Chemistry 501
Handout 19
Oxidative Phosphorylation and Photophosphorylation
Chapter 19
Dep. of Chemistry & Biochemistry
Prof. Indig
Lehninger. Principles of Biochemistry.
by Nelson and Cox, 5th Edition; W.H. Freeman and Company
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Exploring Oxidative & Photophosphorylation: Respiratory Chain & ATP Synthesis, Study notes of Chemistry
This handout from chemistry 501 covers the essential concepts of oxidative phosphorylation and photophosphorylation, focusing on the biochemical anatomy of a mitochondrion, the separation of functional complexes in the respiratory chain, and the generation of atp through the chemiosmotic model. Topics include nadh dehydrogenase (complex i), succinate dehydrogenase (complex ii), ubiquinone cytochrome c oxidoreductase (complex iii), cytochrome oxidase (complex iv), the q cycle, proton-motive force, and mitochondrial atp synthase complex.
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Chemistry 501
Handout 19
Oxidative Phosphorylation and Photophosphorylation
Chapter 19
Dep. of Chemistry & Biochemistry Prof. Indig Lehni nger. Principles of Biochemistry. by Nelson and Cox, 5 th Edition; W.H. Freeman and Company
Biochemical anatomy of a mitochondrion
Separation of functional complexes
of the respiratory chain
Succinate dehydrogenase (complex II)
Ubiquinone cytochrome c oxidoreductase (complex III) (Cytochrome bc 1 complex)
Cytochrome oxidase (complex IV)
Summary of the flow of electrons and protons through the four complexes of the respiratory chain
Chemiosmotic model
Mitochondrial ATP synthase complex Binding-change model for ATP synthase
Adenine nucleotide and phosphate translocases