Passive Immunisation
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Passive Immunization: Modes, Natural, Artificial, and Immunoglobulins, Slides of Microbiology
An overview of passive immunization, a type of immunization that involves administering antibody-containing serum for immediate, temporary protection against infectious diseases. Natural and artificial sources of passive immunization, as well as the types of immunoglobulins used for this purpose. Topics include diphtheria, tetanus, streptococcus, rubeola (red measles), rubella (german measles), mumps, polio, hepatitis a, parvovirus, enterovirus infections, hiv, zoster, rabies, and hbv.
Typology: Slides
2012/2013
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Passive Immunisation
Modes of immunization
- Passive immunization - administration of antibody- containing serum to provide immediate, but temporary protection. Doesn't activate a lasting specific immune response.
Artificial
- Often used as antitoxins for things such as black widow spider and snake bites, botulism, and tetanus. Important for some infectious diseases such as rabies, since it provides immediate protection rather than waiting the 7-10 days for a protective response to develop from active immunization.
Immunoglobulin
- “ Normal”Immune globulin
- Hyper-immune globulin
Hyper-immune globulin
--- high titres of antibody to particular viruses
- Zoster immune globulin: prevention of varicella in immunocompromised children and neonates
- Human rabies immunoglobulin: post-exposure prophylaxis in an individual who has been bitten by a rabid animal
- Hepatitis B immune globulin:non-immune individal who has been exposed to HBV
- RSV immune globulin: treatment of respiratory syncitial virus infections in the very young