antiprotozoal indicated for the prophylaxis and treatment of a particular type of pneumonia ; and distractor ( D ) is an angiotensin - converting enzyme ( ACE ) inhibitor indicated for the treatment of heart failure and chronic hypertension . An expired medication should be removed from inventory and : A, Sealed in a plastic bag, then placed in the trash B. Kept in a designated isolated area C. Donated to a non-profit organization D. Used for investigation purposes ANS WERV ¥ The key (B ) is correct because expired products should be removed from dispensing stock and segregated until they may be disposed of appropriatcly Which of the following is an antitubercular agent ? A, Isoniazid B. Cyanocobalamin C. Sumatriptan D. Hydrochlorothiazide ANSWERV V The key ( A ) is correct because isoniazid is an antitubercular agent indicated for tuberculosis prophylaxis and treatment . Distractor (B ) , also known as vitamin B12, is indicated for vitamin B12 deficiency ; distractor ( C ) is indicated for the acute treatment of moderate to severe migraines ; and distractor ( D ) is indicated for the treatment of edema ( swelling ) and the management of chronic hypertension The abbreviation " a.c. " stands for : A. Around the clock C. June 30, 2026 D. July 1, 2026 ANSWERV ¥ The key ( C ) is correct because if an expiration date is stated only in terms of the month and the year , the intended expiration date is the last day of the stated month A 10 Ib batch of 10 % hydrocortisone cream , containing hydrocortisone powder and a common base , must be prepared . How many kg of hydrocortisone powder must be used in preparing the cream ? A. 0.454 B. 4.54 C45.4 D. 454 ANSWERV V Answer The key ( A ) is correct and can be calculated as follows . First , convert 10 Ib to kg using the conversion 2.2 lb 1 kg: (2.2 Ib/ 1 kg) (10 Ib/x kg )x = 4.54 kg Next , since 10 % hydrocortisone cream means that there is 10 g of hydrocortisone in 100 g of cream ( or 10 kg of hydrocortisone in 100 kg of cream ) , sct up a proportion to find how many kg of hydrocortisone there will be in 4.54 kg of cream: (10 kg/ 100 kg) (x kg / 4.54 kg ) x = 0.454 kg hydrocortisone How much 20 mEq / 30 ml . potassium chloride solution , in mL , will deliver a dose of 6.67 mEq ? A.6.67 B.10 C.20 D.30 ANSWERVYV The key (B ) is correct and can be calculated as follows . In order to solve this question , set up a proportion to determine how many mL of potassium chloride solution will provide a 6.67 mLiq dose: (20 mEq / 30 mL )= (6.67 mEg/x mL) x= 10 mL Master Formulation Records are used for which of the following reasons ? A. To evaluate staff performance B. To prevent drug diversion C. To eliminate patient profiles D. To ensure quality control ANSWERV V Answer The key (D) is correct because a Master Formulation Record should be creater before compounding a preparation for the first time and then be followed each time that preparation is made. This helps to ensure that the preparation meets quality standards each time it is made. A patient is picking up a prescription for aripiprazole . A Medication Guide must be given to the patient because the drug A. should be taken with food . B. may increase the risk of suicidal thoughts or actions . C. should only be taken as needed . D. may cause minimal side effects ANSWERVV . Answer The key (B) is correct because antidepressants such as aripiprazole increase the risk of suicidal thinking and behavior and children, adolescence, and young adult adults (18 to 24 years old) with major depressive disorder (MDD) and other psychiatric disorders. The food and drug administration (FDA) requires that medication guides be issued with certain prescribed drugs. and biological products when it is determined that: certain information is necessary to provide serious adverse reactions; patience, decision making should be informed D. 480 ANSWERVV Answer The key (C) is correct and can be calculated as follows First, find how many mL will be needed per day according to the instructions using the conversion | tablespoon (tbsp)=15 mL (2tbsp x 15 mL) x 2 doses per day = 60mL per day ‘Then multiply the dose per day bf the total number of days to find how many mL total are necessary 60mL per day x 7 days= 420 mL Which of the following auxiliary labels is appropriate for Lipitor ? A. Take with food B. Do not take with nitrates C. Do not take with grapefruit juice D. Avoid exposure to sunlight ANSWERV ¥ Answer The key (C) is correct because Lipitor or generic name atorvastatin serum concentration may be increased when taking with grapefruit juice, so current patients should avoid coneurrent intake of large quantities. Lipitor may be administered with or without food and is not known to interact with nitrates or photosensitivity, so distractors (A), (B), and (D) are not applicable A procedure designed to reduce the possibility of a medication error involving high - alert medications in a hospital setting is : A. removing all high - alert medications from inventory . B. placing highly visible signage on all high - alert medications . C. placing high - alert medications in nursing in floor stock . D. expanding access to high - alert medications. ANSWERVV/ Answer The key (B) is correct because the American society of health system pharmacist (ASHP) and the Institute for safe medication practices (ISMP) false recommend using auxiliary labels and alerts to help avoid errors involving high alert medication's. Distractor A is a non-realistic solution, and distractors C and D may actually increase the risk of errors involving high alert medication's. The generic name for Valtrex A. lamivudine . B. zidovudine . C. ritonavir . D. valacyclovir. ANSWERV J Answer The key (D) is correct because valacyclovir is the generic name for valtrex. Distractor A is the generic name for epivir; distractor B is the generic name for retrovir; and distractor is the generic name for norvir Profound sedation , respiratory depression , coma , or death may occur when clonazepam is taken concomitantly with : A. tamoxifen . B. tramadol . C Truvada . D. Tradjenta ANSWERVV . Answer The key (B) is correct because concomitant ise of benzodiazepines like clonazepam and opiates like tramadol may result in profound sedation, respiratory depression, coma, and death. Distractors A, C, and D do not produce this effect when taken concurrently with benzodiazepines According to federal law . if a bottle of Lyrica is transferred from one pharmacy to another , what is the minimum number of years that the transfer records must be maintained ? Al The key (A) is correct because the Code of Federal Regulations prohibits refilling of scheduled 2 controlled substances, and methadone is federally listed in schedule 2 If a caustic material comes in contact with the skin or eyes , the immediate response should be to: A. lic down and cover the affected area . B. call 911 and wait until medical personnel arrive . C. wash the area thoroughly with an antibacterial soap and warm water . D. flush the affected area with large volumes of cold water. ANSWERV ¥ Answer The key (D) is correct because the occupational safety and health administration(OSHA) advises personal who skin has come in direct contact with hazardous drugs to immediately cleanse the affected skin with soap and water and whose eyes have come in direct contact with hazardous drugs to flood the affected cye at an eyewash fountain or with water or isotonic eyewash designed for that purpose for at least 15 minutes When repackaging 2.5 mg methotrexate tablets , a pharmacy technician should keep in mind that this medication : A . need not be protected from light . B. can be crushed . C. is a chemotherapy agent . D. must be stored in the refrigerator ANSWERV V Answer The key (C) is correet because methotrexate is an antincoplastic agent (chemotherapy drug) with indications related to multiple types of cancer as well as psoriasis and rheumatoid arthritis. Methotrexate tablets must be protected from light and stored at room temperature, so distractors A and D are not applicable. Additionally, the tablets should not be crushed during repackaging, so distractor B is also incorrect. Upon receiving a notice of a drug recall , what should a pharmacy technician immediately do with medication labeled with the affected lot number ?? A, Send it to the FDA for testing B. Destroy it C. Quarantine it for return D. Notify the CDC that the pharmacy has it ANS WERV V Answer The key (C) is correct because on receipt of a recall notice, a pharmacy staff member should check our pharmaccutical inventory stores to determine whether any of the recall products are in stock. If a recalled product is in stock, it should be gathered,packaged, and returned according to the directions in the notice or standard operating procedures. Typically recall products are identified using the national drug code number(NCD) and lot number Which of the following organizations sponsors National Prescription Drug Take Back Day events ? A. EPA B.DEA C. OBRA D.OSHA ANSWERV ¥ Answer The key (B) is correct because the drug enforcement administration (DEA) sponsors national prescription take back event so America consumers can properly dispose of unwanted or expired medication's. With regard to inpatient care , the utilization of electronic medication ordering reduces : A. dispensing efficiency . B. drug formulary options . C. adverse drug events . D. number of medications dispensed ANSWERV V . First , set up a proportion to convert either the recommended dose or the total available so that both strengths are in the same unit using the conversion 1000 meg = 0.001 g: (50 meg / x g (1000 meg/0.001g) x = 0.00005 g¢ or (0.02 g/ x meg )=(0.001g/1000 meg) x = 20,000 meg Next , divide the total available by the recommended dose to find how many doses are available : 0.02 g / 0.00005 g 400 doses or 20,000 meg / 50 meg — 400 doses A pharmacy technician must repackage a 4 07 bulk bottle of syrup into six equal individual doses . The volume , in ml , of each dose will be : A. 10 B. 15 Cc. 20 D. 40 ANSWERVV The key ( C ) is correet and can be calculated as follows . In order to solve this problem , it is necessary to convert 4 oz to mL using the conversion | oz — 30 mL (402/x mL)-( 1 02/30 mL)x=120 mL. Next , divide the total mL by the total number of doses to find the volume of each dose: 120 mL total /6 doses = 20 mL per dose Fentanyl transdermal patches typically should be changed every : A. 24 hours B . 36 hours . C. 72 hours . D. 96 hours. ANSWERV ¥ Answer C every 72 hours Which of the following provides guidance for handling hazardous substances ? A. Clinical Pharmacology B. Physicians ' Desk Reference C. Safety Data Sheets D The Red Book ANSWERV V Answer C is the correct answer because chemical manufacturers, distributors, and importers are required by law to provide a safety data sheet for each hazardous chemical to inform users about the hazards associated with the chemical. Safety data sheets include information such as the properties of each chemical; the physical, health, and environmental health hazards; protective measures; and safety precautions for handling, storing, and transporting the eet the chemical. Distractor A is a reference that provides information on how medication's body: distractor B is a reference that contains the compilation of package inserts for prescription drugs; and distractor D is a reference that includes pricing information on prescriptions and over-the-counter pharmaceuticals. Gemfibrozil is indicated to treat elevated levels of : A. hemoglobin B. potassium . C. urokinase . D. triglycerides. ANSWERV V Answer D is the correct answer because gemfibrozil is a fabric acid derivative indicated for the treatment of high cholesterol and prevention of cardiovascular disease A pharmacy technician enters an order for Janumet XR 50/1000 as Janumet 50/1000 . What type of error has taken place ? A. Transcription B. Missed dose conditions . There is an extremely high risk of severe birth defects resulting if pregnancy occurs while taking isotretinoin in any amount , even for a short period of time . Additionally , patients on isotretinoin have been known to become depressed or to develop other serious mental health problems . Some people have had thoughts of hurting themselves or putting an end to their own lives . There have also been reports that people on isotretinoin have exhibited aggression or violence . Which of the following dosage forms of medications is designed to dissolve in the intestine ? A. Enteric - coated tablets B. Troches C. Gelatin capsules D. Film coated tablets ANSWERV V The key (A ) is correct because the actions of enteric - coated tablets are delayed since they must first pass through the stomach and into the intestine before the coating dissolves and the medication absorbs and takes effect . Distractor (B ) is designed to dissolve in the mouth , and distractors (C ) and ( D ) are designed to disintegrate in the stomach . Tinctures that contain high concentrations of alcohol to dissolve the active ingredient may develop which of the following if diluted or mixed with aqueous systems ? A. Emulsion B . Precipitation C. Osmolarity D. Trituration ANSWERV V The key ( B ) is correct because tinctures , such as belladonna and digitalis , that contain high concentrations of alcohol to dissolve the active ingredient (s ) may develop a precipitate if they are diluted or mixed with aqueous systems ( ie . , systems where water is the solvent ) . This is because these tinctures are not water - soluble . Distractor ( A ) refers to a mixture of two liquids that usually do not mix (i.e. , are immiscible ) in which one liquid is broken into small droplets and evenly scattered throughout the other , distractor ( C ) refers to the concentration of a solution expressed as the total number of solute particles per liter ; and distractor ( D ) refers to the process of mixing powders or crushing tablets into a state of fine , evenly - sized particles using a mortar and pestle . 
