Download PHARMACOLOGY NURS 251 MODULE 9 EXAM PORTAGE LEARNING QUESTIONS AND ANSWERS and more Exams Pharmacology in PDF only on Docsity!
1. Select the characteristic below that is consistent with a specialty medica-
tion. -Not covered by insurance -Treat a complex disease state -Any injectable -Needs to be refrigerated Ans> Treat a complex disease state
2. Select the characteristic below that is NOT consistent with a specialty
medication.
Ans> Any injectable
3. T/F; Patients must go through a specialty pharmacy to obtain a medication
that is considered a specialty medication; retail pharmacies do not stock them.
PHARMACOLOGY NURS 251 MODULE 9
EXAM PORTAGE LEARNING
True
4. T/F; Specialty pharmacies represent one option for patients to obtain spe-
cialty medications; however, they are still able to access them through stan- dard retail pharmacies if they prefer False
5. List three characteristics of specialty medications.
High cost, treats rare diseases, complex treatment regimen
6. List three classes of medications that are considered specialty medications. (
point each) Antivirals for Hep C, Biologics, Interleukins
7. List three disease states that are commonly treated with a specialty med-
ication RA, Oncology, Hep C
8. Match the disease state with the appropriate medication used to treat it. (
point each)
- Cancer -Multiple Sclerosis -Rheumatoid Arthritis -Crohn's Disease
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12. Select the true statement regarding immunomodulating drugs.
-Many are found naturally in the environment -They have been around since the 1950s -They work strictly by enhancing the patient's natural immune response -They in large part have contributed to the growth of specialty pharmacy They in large part have contributed to the growth of specialty pharmacy
13. Select the false statement regarding immunomodulating drugs.
They work strictly by enhancing the patient's natural immune response
14. T/F;. Cell-mediated immunity involves the production of antibodies.
Ans> False
15. T/F; Humoral immunity involves the production of antibodies.
Ans> True
16. What type of immune cells recognize and rupture target cells that have
foreign antigens on their surface? Cytotoxic T cells
17. What is the type of immune response mediated by T-cells?
Cell-mediated immunity
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18. Name three specific types of immunomodulating drugs.
Ans> Interferons, inter- leukins, monoclonal antibodies
19. Provide a specific example of a drug that is anti-TNF monoclonal antibody.-
Ans> Humira
20. Match the specific immunomodulating drug with its trade name. (1 point
each) -Interferon beta-1a
- Adalimumab
- Bevacizumab
- Natalizumab
- Aldeslukin
- Anakinra
Binds to T cell stum Inh binding of 11-1 Inhi T cell activation Binds to TNF prev frm
22. Select the true statement regarding interferon beta-1a.
-It is marketed under the brand names -Avonex and Remicade Avonex is a once weekly subcutaneous injection -It is indicated to treat rheumatoid arthritis -Common adverse events include flu like symptoms Ans> Common adverse events include flu like symptoms
23. Select the immunomodulating drug that is not indicated for the treatment
of RA.
- Adalimumab
- Anakinra Bevacizumab
24. Select the immunomodulating drug that is indicated for the treatment of
RA.
Adalimumab
25. Which immunomodulating drug is associated with the severe toxicity that
leads to leaky capillaries? Proleukin
26. What is the term for cytokines that are produced by the lymphocytes?
Ans> - Lymphokines
27. T/F; In order to take natalizumab, the patient must be enrolled in a
patient safety program due to the risk of a rare viral infection in the brain. True
28. T/F; In order to take natalizumab, the patient must be enrolled in a
patient safety program due to the risk of heart failure exacerbation. False
29. What class of immunomodulating drugs used to include the mainstay of
treatment for hepatitis C? Interferons
30. One of the drugs used in the treatment of hepatitis C is actually an anti-
retroviral. What class of antiretroviral is it in?
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Ans> True
38. What is the term used when a patient with HIV begins acquiring oppor-
tunistic infections? Ans> AIDS
39. Name the two specific immune cell types that the HIV virus attacks.
Ans> - Macrophages, helper T cells
40. Select the true statement regarding HIV and its treatment.
-Initial treatment typically consists of one drug -Treatment is aimed at clearing the virus from the patient's body -Compliance is critical to the success of these drugs -All HIV medications essentially work by the same mechanism Ans> Compliance is critical to the success of these drugs
41. Select the false statement regarding HIV and its treatment.
Ans> All HIV medications essentially work by the same mechanism
42. Match the class of antiretroviral with its mechanism of action.
- NRTI
- NNRTI
-Protease Inhibitor -Integrase Inhibitor -Fusion Inhibitor Ans> -Incorporate themselves into the DNA inhibiting reverse tran- scriptase -Binds to reverse transcriptase and prevents it from working -Prevent the final assembly of the new virus -Prevent the virus from being able to enter the nucleus -Prevent the virus from binding completely to the host cell
46. T/F; Compliance to HIV medications has no effect on the development of
drug resistance. Ans> False
47. Which interleukin covered in this module exerts its effect by enhancing the
immune system? Ans> Aldesleukin (Proleukin)
48. T/F; Bevacizumab is derived from murine myeloma cells?
Ans> False
49. Match the immunomodulating Drug with the correct route of administra-
tion. (1 point each; each answer can be used more than once or not at all)
- Natalizumab
- Infliximab
- Anakinra
- Etanercept -Abatacept Ans> -IV infusion -IV infusion -Subcutaneous injection -Subcutaneous injection -IV infusion
50. Match the immunomodulating Drug with the correct indication.
-Inferon beta 1-a
- Aldekeukin
- Abatacept -Multiple Sclerosis -Crohn's Disease -Colorectal Cancer
- Melanoma
- RA
51. Which of the following immunomodulating drugs is available in an intra-
muscular injection?
- Infliximab
- Anakinra -Interferon beta-1a
- Abatacept Interferon beta-1a
52. Which of the following immunomodulating drugs is available in a subcu-
taneous dose?
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