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PhysioEx Lab Report
Exercise 4 : Endocrine System Physiology Activity 3 : Hormone Replacement Therapy Name: Jordan Lark Date: 20 January 2022 Session ID: session-240dbb7d-b68e-2d86-ee88-a3c970d7dfd
Pre-lab Quiz Results
You scored 100% by answering 4 out of 4 questions correctly.
Experiment Results
Predict Questions Follicle-stimulating hormone (FSH) You correctly answered: stimulates ovarian follicle development.
Estrogen You correctly answered: is produced by developing ovarian follicles.
Calcitonin You correctly answered: works against the development of osteoporosis.
Which of the following statements is true? You correctly answered: The ovaries stop secreting estrogen after menopause.
Predict Question 1: What effect will the saline injections have on the control rat's vertebral bone density? Your answer: The saline injections will not change the rat's vertebral bone density (indicated by an unchanging T score).
Predict Question 2: What effect will the estrogen injections have on the estrogen-treated rat's vertebral bone density? Your answer: The estrogen injections will increase the rat's vertebral bone density (indicated by a less-negative T score).
Predict Question 3: What effect will the calcitonin injections have on the calcitonin-treated rat's vertebral bone density?
Stop & Think Questions Experiment Data Rat Elapsed Days Saline injections Estrogen injections Calcitonin injections T score Control 7 7 0 0 -2. Estrogen 7 0 7 0 -1. Calcitonin 7 0 0 7 -2.
Post-lab Quiz Results
You scored 100% by answering 4 out of 4 questions correctly.
Review Sheet Results
Your answer: The calcitonin injections will increase the rat's vertebral bone density (indicated by a less-negative T score). Saline injections were used in this experiment to measure the effect of You correctly answered: a placebo on bone density.
In the ovariectomized rats used in this experiment You correctly answered: osteoporosis was evident prior to the injections of estrogen.
Injection of calcitonin into an ovariectomized rat will You correctly answered: inhibit osteoclast activity and stimulate calcium uptake and deposition in long bones.
As the rat's bone density increases You correctly answered: the X-ray scanning assay reports a less-negative T-score.
Why were ovariectomized rats used in this experiment? How does the fact that the rats are ovariectomized explain their baseline T scores? Your answer: Ovariectomized rats were used because these rats are no longer producing estrogen and will exhibit bone loss due to osteoporosis. There T scores are going to be at or below -2. because of the amount of bone loss they have suffered.
What effect did the administration of saline injections have on the control rat? How well did the results compare with your prediction?
