Pharmacology NURS 251 Module 9 Exam (2025 / 2026) portage learning/Geneva College, Exams of Pharmacology

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PHARMACOLOGY NURS 251 MODULE 9 EXAM

PORTAGE LEARNING

1. Select the characteristic below that is consistent with a specialty medica- tion.

-Not covered by insurance -Treat a complex disease state -Any injectable -Needs to be refrigerated Ans> Treat a complex disease state

2. Select the characteristic below that is NOT consistent with a specialty medication.

-- Ans> Any injectable

3. T/F; Patients must go through a specialty pharmacy to obtain a medication that is considered a specialty medication; retail pharmacies do not stock them.

Ans> True

4. T/F; Specialty pharmacies represent one option for patients to obtain spe- cialty medications; however, they are still able to access them through stan- dard retail pharmacies if they prefer

Ans> False

5. List three characteristics of specialty medications. Ans> High cost, treats rare diseases, complex treatment regimen
6. List three classes of medications that are considered specialty medications. (1 point each) Ans> Antivirals for Hep C, Biologics, Interleukins
7. List three disease states that are commonly treated with a specialty med- ication Ans> RA, Oncology, Hep C
8. Match the disease state with the appropriate medication used to treat it. ( point each)

-Cancer -Multiple Sclerosis -Rheumatoid Arthritis -Crohn's Disease

12. Select the true statement regarding immunomodulating drugs.

-Many are found naturally in the environment -They have been around since the 1950s -They work strictly by enhancing the patient's natural immune response -They in large part have contributed to the growth of specialty pharmacy Ans> They in large part have contributed to the growth of specialty pharmacy

13. Select the false statement regarding immunomodulating drugs.

-- Ans> They work strictly by enhancing the patient's natural immune response

14. T/F;. Cell-mediated immunity involves the production of antibodies. Ans> False
15. T/F; Humoral immunity involves the production of antibodies. Ans> True
16. What type of immune cells recognize and rupture target cells that have foreign antigens on their surface? Ans> Cytotoxic T cells
17. What is the type of immune response mediated by T-cells? Ans> Cell-mediated immunity

18. Name three specific types of immunomodulating drugs. Ans> Interferons, inter- leukins, monoclonal antibodies
19. Provide a specific example of a drug that is anti-TNF monoclonal antibody.-

Ans> Humira

20. Match the specific immunomodulating drug with its trade name. (1 point each)

-Interferon beta-1a -Adalimumab -Bevacizumab -Natalizumab -Aldeslukin -Anakinra

Binds to T cell stum Inh binding of 11- Inhi T cell activation Binds to TNF prev frm

22. Select the true statement regarding interferon beta-1a.

-It is marketed under the brand names -Avonex and Remicade Avonex is a once weekly subcutaneous injection -It is indicated to treat rheumatoid arthritis -Common adverse events include flu like symptoms Ans> Common adverse events include flu like symptoms

23. Select the immunomodulating drug that is not indicated for the treatment of RA.

-Bevacizumab -Etanercept

-Adalimumab -Anakinra Ans> Bevacizumab

24. Select the immunomodulating drug that is indicated for the treatment of RA.

-- Ans> Adalimumab

25. Which immunomodulating drug is associated with the severe toxicity that leads to leaky capillaries? Ans> Proleukin
26. What is the term for cytokines that are produced by the lymphocytes? Ans> - Lymphokines
27. T/F; In order to take natalizumab, the patient must be enrolled in a patient safety program due to the risk of a rare viral infection in the brain. Ans> True
28. T/F; In order to take natalizumab, the patient must be enrolled in a patient safety program due to the risk of heart failure exacerbation. Ans> False
29. What class of immunomodulating drugs used to include the mainstay of treatment for hepatitis C? Ans> Interferons
30. One of the drugs used in the treatment of hepatitis C is actually an anti- retroviral. What class of antiretroviral is it in?

Ans> True

38. What is the term used when a patient with HIV begins acquiring oppor- tunistic infections? Ans> AIDS

39. Name the two specific immune cell types that the HIV virus attacks. Ans> - Macrophages, helper T cells
40. Select the true statement regarding HIV and its treatment.

-Initial treatment typically consists of one drug -Treatment is aimed at clearing the virus from the patient's body -Compliance is critical to the success of these drugs -All HIV medications essentially work by the same mechanism Ans> Compliance is critical to the success of these drugs

41. Select the false statement regarding HIV and its treatment.

-- Ans> All HIV medications essentially work by the same mechanism

42. Match the class of antiretroviral with its mechanism of action.

-NRTI -NNRTI -Protease Inhibitor -Integrase Inhibitor -Fusion Inhibitor Ans> -Incorporate themselves into the DNA inhibiting reverse tran- scriptase -Binds to reverse transcriptase and prevents it from working -Prevent the final assembly of the new virus -Prevent the virus from being able to enter the nucleus -Prevent the virus from binding completely to the host cell

46. T/F; Compliance to HIV medications has no effect on the development of drug resistance. Ans> False
47. Which interleukin covered in this module exerts its effect by enhancing the immune system? Ans> Aldesleukin (Proleukin)
48. T/F; Bevacizumab is derived from murine myeloma cells? Ans> False
49. Match the immunomodulating Drug with the correct route of administra- tion. (1 point each; each answer can be used more than once or not at all)

-Natalizumab -Infliximab -Anakinra -Etanercept -Abatacept Ans> -IV infusion -IV infusion -Subcutaneous injection -Subcutaneous injection -IV infusion

50. Match the immunomodulating Drug with the correct indication.

-Inferon beta 1-a -Adalumumab -Bevacizumab

-Aldekeukin -Abatacept Ans> -Multiple Sclerosis -Crohn's Disease -Colorectal Cancer -Melanoma -RA

51. Which of the following immunomodulating drugs is available in an intra- muscular injection?

-Infliximab -Anakinra -Interferon beta-1a -Abatacept Ans> Interferon beta-1a

52. Which of the following immunomodulating drugs is available in a subcu- taneous dose?

-- Ans> Anakinra