Docsity
Log inSign up
Docsity
Prepare for your exams
Prepare for your exams

Study with the several resources on Docsity

Earn points to download
Earn points to download

Earn points by helping other students or get them with a premium plan

Guidelines and tips
Guidelines and tips
Sell on Docsity
Sell on Docsity
Log inSign up

Prepare for your exams

Study with the several resources on Docsity

Find documents

Prepare for your exams with the study notes shared by other students like you on Docsity

Search Store documents

The best documents sold by students who completed their studies

Search through all study resources
Docsity AINEW

Summarize your documents, ask them questions, convert them into quizzes and concept maps

Explore questions

Clear up your doubts by reading the answers to questions asked by your fellow students

Earn points to download

Earn points by helping other students or get them with a premium plan

Share documents
download point icon20 Points

For each uploaded document

Answer questions
download point icon5 Points

For each given answer (max 1 per day)

All the ways to get free points
Get points immediately

Choose a premium plan with all the points you need

Study Opportunities

Choose your next study program

Get in touch with the best universities in the world. Search through thousands of universities and official partners

Community

Ask the community

Ask the community for help and clear up your study doubts

University Rankings

Discover the best universities in your country according to Docsity users

Free resources

Our save-the-student-ebooks!

Download our free guides on studying techniques, anxiety management strategies, and thesis advice from Docsity tutors

From our blog

Exams and Study
Go to the blog

Amlodipine Tablets: Uses, Dosage, Side Effects, and Precautions, Study notes of Medicine

Accrington and Rossendale CollegeMedicine

Information about Amlodipine tablets, their uses, dosage, side effects, and precautions. Amlodipine is a calcium antagonist used to treat high blood pressure and chest pain. Learn about its warnings, interactions, and storage instructions.

Typology: Study notes

2021/2022

Uploaded on 09/12/2022

ronyx
ronyx 🇬🇧

4

(4)

213 documents

1 / 7

Toggle sidebar

This page cannot be seen from the preview

Don't miss anything!

bg1
PACKAGE LEAFLET: INFORMATION FOR THE USER
Amlodipine 5 mg Tablets
Amlodipine 10 mg Tablets
(Amlodipine Besilate)
Read all of this leaflet carefully before you start taking this medicine because it
contains important information for you.
- Keep this leaflet. You may need to read it again.
- If you have any further questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you only. Do not pass it on to others. It
may harm them, even if their symptoms are the same as yours.
- If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any
possible side effects not listed in this leaflet. See section 4.
What is in this leaflet:
1. What Amlodipine tablets are and what they are used for
2. What you need to know before you take Amlodipine tablets
3. How to take Amlodipine tablets
4. Possible side effects
5. How to store Amlodipine tablets
6. Contents of the pack and other information
1. What Amlodipine tablets are and what they are used for
Amlodipine tablets belongs to a group of medicines called calcium antagonists.
Amlodipine tablets are used to treat:
- high blood pressure (hypertension)
- chest pain due to narrowing of the blood vessels of the heart muscle (angina pectoris)
or the more rare form of chest pain caused by cramping of the blood vessels of the
heart muscle called Prinzmetal or variant angina.
If you suffer from high blood pressure, Amlodipine works by relaxing blood vessels, so
that blood passes through them more easily.
If you suffer from angina, Amlodipine works by improving blood supply to the heart
muscle which then receives more oxygen and as a result chest pain is prevented.
Amlodipine does not provide immediate relief of chest pain from angina.
2. What you need to know before you take Amlodipine tablets
Do not take Amlodipine tablets, if you
- are allergic (hypersensitive) to amlodipine or any of the other ingredients of this
medicine listed in section 6, or to any other calcium antagonists (the so-called
dihydropyridine derivates like felodipine, nifedipine, nimodipine). This may be
itching, reddening of the skin or difficulty in breathing.
- are suffering from cardiogenic shock. This is a condition where the heart is unable
to pump sufficient blood around the body. The symptoms of cardiogenic shock are low
pf3
pf4
pf5

Partial preview of the text

Download Amlodipine Tablets: Uses, Dosage, Side Effects, and Precautions and more Study notes Medicine in PDF only on Docsity!

PACKAGE LEAFLET: INFORMATION FOR THE USER

Amlodipine 5 mg Tablets Amlodipine 10 mg Tablets (Amlodipine Besilate) Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet. You may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
  • If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. See section 4. What is in this leaflet:
  1. What Amlodipine tablets are and what they are used for
  2. What you need to know before you take Amlodipine tablets
  3. How to take Amlodipine tablets
  4. Possible side effects
  5. How to store Amlodipine tablets
  6. Contents of the pack and other information 1. What Amlodipine tablets are and what they are used for Amlodipine tablets belongs to a group of medicines called calcium antagonists. Amlodipine tablets are used to treat:
  • high blood pressure (hypertension)
  • chest pain due to narrowing of the blood vessels of the heart muscle (angina pectoris) or the more rare form of chest pain caused by cramping of the blood vessels of the heart muscle called Prinzmetal or variant angina. If you suffer from high blood pressure, Amlodipine works by relaxing blood vessels, so that blood passes through them more easily. If you suffer from angina, Amlodipine works by improving blood supply to the heart muscle which then receives more oxygen and as a result chest pain is prevented. Amlodipine does not provide immediate relief of chest pain from angina. 2. What you need to know before you take Amlodipine tablets Do not take Amlodipine tablets, if you
  • are allergic (hypersensitive) to amlodipine or any of the other ingredients of this medicine listed in section 6, or to any other calcium antagonists (the so-called dihydropyridine derivates like felodipine, nifedipine, nimodipine). This may be itching, reddening of the skin or difficulty in breathing.
  • are suffering from cardiogenic shock. This is a condition where the heart is unable to pump sufficient blood around the body. The symptoms of cardiogenic shock are low

blood pressure, low pulse and fast heartbeat.

  • are suffering from narrowing of the aortic heart valve ( aortic stenosis ) or cardiogenic shock (a condition where your heart is unable to supply enough blood to the body) or if you suffer from heart failure after a heart attack.
  • suffer from chest pain at rest or with minimal effort ( unstable angina pectoris ).
  • are pregnant or breast-feeding.
  • have severe low blood pressure (hypotension). Warnings and precautions Before taking Amlodipine tablets, tell your doctor if you
  • have heart failure or have suffered a heart attack during the past month.
  • Heart failure
  • Severe increase in blood pressure (Hypertensive crisis)
  • have liver problems
  • are giving this medicine to a child under 18 years of age
  • are elderly , your doctor may monitor you closely. Children and adolescents Amlodipine has not been studied in children under the age of 6 years. Amlodipine should only be used for hypertension in children and adolescents from 6 years to 17 years of age (see section 3). For more information, talk to your doctor. Other medicines and Amlodipine tablets Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Some medicines (including medicines obtained without prescription, herbal medications or natural products) may interact with Amlodipine. This means that the action of both medicines can be changed. In particular, tell your doctor if you are taking any of the following medicines:
  • Medicines that can lower blood pressure (e.g. verapamil, diltiazem)
  • Ketoconazole and itraconazole (antifungal medicines used to treat skin and fungal infections)
  • HIV-protease-inhibitors (antiviral medicines used to treat HIV infections, e.g. ritonavir )
  • Clarithromycin , erythromycin and telithromycin , rifampicin , rifabutin (antibiotics)
  • Nefazodone (medicine to treat depression)
  • St. John’s wort (Hypericum perforatum; herbal medicine for depression)
  • Dexamethasone (corticosteroid used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis)
  • verapamil, diltiazem (heart medicines)
  • dantrolene (infusion for severe body temperature abnormalities)
  • tacrolimus (medicine used to alter the way your immune system works)
  • simvastatin (cholesterol lowering medicine)
  • cyclosporine (an immunosuppressant)
  • Phenobarbital , phenytoin and carbamazepin (medicines for epilepsy)

Adults The usual starting dose is 5 mg once daily. If necessary, your doctor may increase the dose to 10 mg once daily. Use in children and adolescents (6 - 17 years old) The recommended usual starting dose is 2.5 mg a day. The maximum recommended dose is 5 mg a day. It is important to keep taking the tablets. Do not wait until your tablets are finished before seeing your doctor. Amlodipine 2.5 mg is not currently available and the 2.5 mg dose cannot be obtained with Amlodipine tablets 5 mg and 10 mg as these tablets are not manufactured to break into two equal halves. Elderly patients There is no special dosage for the elderly; however, care must be taken when the dose is increased. If you have kidney problems The normal dosage is recommended. Amlodipine cannot be removed from the blood by dialysis (artificial kidney). Amlodipine tablets should be administered with particular caution to patients undergoing dialysis. If you have liver problems Your doctor will decide if this medicine is suitable for you and the correct dose for you to take. If you take more Amlodipine tablets than you should If you or someone else has taken too much Amlodipine, contact your nearest hospital casualty department. Please carry with you the product leaflet or remaining tablets for better identification of the doctor. The person concerned should be made to lie down with their arms and legs up (resting on a couple of cushions, for example). Symptoms of an overdose are: extreme dizziness and/or feeling very light-headed, faint or weak, problems with breathing, having to urinate very often. If blood pressure drop is severe enough shock can occur. Your skin could feel cool and clammy and you could lose consciousness. If you forget to take Amlodipine tablets Do not worry. If you forget to take a tablet, leave out that dose completely. Take your next dose at the right time. Do not take a double dose to make up for a forgotten dose. If you stop taking Amlodipine tablets Your doctor will advise you how long to take this medicine. Your condition may return if you stop using this medicine before you are advised. If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, Amlodipine tablets can cause side effects, although not everybody gets them. Tell your doctor immediately if you experience any of the following symptoms after taking this medicine. Although they are very rare, the symptoms can be severe.

  • Sudden wheeziness, chest pain, shortness of breath or difficulty in breathing
  • Swelling of eyelids, face or lips
  • Swelling of the tongue and throat which causes great difficulty breathing
  • Severe skin reactions including intense skin rash, hives, reddening of the skin over your whole body, severe itching, blistering, peeling and swelling of the skin, inflammation of mucous membranes (Stevens Johnson Syndrome) toxic epidermal necrolysis or other allergic reactions
  • Heart attack, abnormal heart beat
  • Inflamed pancreas which may cause severe abdominal and back pain accompanied with feeling very unwell The following very common side effect has been reported. If this causes you problems or if it lasts for more than one week , you should contact your doctor. Very common (may affect more than 1 in 10 people)
  • Oedema (fluid retention) The following common side effects have been reported. If any of these cause you problems or if they last for more than one week , you should contact your doctor. Common (may affect up to 1 in 10 people)
  • Headache, dizziness, sleepiness (especially at the beginning of treatment)
  • Palpitations (awareness of your heart beat),flushing
  • Abdominal pain, feeling sick(nausea)
  • Altered bowel habits, diarrhoea, constipation, indigestion,
  • Tiredness, weakness
  • Visual disturbances, double vision
  • Muscle cramps
  • Swollen ankles Other side effects that have been reported include the following list. If any of these get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. Uncommon (may affect up to 1 in 100 people)
  • Enlarged breasts or discomfort in men
  • Sleep disorders, irritability, depression
  • Pain, feeling unwell, dry mouth, uncontrolled shaking, pins and needles, increased sweating
  • Problems with your eye-sight (visual disturbances)
  • Mood changes, anxiety, depression, sleeplessness
  • Trembling, taste abnormalities
  • Numbness or tingling sensation in your limbs, loss of pain sensation
  • Sneezing/running nose caused by inflammation of the lining of the nose (rhinitis)

environment.

6. Contents of the pack and other information What Amlodipine tablet contains - The active substance is amlodipine. Each tablet contains either 5 mg or 10 mg of amlodipine (as besilate). - The other ingredients are microcrystalline cellulose (E460), sodium starch glycollate, sodium acid citrate (E331), magnesium stearate (E572), croscarmellose sodium and crospovidone. What Amlodipine tablets look like and contents of the pack Amlodipine 5 mg and 10 mg tablets are white to off-white, circular, biconvex, uncoated tablets plain on both sides. Amlodipine tablets are available in blister pack of 28 tablets. Bottle packs: 250, 500 and 1000 tablets (for hospital or dose dispensing use only) Not all pack sizes may be marketed. Marketing Authorisation Holder and Manufacturer Accord Healthcare Limited Sage House, 319 Pinner Road, North Harrow, Middlesex, HA1 4HF, United Kingdom This leaflet was last revised in 07 /202 1.