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Pathology University Questions, Exams of Pathology

SRM Institute Of Science & TechnologyPathology

This document includes a compiled list of all the important questions related to every topic in Pathology subject, these include all the previously asked questions. It is very helpful to cover Pathology syllabus in a short amount of time as well as to revise through the whole year’s syllabus. This is a very helpful list of questions to ace your University Examinations for 2nd Year MBBS. All the questions have complied in accordance with the book “Robbins & Cotran Pathologic Basis of Disease” which is considered standard in MBBS course.

Typology: Exams

2024/2025

Available from 07/05/2025

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II Year University Questions
Pathology
SRI NALABOLU
PAPER 1 (14 essays 70 short notes)
I. GENERAL PATHOLOGY
A. Essay
1. Necrosis: Etiopathogenesis, morphological variants and clinical implications of necrosis
2. Apoptosis: molecular mechanism, and tabulate apoptosis vs necrosis
3. Define amyloid, write its chemical nature and morphology of amyloidosis
4. Edema: define, classify. Write the pathogenesis of general edema. Write the
complications of renal deem
5. Define Shock. Write the types. Write the pathogenesis of septic shock, stages of septic
shock and morphological changes in various organs in shock.
6. ***Define Thrombosis. Write the pathogenesis of thrombosis, its morphology and fate
of thrombus.
7. Define inflammation. Write the role of chemical mediators of acute inflammation
8. Wound healing and fractures. What is the healing process in long bone fracture. Define
Repair and factors influencing wound healing. Write the types of wound healing.
9. ***Neoplasia: define using the Willi’s definition. Differentiate between benign and
malignant tumours. Write on chemical carcinogens. Give examples. Write their
mechanisms. What are the characteristics of malignant. What is the ways in which
tumours spread to other places (routes of spread)
B. Short Notes
1. Haemosiderosis
2. Haemochromatosis
3. Caseous necrosis
4. Mechanism of apoptosis
5. Difference between necrosis and apoptisis
6. Gangrene
7. Pathological calcification
8. Matastatic calcification
9. Metaplasia
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PAPER 1 (14 essays 70 short notes)

I. GENERAL PATHOLOGY

A. Essay

  1. Necrosis: Etiopathogenesis, morphological variants and clinical implications of necrosis
  2. Apoptosis: molecular mechanism, and tabulate apoptosis vs necrosis
  3. Define amyloid, write its chemical nature and morphology of amyloidosis
  4. Edema: define, classify. Write the pathogenesis of general edema. Write the complications of renal deem
  5. Define Shock. Write the types. Write the pathogenesis of septic shock, stages of septic shock and morphological changes in various organs in shock.
  6. ***Define Thrombosis. Write the pathogenesis of thrombosis, its morphology and fate of thrombus.
  7. Define inflammation. Write the role of chemical mediators of acute inflammation
  8. Wound healing and fractures. What is the healing process in long bone fracture. Define Repair and factors influencing wound healing. Write the types of wound healing.
  9. ***Neoplasia: define using the Willi’s definition. Differentiate between benign and malignant tumours. Write on chemical carcinogens. Give examples. Write their mechanisms. What are the characteristics of malignant. What is the ways in which tumours spread to other places (routes of spread) B. Short Notes
  10. Haemosiderosis
  11. Haemochromatosis
  12. Caseous necrosis
  13. Mechanism of apoptosis
  14. Difference between necrosis and apoptisis
  15. Gangrene
  16. Pathological calcification
  17. Matastatic calcification
  18. Metaplasia
  1. Type I hypersensitivity
  2. Type 4 hypersensitivity
  3. Amyloidosis morphology
  4. Pathogenesis of renal edema
  5. Edema classification, MOA of formation of edema
  6. CVS liver
  7. Shock: types, pathogenesis of sept shock
  8. Air embolism
  9. Acute inflammation - cellular events that take place
  10. Cell adhesion molecules
  11. Chemotaxis
  12. Phagocytosis
  13. Chemical mediators
  14. Granuloma
  15. Ghons complex: pathogenesis and common sites
  16. Leprosy - morbid anatomy and lepromatous leprosy
  17. Wound healing complications and factors that influence it
  18. Teratoma
  19. Fibroadenoma
  20. Metastasis
  21. Grading and staging of cancer
  22. Chemical carcinogenesis
  23. Radiation oncogenesis
  24. Viral carcinogenesis
  25. Lab diagnosis of cancer
  26. Tumour markers
  27. Vitamin A deficiency
  28. Rickets
  29. Downs syndrome
  30. Gauchers disease
  31. Difference between benign and malignant tumours II. HEMATOLOGY
  1. CML blood picture and bone marrow picture
  2. Lab diagnosis of CLL
  3. Multiple myeloma (blood picture and bone marrow picture, lab diagnosis)
  4. Hodgkins lymphoma (types and morphology)
  5. Cytochemistry in acute leukaemia
  6. Reed Sternberg cell
  7. Myelodysplastic syndrome
  8. BCC
  9. Lab diagnosis of pyogenic meningitis

PAPER 2 (20 essays 77 short notes)

I. SYSTEMIC PATHOLOGY

A. Blood Vessels and lymphatics

1. Essay a) Define Atherosclerosis. Write the etiopathogenesis, morphology, risk factors and complications involved. 2. Short Notes a) Atherosclerosis b) Aneurysm aorta **B. Heart and CVS

  1. Essay** a) What is Myocardial infarction. Write the Etiopathogenesis, lab diagnosis, morphological changes, reaction to time and complications b) What are the features of rheumatic fever. What is rheumatic heart disease. Write the etiopathogenesis, morphology and complications involved**.
  2. Short Notes** a) Lab diagnosis of MI b) Aschoff body c) Acute infective endocarditis - causative organism, morphology and complications d) What are the vegetations of heart **C. RS
  3. Essay** a) COPD Etiopathogenesis and types b) Emphysema: etiopathogenesis, types and morphology—classify emphysema and write its pathogenesis 2. Short Notes a) Classification of pneumonia b) Lobar pneumonia and its stages c) Classification of emphysema and pathogenesis d) Bronchiectasis

G. Livery, biliary tract and exocrine pancreas

1. Essay a) Cirrhosis : classify, pathogenesis of portal cirrhosis. Etiopathogenesis, morphology, clinical symptoms and investigations and complications of alcoholic cirrhosis 2. Short Notes a) Liver changes in viral hepatitis b) Alcoholic liver diseases c) Cirrhosis - histopathogenesis d) Alcoholic hepatitis e) Histopathogenesis f) Hemochrombtosis g) Hepatic cysts - write the differential diagnosis by lab methods h) Hepatocellular carcinoma i) Gall stones - write the pathogenesis and types **H. Renal and Lower Urinary tract

  1. Essay** a) Nephritic Syndrome: Write the ethology and write one of the causative conditions, pathogenesis and lab diagnosis b) Nephrotic syndrome: write ints causes and etiopathogenesis, and pathology of minimal change disease c) RPGN: write its clinical features, gross and microscopic study. Write the lab diagnosis d) Write Acute proliferative glomerulonephritis. Etiopathogenesis, pathology and urinary findings e) Type I DM. Write its pathogenesis and morphology of diabetic nephropathy 2. Short Notes a) Polycystic kidney disease b) RPGN c) Pyelonephritis (acute and predisposing factors) d) Chronic pyelonephritis e) Renal Stones f) Renal Cell carcinoma

g) Wilms tumour h) PUNLUMP (papillary urothelial neoplasms of unknown malignant potential) I. Female Genital Tract

1. Essay: a) CA cervic : etiopathogenesis and pathology b) Ovarian neoplasm. Write its morphology of germ cell tumours. 2. Short Notes a) CIN b) Lab diagnosis of early and pre early cancerous lesions of uterine cervic c) Endometriosis d) Dermoid cyst of the ovary e) Dysgerminoma f) Hydatidiform mole (pathogenesis of vesicular mole) J. Male Reproductive system and prostate (SN only) a) Seminoma (gross and microscopy) **K. Breast

  1. Essay (case)** a) 50 y. Fixed immobile lump in the left upper quadrant of breast. Write the diagnosis, etiopathogenesis and classification. What is the morpohological common type 2. Short Notes a) Fibrocystic disease of breast b) Fibroadenoma of breast c) Classification of breast tumours d) Pages disease of breast e) Triple negative breast tumours **L. Skin
  2. Essay** a) Malignant melanoma - write its pathology, clinical features and course 2. Short Notes