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NURS | 5334 |Exam | 2 |questions |with |correct |
answers
What |are |the |neurotransmitters |of |the |PNS |- |CORRECT |ANSWER-Acetylcholine |(mediates |cholinergic | receptors) Norepinephrine/epinephrine |(mediate |adrenergic |receptors) Cholinergic |receptor |subtypes |- |CORRECT |ANSWER-nicotinic |and |muscarinic Adrenergic |receptor |subtypes |- |CORRECT |ANSWER-alpha |1, |alpha |2, |beta |1, |beta | 2 Alpha | 1 |receptor |functions |- |CORRECT |ANSWER-vasoconstriction ejaculation contraction |of |bladder |neck |& |prostate Alpha | 2 |receptor |function |- |CORRECT |ANSWER-little |clinical |significance Beta | 1 |receptor |functions |- |CORRECT |ANSWER-Heart |(increase |rate |and |force |of |contraction) Kidney |(renin |release) Conduction |of |the |AV |node Beta | 2 |receptor |functions |- |CORRECT |ANSWER-Bronchial |dilation relaxation |of |uterine |muscle vasodilation glycogenolysis Dopamine |function |- |CORRECT |ANSWER-dilates |renal |blood |vessels
Without |subtypes |- |CORRECT |ANSWER-a |drug |that |acts |on |one |site |will |alter |all |sites Cholinergic |drugs |function |to |- |CORRECT |ANSWER-Turn |on |PNS Muscarinic |Agonists |function |- |CORRECT |ANSWER-mimic |the |effects |of |acetylcholine |at |muscarinic | receptors Bethanechol |function |- |CORRECT |ANSWER-constricts |bronchi, |increase |GI |tone |and |motility, | contraction |of |detrusor |muscle |and |relaxes |trigone |and |sphincter Bethanechol |used |for |- |CORRECT |ANSWER-urinary |retention bethanechol |adverse |effects |- |CORRECT |ANSWER-hypotension, |abd |cramps/diarrhea, |increased | salivation, |asthma |exacerbation Cevimeline |- |CORRECT |ANSWER-treats |dry |mouth |in |Sjogren |Syndrome Pilocarpine |- |CORRECT |ANSWER-topical |therapy |for |glaucoma Acetylcholine |- |CORRECT |ANSWER-Used |for |mitosis |(pupil |constriction) |after |cataract |surgery Muscarinic |poisoning |treated |with |- |CORRECT |ANSWER-atropine Drugs |that |turn |off |PNS |- |CORRECT |ANSWER-Muscarinic |antagonists |(parasympatholytic |drugs, | antimuscarinic |drugs, |muscarinic |blockers, |anticholinergic |drugs) Muscarinic |antagonists |function |- |CORRECT |ANSWER-selectively |block |the |effects |acetylcholine |at | muscarinic |receptors
Darifenacin Solifenacin Tolterodine Fesorterodine Trospium Oxybutynin |(Ditropan) |- |CORRECT |ANSWER-anticholinergic |side |effects Darifenacin |- |CORRECT |ANSWER-greatest |M3 |selectivity can |reduce |OAB |symptoms |while |having |no |effects |of |M1 |receptors |in |brain |or |M2 |receptors |in |the | heart Darifenacin |can |cause |- |CORRECT |ANSWER-dry |mouth |and |constipation Solifenacin |- |CORRECT |ANSWER-similar |to |darifenacin |but |can |cause |prolonged |QT |at |high |doses Tolterodine |- |CORRECT |ANSWER-nonselevtive fewer |anticholinergic |effects prolongs |QT Fesoterodine |& |Trospium |- |CORRECT |ANSWER-nonselective Scopolamine |- |CORRECT |ANSWER-Muscarinic |Antagonist used |for |motion |sickness Ipratropium |bromide |- |CORRECT |ANSWER-used |to |treat |asthma, |COPD |and |rhinits Antisecretory |Anticholinergics |- |CORRECT |ANSWER-Glycopyrrolate |(excessive |salivation) mepenzolate
methscopolamine propanthelne dicylomine |(IBS) Cholinesterase |inhibitors |- |CORRECT |ANSWER-Reversible: |Neostigmine |(manage |myasthenia |graves |by | strengthening |muscles), |Physostigmine |(treats |muscarine |antagonist |poisoning) Nonreversible |: |highly |toxic |(use |in |insecticides) Adrenergic |agonists |function |- |CORRECT |ANSWER-turn |on |Sympathetic |NS Alpha | 1 |receptor |activation |- |CORRECT |ANSWER-vasoconstriction mydriasis Alpha | 2 |receptor |activation |- |CORRECT |ANSWER-control |norepinephrine |please, |reduces |sypatheric | outflow |to |the |heart, |relieves |pain Beta | 1 |receptor |activation |- |CORRECT |ANSWER-Inotropic |effects used |for |shock enhance |AV |node |conduction Beta | 2 |receptor |activation |- |CORRECT |ANSWER-bronchodilations uterine |relaxation Epinephrine |receptor |specificity |- |CORRECT |ANSWER-alpha | 1 |and |2, |beta | 1 |and | 2 Norepinephrine |receptor |specificity |- |CORRECT |ANSWER-alpha |1, |alpha |2, |beta | 1 (used |in |cardiac |arrest |and |hypotensive |states)
pheochromocytoma adverse |effects |of |alpha | 1 |blockade |- |CORRECT |ANSWER-orthostatic |hypotension, | reflex |tachycardia, | nasal |congestion, | inhibition |of |ejaculation Na |retention Adverse |effects |of |alpha | 2 |blockade |- |CORRECT |ANSWER-reflex |tachycardia therapeutic |applications |of |beta |blockade |(mostly |beta |1) |- |CORRECT |ANSWER-Angina HTN cardiac |arrhythmias MI |- |reduce |pain, |infarct |size, |mortality Heart |Failure noncardioselective |beta |blockers |- |CORRECT |ANSWER-propanolol nadolol carvedilol labetolol cardioselective |beta |blockers |- |CORRECT |ANSWER-A- |acebutolool B- |Bisoprolo E- |Esmolol A- |Atenolol M- |metoprolol (used |for |hyperthyroid, |migraine |prophylaxis, |pheochromocytoma, |glaucoma)
Adverse |effects |of |beta | 1 |- |CORRECT |ANSWER-bradycardia decrease |CO precipitation |of |HF AV |block rebound |cardiac |excitiation adverse |effects |of |beta | 2 |blockade |- |CORRECT |ANSWER-bronchoconstriction, |hypoglycemia wean |off |beta |blockers |to |prevent |- |CORRECT |ANSWER-rebound |excitiation indirect |acting |antiadrenergic |agents |- |CORRECT |ANSWER-Clonidine Guanabenz |andguanfacine methyldope methyldopate (preferred |in |pregnancy) Clonidine |used |for |- |CORRECT |ANSWER-HTN Pain |ADHD possible |smoking |cessation, |tourettes, |opioid |withdrawl Guanabenz |andguanfacine |used |for |- |CORRECT |ANSWER-HTN, |ADHD CNS |drugs |are |limited |to |- |CORRECT |ANSWER-lipid |soluble |drugs protein |bound |or |highly |ionized |drugs |cannot |pass |blood |brain |barrier
MAOB |- |CORRECT |ANSWER-selegiline |& |rasagiline used |to |selectively |inhibit |MAO-B |in |the |CNS care |should |be |taken |to |prevent |serotonin |syndrome |by |administering |concurrently |with |TCAs/Is |etc. Can |be |used |first |line |for |mild |parkinson Amantadine |- |CORRECT |ANSWER-help |with |dyskinesias |in |later |stages |of |PD Off |times |in |PD |can |be |helped |by |- |CORRECT |ANSWER-dopamine |agonsists COMT |inhibitors MAO-B |inhibitors Depression |in |PD |treated |with |- |CORRECT |ANSWER-Amitriptlyne SSRI |will |cause |psychosis Alzheimers |- |CORRECT |ANSWER-ACH |levels |90% |below |normal Drugs |in |alzheimers |- |CORRECT |ANSWER-slow |loss |of |memory |and |cognition |and |prolong |independent |function Cholinesterase |inhibitors |(drugs |for |Alzheimers) |- |CORRECT |ANSWER-Donepezil galantamine rivastigmine memantine (only | 4 |drugs |approved |for |alzheimers |treatment)
Drugs |for |muscle |spasms |- |CORRECT |ANSWER-Diazepam Cyclobenzaprine Tizanidine Metaxalone |(least |sedating) Chlorzoxazone (all |carry |risk |for |dependence) seizure |drugs |- |CORRECT |ANSWER-Phenytoin | Fosphenytoin carbamazepine valproic |acid ethosuximate phenobartial primidone oxcarbazepine lamotrigine gabapentin pregabalicn |lyrica levetiracetam topiramate tigabine zonisamide felbamate lacosamide rufinamide vigabatrin ezogabine
gabapentin |- |CORRECT |ANSWER-dizziness |and |drowsiness dose |4-5 |times |daily neuropathic |pain, |migraine, |fibromyalgia, |hot |flashes pregabalin |lyric |- |CORRECT |ANSWER-controlled |level |V expensive decreases |dizziness |and |fog |oaf |gabapentin diabetic |neuropathy topiramate |- |CORRECT |ANSWER-seizures bipolar migraine neuropathic |pain binge |eating alcohol |and |cocaine |dependence first |generation |antipsychotics |- |CORRECT |ANSWER-extrapyramidal |symptoms second |generation |antipsychotics |- |CORRECT |ANSWER-weight |gain Haloperidol |- |CORRECT |ANSWER-1st |gen |antipsychotic Given |PO |or |IM Fluphenazine low |potency Chlorpromazine |(Thorazine) |- |CORRECT |ANSWER-1st |gen |antipsychotic
Clozapine |- |CORRECT |ANSWER-2nd |gen |antipsychotic oldest |drug |w |most |side |effects BBW: |agranulocytosis DM | Dyslipidemia Weight |Gain Risperidone |- |CORRECT |ANSWER-2nd |generation |antipsychotic Schizophrenia |& |Bipolar extrapyramidal |SE |at |high |doses Paliperidone |- |CORRECT |ANSWER-2nd |gen |antipsychotic Schizoaffective |disorder long |acting |injectable |available metabolized |by |kidney Olanzapine |(Zyprexa) |- |CORRECT |ANSWER-2nd |gen |antipsychotic sedation weight |gain DM Ziprasidone |(Geodon) |- |CORRECT |ANSWER-2nd |gen |antipsychotic causes |prolonged |QT Quetiapine |(Seroquel) |- |CORRECT |ANSWER-2nd |gen |antipsychotic
effects |don't |start |for |week cause |weight |gain, |bleeding,bruxism side |effects |of |SSRI |- |CORRECT |ANSWER-vivid |dreams ED N/V hyponatremia SNRI |- |CORRECT |ANSWER-Selective |Norepinephrine |Reuptake |Inhibitor Venlafaxine Desvenlafaxine |(pritisq) Duloxetine |(Cymbalta) Levomincaipran |(Fetzima) same |use |and |SE |of |SSRI Buproprion |(Wellbutrin, |Zyban) |- |CORRECT |ANSWER-acts |as |a |stimulant suppresses |appetite helps |with |sexual |SE |of |SSRI can |cause: dry |mouth constipation seizures St. |John |Wort |- |CORRECT |ANSWER-DONE |GIVE |WITH |SSRI TCAs |- |CORRECT |ANSWER-drowsiness
anticholinergic beers |list caution |in |heart |pts MAOI |- |CORRECT |ANSWER-tyramine |toxicity rarely |prescribed Mirtazapine |- |CORRECT |ANSWER-weight |gian causes |drowsiness trazadone |- |CORRECT |ANSWER-lots |of |drowsiness Lithium |uses |- |CORRECT |ANSWER-mood |stabilizer requires |a |lot |of |monitoring Bipolar alcoholism bullemia schizo glucocorticoid |induced |psychosis Side |effects |of |lithium |at |therapeutic |level |- |CORRECT |ANSWER-GI temors drowsiness polyuria renal |toxicity goiter hypothyroid teratogenesis
SE |is |weight |gain benzodiazepines |used |for |- |CORRECT |ANSWER-anxiety insomnia seizure |disorders muscle |spasm ETOH |withdrawal periop if |using |for |sleep- |diazepam |is |long |acting anxiety |use |short |acting- |lorazepam |and |alprazolam SE |of |benzos |- |CORRECT |ANSWER-tolerance/dependence CNS |depression anterograde |amnesia sleep |while |driving respiratory |depression Barbiturates |have |_____ |subclasses |- |CORRECT |ANSWER- subclasses |of |barbiturates |- |CORRECT |ANSWER-ultrashort |acting |(thiopental) short |to |intermediate |acting |(seobarbital) long |acting |(phenobarbital) SE |of |barbiturates |- |CORRECT |ANSWER-tolerance physical |dependence Uses |of |barbiturates |- |CORRECT |ANSWER-seizure |disorders induction |of |anesthesia
insomnia 6 |benzodiazepines |approved |for |anxiety |- |CORRECT |ANSWER-alprazolam lorazepam diazepam chlordiazepoxide clorazepate oxazepan buspirone |used |to |treat |- |CORRECT |ANSWER-anxiety |w |no |abuse |potential, |slow |acting SSRIs |- |CORRECT |ANSWER-escitalopram citalopram fluxetine fluvoxamine paroxetine sertraline SNRI |- |CORRECT |ANSWER-venlafaxine duloxetine |(cymbalta) ADHD |treatment |- |CORRECT |ANSWER-stimulatants- |release |norepi |and |dopamine |by |inhibiting | reuptake nonstimulants TCAs Atomexetine |(Straterra) Bupropion types |of |stimulants |for |ADHD |- |CORRECT |ANSWER-methylphendiate
