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PATHOLOGY NBME EXAMS | ALL QUESTIONS AND CORRECT ANSWERS (ALREADY GRADED A+) | LATEST VERSION | VERIFIED ANSWERS 2025
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CLL is a B-cell malignancy and smudge cells are fragile B cells on smear.
B12 deficiency impairs DNA synthesis, causing megaloblastic anemia and neuro symptoms.
Systemic lupus erythematosus RBC casts + lupus serologies suggest lupus nephritis.
Small cell carcinoma Neuroendocrine tumor with fine chromatin and rapid growth.
WT1 gene mutation WT1 is a tumor suppressor gene on chromosome 11p13, commonly mutated in Wilms tumor.
Increased estrogen levels Liver cannot degrade estrogens, leading to feminization.
IgA nephropathy (Berger disease) Presents soon after mucosal infection with IgA deposition in mesangium.
Granulosa cell tumor Estrogen-secreting tumor with coffee-bean nuclei and Call-Exner bodies.