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PhysioEx Lab Report
Exercise 4 : Endocrine System Physiology
Activity 4 : Measuring Cortisol and Adrenocorticotropic Hormone
Name: Jordan Lark
Date: 20 January 2022
Session ID: session-5b9b11b1-53a6-acfc-b9f2-8e1c190b1ba
Pre-lab Quiz Results
You scored 100% by answering 5 out of 5 questions correctly.
Experiment Results
Predict Questions
No Predict Questions
Stop & Think Questions
Experiment Data
Cortisol
You correctly answered: is a hormone important in the body's response to stress.
ACTH
You correctly answered: is a tropic hormone that stimulates cortisol release.
CRH
You correctly answered: has a tropic effect on the anterior pituitary gland.
Cushing's syndrome refers to
You correctly answered: a hypercortisolism, which could be iatrogenic.
A condition of hypocortisolism
You correctly answered: refers to low levels of cortisol in the blood.
Normally high levels of cortisol would inhibit release of
You correctly answered: both ACTH and CRH.
Which hormone(s) stimulate(s) the pituitary gland to release ACTH?
You correctly answered: CRH.
Patient Cortisol (mcg/dl)
High or low ACTH (pg/ml) High or low
1 2.33 Low 17.23 Low 2 35.72 High 14.24 Low 3 48.33 High 88.18 High 4 2.27 Low 103.44 High 5 50.61 High 17.95 Low
Table 4.1 Cortisol and ACTH Disorders
Cortisol Level ACTH Level Cushing's syndrome (primary hypercortisolism)
High Low
latrogenic Cushing's syndrome High Low
Cushing's disease (secondary hypercortisolism) High High
Addision's disease (primary adrenal insufficiency) Low High
Secondary adrenal insufficiency (hypopituitarism) Low Low
Post-lab Quiz Results
You scored 100% by answering 6 out of 6 questions correctly.
Under normal conditions, if the amount of secreted CRH increases, then
You correctly answered: the amount of secreted ACTH will increase.
Under normal conditions, if the amount of secreted ACTH increases, then
You correctly answered: the amount of secreted CRH will likely decrease.
Under normal conditions, if the amount of secreted cortisol increases, then
You correctly answered: the amount of secreted ACTH will likely decrease.
If a hypersecreting pituitary tumor develops, then an expected outcome is
You correctly answered: a diagnosis of Cushing's disease.
If a hypersecreting adrenal cortex tumor develops, then an expected outcome is
You correctly answered: abnormally low levels of CRH due to negative feedback.
