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Physiology Exam #3 Contraction of Smooth Muscle | BIOL 2150 - PRINCIPLES OF PHYSIOLOGY, Quizzes of Physiology

Class: BIOL 2150 - PRINCIPLES OF PHYSIOLOGY; Subject: Biology; University: The Richard Stockton College of New Jersey; Term: Fall 2012;

Typology: Quizzes

2011/2012

Uploaded on 11/01/2012

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TERM 1
Step One
DEFINITION 1
extracellular calcium (Ca++) is needed-SR is too small and
cant store enough Ca++-not enough calcium leads
tohypocalcemia
TERM 2
Step Two
DEFINITION 2
calcium binds to calmodulin and activates MLCK
(myosinlight chain kinase)-no troponin
TERM 3
Step Three
DEFINITION 3
Myosin Light Chain Kinase (MLCK) enhances myosin ATPase
activity byphosphorylating light protein chains near the
myosin head.
TERM 4
Step Four
DEFINITION 4
Calcium and calmodulin and MLCK activate myosin heads-
attaches Pi
TERM 5
Step Five
DEFINITION 5
cross bridges form with actin( light protein chains on myosin
head are phosphorylated to allow this binding)
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TERM 1

Step One

DEFINITION 1 extracellular calcium (Ca++) is needed-SR is too small and cant store enough Ca++-not enough calcium leads tohypocalcemia TERM 2

Step Two

DEFINITION 2 calcium binds to calmodulin and activates MLCK (myosinlight chain kinase)-no troponin TERM 3

Step Three

DEFINITION 3 Myosin Light Chain Kinase (MLCK) enhances myosin ATPase activity byphosphorylating light protein chains near the myosin head. TERM 4

Step Four

DEFINITION 4 Calcium and calmodulin and MLCK activate myosin heads- attaches Pi TERM 5

Step Five

DEFINITION 5 cross bridges form with actin( light protein chains on myosin head are phosphorylated to allow this binding)

TERM 6

Step Six

DEFINITION 6 high myosin ATPase activity occurs = causes the binding with actin TERM 7

Step Seven

(Relaxation)

DEFINITION 7 dephosphorylation of myosin light chainphosphatase(MLCP)- stops ATPase TERM 8

Step Eight (Relaxation)

DEFINITION 8 Ca++ and Na+ exchange to get calcium out of cytoplasm TERM 9

Step Nine (Relaxation)

DEFINITION 9 calmodulin uncomplexes TERM 10

Step Ten (relaxation)

DEFINITION 10 MLCK inactivated(myosin light chain kinase)