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Essential Psychopharmacology 7th Edition
Which of the following is a common side effect of selective serotonin reuptake inhibitors (SSRIs)? A. Weight loss B. Dry mouth C. Sexual dysfunction D. Hypotension Answer: C. Sexual dysfunction What is the primary mechanism of action of atypical antipsychotics? A. Dopamine D2 receptor antagonism B. Serotonin 5-HT2A receptor antagonism C. Norepinephrine reuptake inhibition D. Histamine H1 receptor antagonism Answer: B. Serotonin 5-HT2A receptor antagonism Which medication is typically used as a first-line treatment for bipolar disorder during a manic episode? A. Lithium B. Valproate C. Lamotrigine D. Olanzapine Answer: B. Valproate Which of the following is a potential adverse effect of tricyclic antidepressants (TCAs)? A. Akathisia
B. Weight gain C. Anticholinergic effects D. Hyperprolactinemia Answer: C. Anticholinergic effects Which class of medications is considered most effective in the treatment of generalized anxiety disorder (GAD)? A. Benzodiazepines B. SSRIs C. Antipsychotics D. Mood stabilizers Answer: B. SSRIs Which of the following is a common side effect of atypical antipsychotics that is often referred to as metabolic syndrome? A. Weight gain B. Tremor C. Tardive dyskinesia D. Agranulocytosis Answer: A. Weight gain What is the mechanism of action of monoamine oxidase inhibitors (MAOIs)? A. Inhibition of serotonin reuptake B. Inhibition of dopamine reuptake C. Inhibition of monoamine oxidase enzyme D. Antagonism of serotonin receptors Answer: C. Inhibition of monoamine oxidase enzyme
C. Risperidone D. Valproate Answer: B. Clomipramine Which drug is used primarily for the treatment of attention deficit hyperactivity disorder (ADHD) and acts as a central nervous system stimulant? A. Atomoxetine B. Methylphenidate C. Bupropion D. Desvenlafaxine Answer: B. Methylphenidate Which of the following is a potential severe side effect of the antipsychotic drug clozapine? A. Hyperglycemia B. Agranulocytosis C. Hypotension D. Sedation Answer: B. Agranulocytosis Which class of antidepressants is associated with the risk of hypertensive crisis when consumed with tyramine-rich foods? A. SSRIs B. SNRIs C. TCAs D. MAOIs Answer: D. MAOIs
Which antipsychotic medication has a partial agonist effect on dopamine D receptors? A. Olanzapine B. Aripiprazole C. Quetiapine D. Risperidone Answer: B. Aripiprazole Which antipsychotic medication is known for having a lower risk of extrapyramidal symptoms (EPS)? A. Haloperidol B. Olanzapine C. Chlorpromazine D. Perphenazine Answer: B. Olanzapine Which class of medications is typically used as first-line treatment for panic disorder? A. Benzodiazepines B. Antipsychotics C. SSRIs D. MAOIs Answer: C. SSRIs Which of the following drugs is commonly used as an adjunctive treatment for depression, particularly in patients who have not responded to other antidepressants? A. Lithium B. Bupropion
Which medication is often used to manage the symptoms of generalized anxiety disorder (GAD) and is known for its minimal sedative effects? A. Buspirone B. Diazepam C. Lorazepam D. Clonazepam Answer: A. Buspirone Which drug is known for its effectiveness in treating both depressive and anxiety symptoms, but may cause insomnia and agitation in some patients? A. Trazodone B. Mirtazapine C. Sertraline D. Nefazodone Answer: C. Sertraline Which medication is used to manage bipolar disorder and requires regular monitoring of blood levels due to its narrow therapeutic window? A. Valproate B. Lithium C. Lamotrigine D. Carbamazepine Answer: B. Lithium Which of the following drugs is primarily used for its mood-stabilizing properties in bipolar disorder and has a mechanism of action that is not fully understood? A. Lithium B. Lamotrigine
C. Valproate D. Olanzapine Answer: C. Valproate Which medication is often prescribed as an adjunct treatment for major depressive disorder and has a mechanism involving the inhibition of norepinephrine and dopamine reuptake? A. Bupropion B. Sertraline C. Fluoxetine D. Escitalopram Answer: A. Bupropion Which of the following is a key advantage of using buspirone for the treatment of generalized anxiety disorder (GAD)? A. Rapid onset of action B. Minimal sedative effects C. Potent muscle relaxant properties D. High efficacy in treating panic disorder Answer: B. Minimal sedative effects Which medication is used primarily for its mood-stabilizing effects in bipolar disorder and has the potential to cause a rash that could be life-threatening? A. Lithium B. Lamotrigine C. Valproate D. Olanzapine Answer: B. Lamotrigine
C. Carbamazepine D. Lamotrigine Answer: B. Valproate Which of the following antidepressants is known for its potential to cause significant weight gain and sedation? A. Fluoxetine B. Sertraline C. Mirtazapine D. Bupropion Answer: C. Mirtazapine Which antipsychotic is associated with a lower risk of metabolic side effects and is often preferred for patients with metabolic concerns? A. Olanzapine B. Risperidone C. Aripiprazole D. Quetiapine Answer: C. Aripiprazole Which class of medications is often used as an adjunctive treatment for insomnia in patients with depression or anxiety disorders? A. SSRIs B. Benzodiazepines C. Antipsychotics D. Non-benzodiazepine hypnotics Answer: D. Non-benzodiazepine hypnotics
Which medication is known for its efficacy in reducing alcohol cravings and is used as part of alcohol dependence treatment? A. Disulfiram B. Naltrexone C. Acamprosate D. Topiramate Answer: B. Naltrexone Which of the following is a potential side effect of selective serotonin and norepinephrine reuptake inhibitors (SNRIs)? A. Bradycardia B. Hypertension C. Weight loss D. Hyperglycemia Answer: B. Hypertension Which medication is often used as a first-line treatment for acute agitation in psychotic disorders and has a rapid onset of action? A. Haloperidol B. Clozapine C. Ziprasidone D. Olanzapine Answer: A. Haloperidol Which of the following is a major concern when prescribing tricyclic antidepressants (TCAs) to elderly patients? A. Orthostatic hypotension B. Insomnia
Which medication is commonly used to manage opioid withdrawal symptoms and works by acting as a partial agonist at opioid receptors? A. Methadone B. Buprenorphine C. Naloxone D. Naltrexone Answer: B. Buprenorphine Which of the following medications is used to treat insomnia and acts on the melatonin receptors? A. Zolpidem B. Eszopiclone C. Ramelteon D. Trazodone Answer: C. Ramelteon Which antidepressant is known for its activating effects and is often preferred for patients with low energy and fatigue? A. Paroxetine B. Mirtazapine C. Fluoxetine D. Bupropion Answer: D. Bupropion Which of the following is a common side effect of lithium therapy? A. Hepatotoxicity B. Nephrotoxicity C. Thyroid dysfunction
D. Agranulocytosis Answer: C. Thyroid dysfunction Which antipsychotic medication is associated with a high risk of weight gain and metabolic syndrome? A. Ziprasidone B. Lurasidone C. Olanzapine D. Aripiprazole Answer: C. Olanzapine Which class of medications is commonly used as mood stabilizers in bipolar disorder and also has antiepileptic properties? A. SSRIs B. SNRIs C. Anticonvulsants D. Antipsychotics Answer: C. Anticonvulsants Which of the following medications is primarily used for the treatment of narcolepsy and is known to promote wakefulness? A. Modafinil B. Methylphenidate C. Amphetamine D. Atomoxetine Answer: A. Modafinil Which medication is used to treat social anxiety disorder and works by inhibiting the reuptake of serotonin and norepinephrine?
Answer: B. Lower risk of tardive dyskinesia Which medication is commonly prescribed for post-traumatic stress disorder (PTSD) and works by blocking adrenergic receptors? A. Sertraline B. Paroxetine C. Prazosin D. Venlafaxine Answer: C. Prazosin Which of the following medications is known for its use in the treatment of fibromyalgia and chronic pain conditions? A. Duloxetine B. Sertraline C. Fluoxetine D. Citalopram Answer: A. Duloxetine Which medication is used for smoking cessation and works by acting as a partial agonist at the nicotinic acetylcholine receptors? A. Bupropion B. Varenicline C. Nicotine replacement therapy D. Clonidine Answer: B. Varenicline Which of the following medications is commonly used to treat opioid dependence and requires certification for prescribing?
A. Methadone B. Buprenorphine C. Naloxone D. Naltrexone Answer: B. Buprenorphine Which class of medications is typically avoided in patients with a history of bipolar disorder due to the risk of triggering manic episodes? A. SSRIs B. Antipsychotics C. Benzodiazepines D. Mood stabilizers Answer: A. SSRIs Which of the following medications is known for its off-label use in treating hot flashes in menopausal women? A. Venlafaxine B. Paroxetine C. Sertraline D. Fluoxetine Answer: B. Paroxetine Which medication is commonly used to treat restless legs syndrome and works by mimicking dopamine? A. Gabapentin B. Ropinirole C. Pregabalin D. Carbamazepine Answer: B. Ropinirole
B. Buprenorphine C. Naloxone D. Naltrexone Answer: C. Naloxone Which of the following medications is commonly prescribed for the treatment of insomnia and is classified as a non-benzodiazepine hypnotic? A. Diazepam B. Zolpidem C. Lorazepam D. Clonazepam Answer: B. Zolpidem Which medication is often used for the treatment of post-herpetic neuralgia and has a mechanism involving calcium channel modulation? A. Gabapentin B. Duloxetine C. Amitriptyline D. Pregabalin Answer: A. Gabapentin Which of the following medications is known for its mood-stabilizing properties and is also used in the treatment of epilepsy? A. Valproate B. Olanzapine C. Risperidone D. Quetiapine Answer: A. Valproate
Which medication is commonly used to treat neuropathic pain and works by inhibiting norepinephrine and serotonin reuptake? A. Amitriptyline B. Nortriptyline C. Venlafaxine D. Duloxetine Answer: D. Duloxetine Which of the following medications is often prescribed for generalized anxiety disorder and is classified as a serotonin-norepinephrine reuptake inhibitor (SNRI)? A. Paroxetine B. Venlafaxine C. Sertraline D. Fluoxetine Answer: B. Venlafaxine Which medication is used to manage agitation in patients with dementia and has a relatively low risk of extrapyramidal symptoms (EPS)? A. Haloperidol B. Risperidone C. Quetiapine D. Aripiprazole Answer: C. Quetiapine Which of the following medications is used to treat alcohol dependence and works by inhibiting aldehyde dehydrogenase? A. Disulfiram B. Naltrexone
