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Pharmacotherapeutics For Advanced Practice Nurse Prescribers: Chapter 6. An Introduction To Pharmacogenomics Exam Questions With Verified Answers
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Genetic polymorphisms account for differences in metabolism, including:
ANS: 4
Up to 21% of Asians are ultra-rapid 2D6 metabolizers, leading to:
ANS: 2
Rifampin is a nonspecific CYP450 inducer that may:
ANS: 3
Inhibition of P-glycoprotein by a drug such as quinidine may lead to:
ANS: 4
Warfarin resistance may be seen in patients with a VKORC1 mutation, leading to:
ANS: 3
A genetic variation in how the metabolite of the cancer drug irinotecan SN-38 is inactivated by the body may lead to:
ANS: 2
Patients who have a poor metabolism phenotype will have:
ANS: 1
Ultra-rapid metabolizers of drugs may have:
ANS: 2
A provider may consider testing for CYP2D6 variants prior to starting tamoxifen for breast cancer to:
ANS: 3