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Pharmacology Questions and Answers: Chapter 3 - Stahl's Essential Psychopharmacology, Exams of Nursing

New Jersey City University (NJCU)Nursing

A series of questions and answers related to chapter 3 of stahl's essential psychopharmacology, focusing on key concepts like receptor interactions, agonist/antagonist mechanisms, and voltage-sensitive channels. It covers topics such as ligand-gated ion channels, allosteric modulators, and the structure and function of voltage-sensitive sodium and calcium channels. Valuable for students studying pharmacology and neuroscience, offering a concise review of important concepts and their applications.

Typology: Exams

2024/2025

Available from 01/02/2025

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nurs 670 pharmacology stahl ch 3
questions with answers
antagonist at receptor - ....🔰VERIFIED ANSWERS.... ✔✔neutral or silent
ligand gated receptors are on the agonist spectrum? - ....🔰VERIFIED
ANSWERS.... ✔✔yes
agonist spectrum - ....🔰VERIFIED ANSWERS.... ✔✔full agonist, partial
agonist, antagonist. Also with an allosteric modulator, can open to an even
greater extent than full agonist. Inverse agonist (closes channel-blocks the
resting state)
antagonist - ....🔰VERIFIED ANSWERS.... ✔✔stabilizes receptor in its resting
state, blocking agonist
partial agonist for ligand gated channel - ....🔰VERIFIED ANSWERS....
✔✔opens greater than resting state, but less than full agonist
partial agonist aka - ....🔰VERIFIED ANSWERS.... ✔✔stabilizers (they can
find that goldilocks zone between too much and too little
inverse agonists produce less of a response than... - ....🔰VERIFIED
ANSWERS.... ✔✔antagonists (which keep the channel in resting or
constitutive)
opposite of agonist - ....🔰VERIFIED ANSWERS.... ✔✔antagonist, not inverse
agonist
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Download Pharmacology Questions and Answers: Chapter 3 - Stahl's Essential Psychopharmacology and more Exams Nursing in PDF only on Docsity!

nurs 670 pharmacology stahl ch 3

questions with answers

antagonist at receptor - .... 🔰 VERIFIED ANSWERS.... ✔✔ neutral or silent ligand gated receptors are on the agonist spectrum? - .... 🔰 VERIFIED ANSWERS.... ✔✔ yes agonist spectrum - .... 🔰 VERIFIED ANSWERS.... ✔✔ full agonist, partial agonist, antagonist. Also with an allosteric modulator, can open to an even greater extent than full agonist. Inverse agonist (closes channel-blocks the resting state) antagonist - .... 🔰 VERIFIED ANSWERS.... ✔✔ stabilizes receptor in its resting state, blocking agonist partial agonist for ligand gated channel - .... 🔰 VERIFIED ANSWERS.... ✔✔ opens greater than resting state, but less than full agonist partial agonist aka - .... 🔰 VERIFIED ANSWERS.... ✔✔ stabilizers (they can find that goldilocks zone between too much and too little inverse agonists produce less of a response than... - .... 🔰 VERIFIED ANSWERS.... ✔✔ antagonists (which keep the channel in resting or constitutive) opposite of agonist - .... 🔰 VERIFIED ANSWERS.... ✔✔ antagonist, not inverse agonist

states that a ligand gated ion channel can be in - .... 🔰 VERIFIED ANSWERS.... ✔✔ open, resting, closed, desensitization, desensitized state - .... 🔰 VERIFIED ANSWERS.... ✔✔ too much ligand- the receptor can close off, not reacting to ligand. When the agonist goes away it can take hours to return to sensitivity (and then you smoke another cigarette) allosteric means - .... 🔰 VERIFIED ANSWERS.... ✔✔ other site allosteric modulators NTs? - .... 🔰 VERIFIED ANSWERS.... ✔✔ no, they have no effect in the absence of NT PAM - .... 🔰 VERIFIED ANSWERS.... ✔✔ positive allosteric modulator, enhances agonist nam - .... 🔰 VERIFIED ANSWERS.... ✔✔ negative am. blocks agonist. example of PAM - .... 🔰 VERIFIED ANSWERS.... ✔✔ benzos. Enhance the action of GABA. nam example - .... 🔰 VERIFIED ANSWERS.... ✔✔ benzo inverse agonist (just experimental right now). Also PCP and ketamine for NMDA. ionic components of an action potential - .... 🔰 VERIFIED ANSWERS.... ✔✔ 1. sodium rushes into the negatively charged and sodium deficient cell

  1. Calcium starts to rush in
  2. at the end of the action potential, potassium rushes in as sodium is pumped out

VSSC are related to - .... 🔰 VERIFIED ANSWERS.... ✔✔ anticonvulsants VSCC similarities to VSSC - .... 🔰 VERIFIED ANSWERS.... ✔✔ 6 transmembrane, 4 subunit, segment 4 voltmeter, filter between TM 5 and 6. Differences between VSCC and VSSC - .... 🔰 VERIFIED ANSWERS.... ✔✔ no bathtub plug at TM 3 and 4. TM 2 and 3 there is a "snare". VSCC TM 2 and 3 snare function - .... 🔰 VERIFIED ANSWERS.... ✔✔ hooks up with vesicles for NT release VSCC calcium channel proteins - .... 🔰 VERIFIED ANSWERS.... ✔✔ several flank the alpha 1 pore-forming unit VSCC protein subunits - .... 🔰 VERIFIED ANSWERS.... ✔✔ beta, gamma, alpha 2 delta alpha 2 delta is associated with - .... 🔰 VERIFIED ANSWERS.... ✔✔ pregabalin, gabapentin, changing the opening and closing of the channel. subtypes of VSCC most of interest to psychopharm - .... 🔰 VERIFIED ANSWERS.... ✔✔ N, P/Q pg 72 Which channel do CCBs act on? - .... 🔰 VERIFIED ANSWERS.... ✔✔ L channel proteins that link VSCC to the synaptic vesicle - .... 🔰 VERIFIED ANSWERS.... ✔✔ synaptotagmin, synaptobrevin, snap 25