NURS 5334 PHARM FINAL EXAM 2025 VERIFIED QUESTIONS AND ANSWERS, Exams of Nursing

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• NURS 5334 PHARM FINAL EXAM

What are three drugs that can be combined with Hydrocodone? (PainManagement Mod 3) - ANSWERAspirin Acetaminophen Ibuprofen Benzodiazepines and CNS depressants can be paired with acetaminophen-hydrocodone, True or False? - ANSWERFalse, this could lead to respiratory depression Why would you give a patient Buprenorphine for maintenance once theyrecovered from opioid abuse? - ANSWERPartial opioid agonist that activated opioid receptors but produces less degree of euphoria and physical dependencecompared to a full agonist

Why would you give a patient Naltrexone for maintenance once they recoveredfrom opioid abuse? - ANSWERNaltrexone is a opioid antagonist that blocks the euphoric and sedative effects of opioids. What are 3 side effects of Hydrocodone? - ANSWERConstipation Respiratorydepression Addition What's the MOA of Sumatriptan? (-triptan) - ANSWERSelective agonist forserotonin 5HT receptors on intracranial blood vessels and sensory nerves of the trigeminal system, causes VASOCONSTRICTION and reduces neurogenicinflammation

What is the supplement Feverfew used for? - ANSWERMigraine Prophylaxis

What are the names of two medications that are safe for pregnant women? -ANSWERMethyldopa and Labetalol are the traditional agents of choice for pregnant women Why can Methyldopa and Labetalol be used in pregnant women? - ANSWERThesedrugs have limited effects on uteroplacental and fetal Hemodynamics and do not adversing effect the fetus or neonate Anticholinergics such as Trihexyphenidyl and Benztropine can help with droolingin Parkinson's patients, True or False? - ANSWERTrue A patient with COPD comes in to the hospital for the second time for moderateexacerbation. The eosinophils are 312. What medication should this patient be on to manage symptoms? A. Salmeterol B.C. Formoteral + AlbuterolAlbuterol + Budesonide D.+ Budesonide Salmeterol + aclidinium + Budesonide - ANSWERD. Salmeterol + aclidinium

If Eosinophils are greater than or equal to 300, then you should consider aLABA+LAMA+ICS

COPD Group A - ANSWERBroncodilator COPD Group B - ANSWERLABA + LAMA

COPD Group E - ANSWERLABA + LAMA How does an increase percentage of body at effect the plasma level of lipidsoluble drugs in an elderly individual? - ANSWERThe higher the body fat percentage the more the plasma levels of lipid soluble drugs will be reduced A decrease in lean mass causes concentration of water soluble drugs to be(inc/dec) in elderly patients? - ANSWERIncreased

For elderly patients that are malnourished (low albumin level) free drug levels ofprotein binding drugs will (inc/dec)? - ANSWERIncrease

A child is about to get the Proquad Vaccine, which is a mix of the Varicella andMMR vaccine. What education would you need to give to the parents? - ANSWERDeposited getting the vaccine there is still a chance your child could getbreakthrough chickenpox

What is the starting dosage of thyroid medication for a in elderly patient that is 51with no comorbidities? - ANSWER50 mcg

What is the starting dosage of thyroid medication for an elderly patient that is 68years with no comorbidities? - ANSWER25 mcg

What is the dosage range for thyroid medication for a person with CAD? -ANSWER12- 25 mcg

What are the adverse effects of Haloperidol? - ANSWERExtrapyramidal SideEffects

What is the MOA of Chlorpromazine? - ANSWERBlocking dopamine D2 receptorsin the brain

What are extrapyramidal symptoms? - ANSWERDystonia Tardive dyskinesia Akathisia Pseudoparkinsonism What is the MOA of Second Generation antipsychotics? - ANSWERDopamine D2receptor antagonist and Serotonin 5-HT2A Receptor antagonist

What are the endings of Atypical Antipsychotics? - ANSWER-pine -idone-zole

Clozapine Risperidone Aripiprazole What is are some side effects of Clozapine? (4) - ANSWERAgranulocytosisDiabetes Dyslipidemia Weight Gain What medication is used to treatment of Tardive Dyskinesia? -ANSWERValbenazine followed by Deutetrabenazine

What foods need to be avoided while on Levadopa/Carbidopa? - ANSWERHighprotein diet needs to be avoided. High protein food can delay absorption

It's safe to take a lot of Vitamin A while pregnant, True or False? - ANSWERFalse,Vitamin A toxicity is Teratogenic

What are two signs of Vitamin A Toxicity? - ANSWERLiver injury Bone relateddisorders

Which antidepressant has the least amount of sexual side effects? -ANSWERBupropion

Nonpharmalogical Management of Gout - ANSWERLow Purine diet Joint restWeight Reduction Fluid intake of 3Liters

What is the first-line treatment for Gout? (Urage Lowering Therapy) -ANSWERAllopurinol

NSAIDS can be given to a patient with Rheumatoid Arthritis for pain andinflammation, True or False? - ANSWERTrue

Patients with Rheumatoid Arthritis should also be put on a DMARD to reduce jointdestruction, True or False? - ANSWERTrue

Which one of these medications are considered First-line treatment forRheumatoid Arthritis for Moderate to Severe disease?

What is the MOA of Fibrates? - ANSWERFibrates are intracellular receptors that regulate fat and carbohydrate metabolism. work by activating PPARα which Increase the breakdown of triglycerides into fatty acids via beta oxidation Name the Three Fibrates that help lower triglycerides? - ANSWERFenofibrateGemfibrozil Lovaza "FIBRATES For triGLycerdes " Fibrates have little effect on LDLs, True or False? - ANSWERTrue What two Statins are best for Hyperlipidemia? - ANSWERRosuvastatinAtorvastatin

What is needed for children with rickets for recovery? - ANSWERVitamin D What Foods would be suitable for chicken with Rickets for Vitamin D replacementtherapy? - ANSWERFortified Foods Cereals Milk Yogurt Margarine CheeseOrange Juice What is the therapeutic use of Feverfew? - ANSWERMigraine ProphylaxisWhat drugs are not able to be mixed with Feverfew? - ANSWERPatient has an increased risk of bleeding in patients taking Anticoagulants and Antiplatelets Antiplatelets (Aspirin) Anticoagulants (Warfarin)

What is the therapeutic use of Coenzyme Q-10? (3) - ANSWER1. Treat HeartFailure 2.3. Muscle Injury caused by HMG-CoA reductase inhibitors (Statins)Mitochondrial Encephalopathies (muscle and nervous system injury)

What is a side effect of CoQ-10? - ANSWERGI Disturbances What drug does CoQ-10 interact with? - ANSWERCoQ-10 is structurally similar toVitamin K and can have antagonizing effects on Warfarin

Name three side effects of Vitamin B12 deficiency? - ANSWER1. NeurologicDamage: Numbness and tingling in the hands and feet

2. Impaired production of white blood cells
3. GI Disturbances: impaired absorption What natural supplement can help with Osteoarthritis of the knees, hips, andwrists? - ANSWERGlucosamine/Chondriton

Glucosamine/Chondriton can be used with someone that has a shellfish allergy,True or False? - ANSWERFalse, Glucosamine/Chondriton should be used with caution with people that have a shellfish allergy What medication can be used to reduce the size of the prostate? -ANSWERFinasteride

What is the dose of Terbinafine to give to Onchymycosis on one fingernail? -ANSWER250 mg daily for 6-12 weeks for fingernail

What is the dose of Terbinafine to give to Onchymycosis on one toenail? -ANSWER250 mg daily for 3-6 months for toenail

What is the MOA of Denosumab? - ANSWERinhibits binding of RANKL to RANK,decrease osteoclast maturation and formation, decrease bone resorption.

How do Bisphosphonates work? - ANSWERInhibit osteoclast bone resorption Gallium Nitrate MOA - ANSWERinhibits bone resorption What's the ending that all Bisphosphonates have? - ANSWER- dronate Name the adverse effects of Bisphosphonates? (8) - ANSWERAtrial FibrillationAtypical Femur Fractures Esophageal Ulcers Osteonecrosis of the Jaw Ocular inflammationHyperparathyroidism Renal Impairment

What is the most common disease in menopausal women? -ANSWEROsteoporosis

What is the First-line treatment for GERD? - ANSWERDiet and Lifestylemodifications with an Antacid

If diet and lifestyle modifications with an Antacid do not help with GERD, what isthe second step in medication intervention? - ANSWERAdd H2 receptor blocker

If diet and lifestyle modifications with an Antacid, PLUS adding an H2 receptorblockers does not help with GERD, what is the third step in medication intervention? - ANSWERAdd an Proton Pump inhibitor What is an example of a H2 receptor blocker - ANSWERFamotidine CimetidineNizatidine Capsules Ranitidine

What are some examples of Proton Pump Inhibitors? - ANSWEROmeprazoleEsomeprazole Rabeprazole Pyridoxine (Vitamin B6) accelerates the systemic metabolism of levodopa therebydecreasing availability of the amino acid to the brain parenchyma, True or False? -

ANSWERTrue, Pyridoxine stimulates decarboxylase activity of Pyridoxine and candecrease the amount of levodopa available to the CNS

A patient has Parkinson's and is dealing with Tardative Dyskinesia, whatmedication would you recommend to this patient for the symptoms?

A.B. AmantadineMethyldopa C. Escitalopram

Name 3 αADHD? - ANSWERClonidine-2 Adrenergic Receptor Agonists that can be used for patients with Guanabenz Guanfacine What medication used for smoking cessation can also be used for an adult withADHD?

• ANSWERBupropion In males what do the α-1 receptors trigger? - ANSWEREjaculation How does the activation of αANSWERContraction -1 receptors affect the blood vessels? -

How does the activation of αdilation -1 receptors affect the eye? - ANSWERPupillary

How does the activation of αsphincter tone -1 receptors affect the bladder? - ANSWERIncrease

How does the activation of αRenin release -1 receptors affect the kidney? - ANSWERDecrease

Where are α-2 receptors located? - ANSWERPresynaptic Neurons

How do βHeart Rate-1 receptors affect the heart when activated? (3) - ANSWERIncrease Increase conduction at AV node Increase strength of contraction How do β-1 receptors affect the kidney? - ANSWERIncrease Renin Release How does βof the Uterus-2 activation affect the body? - ANSWERBronchial dilation Relaxation VasodilationBuild and Burn Glucose Glycogenolysis Gluconeogenesis Increase Insulin

How does activation of the M1 Muscarinic receptors affect the body? -ANSWERSalivary Glands GI Secretions CNS How does the M2 receptor affect the heart? - ANSWERDecreases HR DecreasesConduction

How do the M3 Muscarinic receptors affect the body when activated? (6) -ANSWEREye Constriction and Accomodation Lungs: bronchiolar contraction and secretion Promotes digestion increase motility and relax sphincters Increase Salivation Promotes voidingIncreases sweating and lactation.

How does Atropine affect people with asthma? - ANSWERAtropine can worsenasthma. The drying of the secretions making it harder to breathe How can Atropine be beneficial to use for an eye exam? - ANSWERAtropinedilated pupils in preparation for an eye exam

What medication can be used to combat Cholinergic effects? - ANSWERAtropine What are side effects of Atropine? - ANSWERdry mouth, decreased perspiration,blurred vision, tachycardia, constipation, and urinary retention

For patient self-identified as African American with NYHA class III-IV HFrEF whoare receiving OPTIMAL medical therapy the combination of which two medications is recommended? - ANSWERHydralazine + Isosorbide Dinitrate All patients with hypertension benefit from diuretic therapy but the patients thatbenefit the most are?

A.B. Diabetes patientsAfrican Americans C.D. Patients with Orthostatic HypotensionThose with stable angina - ANSWERB. African Americans, controlled trials have shown that diuretics can decrease the morbidity and mortality of AfricanAmericans

Aloha agonist drugs should not be given to: - ANSWERPatients with severecardiovascular conditions such as Hypertension and Cardiac Arrhythmias because alpha agonist can cause significant vasoconstriction and increase blood pressure,which can exacerbate these conditions

What is the MOA of Latanoprost? - ANSWERIncreases aqueous humor outflow byrelaxing the ciliary muscle

What are side effects of Latanoprost? (6) - ANSWERBrown pigmentation ofiris/lids/lashes Blurred Vision Burning/Stinging Conjunctival HyperemiaMacular and Conjunctival Edema Punctate Keratopathy

What is the MOA Terazosin? - ANSWERAlpha 1 antagonist Block alpha 1 receptors in the bladder neck, prostate capsule, and prostaticurethra, causing smooth muscle relaxation and decreased urethral resistance

What is the MOA of Metformin? - ANSWERIt inhibits glucose production by theliver and decreases insulin resistance.

What are adverse effects of Metformin? - ANSWERGI Disturbances Lactic Acidosis Metformin is an oral medication that reduces blood sugar and increases insulinproduction, True or False? - ANSWERFalse, Metformin primarily reduces hepatic glucose production and improves insulin sensitivity, but does not directly increaseinsulin production

What is the MOA of Sulfonylureas? - ANSWERStimulate insulin release frompancreatic beta cells.

Sulfonylureas can cause extreme Hypoglycemia when taken, but also helppatients lose weight, True or False? - ANSWERFalse, a major side effect of