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Pharmaceutical Calculations Questions And
Answers 2024 Latest Updated Graded A+.
How many milliliter of U-100 insulin should be used to obtain 50units of insulin? a. 5ml b. 50mL c. 0.5mL d.500mL - Solution c. 0.5mL How many drops would be prescribed in each dose of a liquid medicine if 20mL contained 60 doses? The dropper calibrates 35gtts per mL. a. 12gtts b.15gtts c. 8gtts d. 23gtts - Solution a. 12gtts How many milligrams of a drug will be needed to prepare 74 dosage forms if each is to contain 1/10 grain? a. 58mg b. 480mg c. 4800mg d. 4.8mg - Solution b. 480mg If a pint of a certain liquid weights 9200 grains, what is the specific gravity of the liquid? a. 1. b. 1. c. 1. d. 1.26 - Solution d. 1. How many grams of dextrose are required to prepare 4500 L of a 5% solution? a. 80,000 g b. 225,000 g c. 4 f d. 8 f3 - Solution b. 225,000 g
How many grams of drug substance should be dissolved in 250 mL of water to make a 5%(w/w) solution? a. 9.6g b.13.16g c.60 g d. 10g - Solution b.13.16g Convert 5% to mg/mL a. 50mg/mL b.500mg/mL c.5000mg/mL d. 5mg/mL - Solution a. 50mg/mL In what proportion should alcohols of 90% and 50% strengths should be mixed to make 70% alcohol? a. 3parts/5parts b.1part/1part c.5parts/4parts d.4parts/5parts - Solution b.1part/1part How many milliliters of two liquids with specific gravities of 0.950 and 0. should be used to prepare 1500mL of a liquid having a specific gravity of 0.925? a.1000mL (sp.gr 0.950) 500mL (sp gr 0.875) b.2250mL (sp.gr 0.950) 1125mL (sp gr 0.875) c.500mL (sp.gr 0.950) 1000mL(sp gr 0.875) d. 1125mL (sp.gr 0.950) 2250mL(sp gr 0.875) - Solution a.1000mL (sp.gr 0.950) 500mL (sp gr 0.875) Zinc chloride is a three-ion electrolyte,dissociating 80% in a certain concentration. Calculate its dissociation factor(I) a. 2. b. 1. c. 2. d. 3 - Solution a. 2. If 10mg of a drug are added to a 500mL large-volume parenteral fluid, what should be the rate of flow, in mL/hr, to deliver 1mg of drug per hour? a. 50mL/hr
d.50 tab - Solution a. 50,000 tab Digitoxin is available for parenteral pediatric use in a concentration of 0.1mg/mL. how many milliliters would provide dose of 40 mcg? a. 0.04mL b. 40mL c. 40mL d. 0.4mL - Solution d. 0.4mL Nitrostat sublingual tablets are available as 1/200gr tablets. What is the approximate equivalent in milligrams? a. 0. b. 0. c. 0. d. 0.65 - Solution a. 0. Four thousand nanograms equals 4: a. centigrams b. grams c. milligrams d. micrograms - Solution d. micrograms The prophylactic dose of riboflavin is 2mg. how many mcg of riboflavin are in a multiple vitamin capsule containing 1/5 the prophylactic dose? a.500mcg b.400mcg c.5000mcg d.200mcg - Solution b.400mcg If a physician prescribed 4g of aspirin to be taken by a patient daily, about how many 5-grain tablets should the patient take each day? a. 10 tab b. 12 tab c.15 tab d.8 tab - Solution b. 12 tab A commercial package contains thirty-six 200mg tablets of ibuprofen. How many kilograms of ibuprofen were used in the manufacture of 1000 package of the product? a. 7.2 kg
b. 5kg c. 7.8kg d. 6.9 kg - Solution a. 7.2 kg How many grams of ethyl estradiol are needed to prepare 2,500 tablets, each containing 50mcg of the medicinal substance? a. 1.25g b.12.5g c. 0.125g d.125g - Solution c. 0.125g Pico denotes _______ of the basic unit a. 10^- b. 10^- c.10^- d. 10^-10 - Solution a. 10^- 1 milliliter is 1000x greater than: a. microliter b.picoliter c.nanoliter d.liter - Solution a. microliter Sudafed cough syrup contains 0.0g of dextromethorphan hydrobromide in each fluidounce. How many milligrams of this agent would be present in each teaspoonful dose? a. 10mg b. 12mg c. 15mg d. 20mg - Solution c. 15mg The usual dose of digoxin for rapid digitalization is a total of 1.0mg, divide into two or more portion at intervals of 6 to 8 hours. How many milliliters of digoxin elixir containing 50mcg/mL would provide this dose? a. 15mL b. 10mL c.25mL d.20mL - Solution d.20mL
The pediatric dose of cefadroxil is 30mg/kg/day. If a child was given a daily dose of 2 teaspoonfuls of pediatric suspension containing 125mg of cefadroxil per 5mL, what was the weight, in pounds of the child? a. 19lbs b. 17.3lbs c. 18.3lbs d. 18.5lbs - Solution c. 18.3lbs An antacid tablet contains 80mg of dried aluminum hydroxide gel and 20g of magnesium trisilicate. How many kilograms of aluminum hydroxide gel are required to manufacture 250000 bottles of the product, each containing 100 tablets? a.2000kg b.20000kg c.200kg d.8000kg - Solution a.2000kg A ferrous sulfate syrup contains 220mg of FeSO4.7H2O per teaspoon dose. How many milligrams of elemental iron are present in the dose? (mol wt FeSO4.7H2O= 278; at wt of Fe=55.9, S=32.1, O=16, H=1.0) a. 44mg b. 50mg c. 88mg d. 100mg - Solution a. 44mg An estradiol transdermal system contains in each skin patch 4mg of estradiol and 0.3mL of alcohol. How many liters of alcohol would be required to manufacture a half-million patches? a. 15L b. 150L c. 1500L d. 300L - Solution b. 150L From the ff formula: Benzyl benzoate 250mL Triethanolamine 5mL Purified water, to make 1000mL Calculate the quantity of benzyl benzoate required to make 6fl.Oz of benzyl benzoate lotion a.45mL
b. 40mL c. 4.5mL d. 25mL - Solution a.45mL If 10mL of a nitroglycerin injection (5mg of nitroglycerin per milliliter) are added to make a liter of intravenous fluid, what is the percentage (w/v) of nitroglycerin in the final product? a. 0.025% b. 0.05% c. 0.005% d. 0.0005% - Solution c. 0.005% If an intravenous dose of mannitol is 1.5% (w/v) sodium chloride solution can be made from 1 lb of sodium chloride? a. 50,444 mL b. 30,000 mL c. 50, 400 mL d. 1,000 mL - Solution b. 30,000 mL if a pharmacist dissolves the contents of 8 capsules, each containing 250mg of clindamycin hydrochloride, into a sufficient amount of lonex astringent to prepare 120mL of the solution, what is the percentage strength (w/v) of clindamycin hydrochloride in the prescription? a. 1% b. 1.5% c. 1.67% d. 2% - Solution c. 1.67% A formula for a mouth rinse contains 1/10% (w/v) of zinc chloride. How many grams of zinc chloride should be used in preparing 25 liters of the mouth rinse? a. 35g b. 30g c.20g d. 25g - Solution d. 25g Cocoa butter, which is solid at room temperature and melts at 34°C, has a specific gravity of 0.86. If a formula calls for 48mL of theobroma oil, what would be the corresponding weight of cocoa butter to use? a. 40g
A vaginal foam contains 0.01% (w/v) of dienestrol. Express this concentration as a ration strength. a. 1: b. 1:1, c. 1:1,000,000, d. 1:10,000 - Solution b. 1:1, A sample of white petrolatum contains 10mg of tocopherol per kilogram as a preservative. Express the amount of tocopherol as a ratio strength. a. 1:100, b. 1:1, c. 1:1,000, d. 1:10,000 - Solution a. 1:100, Hepatitis B immune globulin is preserved with 1:10,000 w/v of thimerosal. If the dose of the injection is 0.06 mL/Kg of body weight, how many micrograms of thimerosal would be contained in the dose for a 150-lb patient? a. 400mcg b. 409mcg c. 415 mcg d. 450mcg - Solution b. 409mcg If a serum sample is determined to contain 270mg/dL of cholesterol, what is the concentration of cholesterol (mol wt 386) in terms of millimoles per liter? a. 6.5mmol/L b. 6.9mmol/L c. 69.9mmol/L d. 5.66mmol/L - Solution b. 6.9mmol/L What is the percent concentration of cholesterol in a patient's blood serum if the cholesterol level is determined to be 260mg %? a. 2.6% b. 26% c. 0.26% d. 0.026% - Solution c. 0.26% If 250mL of a 1:800 (v/v) solution are diluted to 1000mL, what will be the ration strength (v/v)
a. 1: b. 1: c. 1: d. 1:32000 - Solution c. 1: A glucose meter shows that a patient's blood contains 125mg% of glucose. Express this value as mg/mL. a. 1.25mg/mL b. 12.5mg/mL c. 125mg/mL d. 0.125mg/mL - Solution a. 1.25mg/mL If 400mL of a 20% (w/v) solution are diluted to 2 Liters what will be the percentage strength w/v? a. 8% b. 4% c.5% d. 2% - Solution b. 4% How many milliliters of water must be added to 250mL of a 25% (w/v) stock solution of sodium chloride to prepare a 0.9% w/v sodium chloride solution? a. 65100mL b. 6600mL c. 6694mL d. 6490mL - Solution c. 6694mL How many milliliters of a syrup containing 85% w/v of sucrose should be mix with 150mL of a syrup containing 60% w/v of sucrose to make a syrup containing 80% (w/v) of sucrose? a. 500mL b. 550mL c. 600mL d. 650mL - Solution c. 600mL How many milliliters of 95% (w/w) sulfuric acid having a specific gravity of 1.820 should be used in preparing 2liters of 10% (w/v) sulfuric acid? a. 110mL b. 120mL c. 114mL d. 116mL - Solution d. 116mL
How many milliliters of a 23.5% (w/v) concentrate of sodium chloride solution should be used in preparing 650 mL of a stock solution such that 30 mL diluted to a liter will yield a 1:5000 solution? a. 0.2 mL b. 4.33 mL c. 18.44 mL d. 11.75 mL - Solution c. 18.44 mL A 35-mL aliquot was obtained from a mixture of 98% unknown solution. If half the sample is diluted to 100 mL, what is its final concentration? a. 17.15% b. 2.94% c. 280.0% d. 34.3% - Solution a. 17.15% Prepare 30% alcohol cooling sponge from 1 pint of 70% isopropyl rubbing alcohol using the whole bottle. a. add 500 mL of distilled water to 1 pt of 70% alcohol b. add 656.6 mL of distilled water to 1 pt of 70% alcohol c. add 333.33 mL of distilled water to 1 pt of 70% alcohol d. add 200 mL of distilled water to 1 pt of 70% alcohol - Solution b. add 656.6 mL of distilled water to 1 pt of 70% alcohol Rx Procaine hydrochloride 1% Sodium chloride q.s. Sterile water for injection add 100. Make isoton. Sol. Sig. for injection How many grams of sodium chloride should be used in compounding the prescription? (NaCl equivalent of procaine HCl is 0.21) a. 0.690 g b. 0.5 g c. 0.6 g d. 0.65 g - Solution a. 0.690 g Calculate the sodium (Na) content, in terms of mEq, of 1 g of ampicillin sodium (C16H18N3NaO4S, mol wt 371) a. 2.5 mEq b. 2.8 mEq
c. 2.7 mEq d. 3 mEq - Solution c. 2.7 mEq What is the concentration, in milligrams per milliliter, of a solution containing 5 mEq of potassium chloride (KCl) per milliliter? a. 372.5 mg b. 375 mg c. 370 mg d. 368.5 mg - Solution a. 372.5 mg Ammonium chloride (NH4Cl, mol wt 53.5) is to be used as a urinary acidifier with a dose of 150 mEq. How many 500 mg tablets should be administered? a. 16 tablets b. 20 tablets c. 15 tablets d. 13 tablets - Solution a. 16 tablets Give anti-diphtheria serum 6000 U by intramuscular 2injections to a patient. The patient stock is 10000 U/5mL vial. How many mL are you going to inject? a. 3 mL b. 5 mL c. 2 mL d. 1 mL - Solution a. 3 mL A physician places a patient on a daily dose of 60 units of u-80 units' insulin. How many ml should the patient inject each day? a. 0. b. 1. c. 0. d. 0.5 - Solution a. 0. A jar of cleansing cream is sold for P7.50, thereby yielding a gross profit of 60% on the cost. What did it cost? a. P5. b. P4. c. P4. d. P4.50 - Solution c. P4.
b. 1: c. 1: d. 1:3 - Solution d. 1: A formula for a dermatologic cream calls for a 15 g of an emulsifier blend consisting of Tween 20 and Span 40. If the required HLB is 11.70, how many grams of each emulsifier should be used in emulsifying the cream? (HLB of Tween 20 is 16.7 and Span 40 is 6.7) a. 5 g Tween 20 and 10 g Span 40 b. 7.5 g Tween 20 and 7.5 g Span 40 c. 2.5 g Tween 20 and 12.5 g Span 40 d. none of the above - Solution b. 7.5 g Tween 20 and 7.5 g Span 40 How many 1- fluid ounce bottles of lagundi syrup can be prepared from 5 gallons of syrup? a. 740 b. 640 c. 639 d. 540 - Solution b. 640 A formula for cough syrup contains 1/8 grain of codeine phosphate per teaspoonful. How many grams of codeine phosphate should be used to prepare a quart of cough syrup? a. 1.75 g b. 1.54 g c. 1.84 g d. 2.54 g - Solution b. 1.54 g The inhalant dose of amyl nitrite is 0.18mL. Express the dose in minims. a. 4m b. 2m c. 3m d. 5m - Solution c. 3m A patient weighing 8lbs is prescribed 2mEq/kg/day of potassium chloride (mol wt 74.5). How many mg of potassium chloride will be administered to the patient per day? a. 541. b. 538 c. 436.
d. 648 - Solution a. 541. How many grams of sodium chloride (mol wt 58.5) should be used to prepare 1 gallon of an isotonic solution? a. 24 b. 28 c. 32 d. 34.1 - Solution d. 34. A sterile solution of potassium chloride (mol wt 74.5) contains 2 mEq/mL. If a 20 mL ampoule of the solution is diluted to 1 liter, what is the percentage strength of the resulting solution? a. 0. b. 0. c. 1. d. 0.3241 - Solution a. 0. How many milliliters of a 3% (w/v) solution of ammonium chloride (mol wt 53.5) should be administered intravenously to provide 50 mEq? a. 99. b. 89. c. 69. d. 79.2 - Solution b. 89. An initial dose of not less than 150 units/kg of body weight has been recommended for open heart surgery. How many mL of an injection containing 5000 heparin units per mL should be administered to a 300 lb patient? a. 4.1 mL b. 4.1microliter c. 5.1 mL d. 5.1microliter - Solution a. 4.1 mL Acetazolamide sodium is available in 500mg vials to be reconstituted to 5 mL with sterile water for injection prior to use. The dose of the drug for children is 5 mg/kg of body weight. How many mL of the injection should be administered to a child weighing 25lbs? a. 0.57 mL b. 0.52 mL c. 0.50 mL
c. 42. d. 60.2 - Solution b. 62. If 500 mL of mineral oil which has a specific gravity f 0.87, is used to prepare 2 pints of mineral oil emulsion, how many grams of the oil would be used to prepare 1 gallon of the emulsion? a. 1740. b. 1430. c.1750. d. 1741.4 - Solution a. 1740. A perfume oil has a specific gravity of 0.960 and costs P776.25 per kg. How much would 5 fluidounces cost? a. P110. b. P111. c. P109. d. P180.15 - Solution a. P110. If 800 g of a 5% coal tar ointment is mixed with 1200 g of a 10% coal tar ointment, what is the concentration of coal tar in the finished product? a. 8% b. 8.5% c. 9% d. 9.5% - Solution a. 8% How many mL of a 5% (w/v) solution of lidocaine hydrochloride should be used in preparing 500 mL of a solution containing 25 mg of lidocaine hydrochloride per mL solution? a. 250 mL b. 260 mL c. 240 mL d. 270 mL - Solution a. 250 mL In what proportion should 10% and 2% coal tar ointments be mixed to prepare a 5% ointment? a. 3: b. 2: c. 3: d. 2:3 - Solution c. 3:
How many g of isoflurophate are contained in 15 g of a 1:10, ophthalmic solution of isoflurophate in peanut oil? a. 1.8 mg b. 1.9 mg c. 1.7 mg d. 1.5 mg - Solution d. 1.5 mg The normal range of specific gravity of urine is about 1.003 to 1.030. Using 5 mL urine samples, what would be the difference in weight, in mg, between these extremes? a. 145 mg b. 135 mg c. 136 mg d. 155 mg - Solution b. 135 mg What is the single dose for a child weighing 53 lbs if the usual pediatric dose of cefazolin sodium is 25 mg/kg/day divided equally into 3 doses? a. 200 mg b. 210 mg c. 200 g d. 220 mg - Solution a. 200 mg The adult dose of a liquid medication is 0.1 mL/kg body weight to be administered as a single dose. How many teaspoonfuls should be given to a patient weighing 220 lb? a. 2tsp b. 2.5 tsp c.3 tsp d. 2 tbsp - Solution a. 2tsp What is the dose of a drug for a 6-year old child if the average adult dose is 1 ½ grains? a. ½ g b. ½ gr c. ½ mg d. ½ mcg - Solution b. ½ gr If 250 units of an antibiotic weighs 1 mg, how many units are in 25 mg? a. 6, b. 6,
