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Nephrology and Gastroenterology Exam Prep: Key Concepts and Review Questions, Exams of Nursing

A comprehensive review of key concepts related to nephrology, focusing on conditions such as nephrotic syndrome, acute kidney injury (aki), and chronic kidney disease (ckd). It covers essential aspects of cirrhosis and pancreatitis, including their causes, symptoms, and treatments. The material is presented in a question-and-answer format, making it ideal for exam preparation and quick review. It also addresses critical nursing care considerations, such as monitoring during dialysis and managing complications. This study guide is designed to help students and healthcare professionals reinforce their understanding of renal and gastrointestinal disorders, ensuring they are well-prepared for exams and clinical practice. It includes key points on assessment, diagnosis, and management strategies, making it a valuable resource for medical education and professional development.

Typology: Exams

2024/2025

Available from 06/05/2025

vivian-mungai
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NUR 265 EXAM 1/2025-2026/GRADED A+
What is nephrotic syndrome?
A condition of increased glomerular permeability that allows larger molecules
to pass through the membrane into the urine and then be excreted.
What are key features of nephrotic syndrome?
-Massive proteinuria
-Hypoalbuminemia
-Edema (facial and periorbital)
-Lipiduria
-Hyperlipidemia
-Increased coagulation
-Reduced kidney function
In nephrotic syndrome, severe protein loss in the urine is greater than what?
3.5g in 24 hours
What is nephrotic syndrome treated with?
-immunosuppressant agents (if immunity based).
-ACE inhibitors (decreased protein loss in urine)
-statins (improve blood lipid levels).
-Heparin (used to treat vascular effects and improve kidney function)
Describe the "risk" stage for AKI
creatinine x 1.5 of normal, and GFR reduced by 25%
Describe the "injury" stage for AKI
creatinine x2 & GFR reduced by 50%
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NUR 265 EXAM 1/2025-2026/GRADED A+

What is nephrotic syndrome? A condition of increased glomerular permeability that allows larger molecules to pass through the membrane into the urine and then be excreted. What are key features of nephrotic syndrome?

  • Massive proteinuria
  • Hypoalbuminemia
  • Edema (facial and periorbital)
  • Lipiduria
  • Hyperlipidemia
  • Increased coagulation
  • Reduced kidney function In nephrotic syndrome, severe protein loss in the urine is greater than what? 3.5g in 24 hours What is nephrotic syndrome treated with?
  • immunosuppressant agents (if immunity based).
  • ACE inhibitors (decreased protein loss in urine)
  • statins (improve blood lipid levels).
  • Heparin (used to treat vascular effects and improve kidney function) Describe the "risk" stage for AKI creatinine x 1.5 of normal, and GFR reduced by 25% Describe the "injury" stage for AKI creatinine x2 & GFR reduced by 50%

Describe the "failure" stage for AKI creatinine x3 normal, & GFR reduced by 75% (Cant fix) Describe Prerenal AKI. Give examples. Decreased perfusion to kidneys.

  • NSAIDs
  • Severe dehydration
  • Renal artery stenosis
  • MI or HF resulting in low ejection fraction and low cardiac output
  • Blood/ fluid loss Describe Intrarenal AKI. Give examples. Tissue damage to the actual kidneys.
  • Glomerulonephritis or inflammation of the glomeruli
  • Sepsis
  • Intrarenal bleeding
  • Pyelonephritis Describe Postrenal AKI. Give examples. Obstruction that occurs after the kidney.
  • Enlarged prostate (BPH)
  • Bladder Cancer
  • Kidney stones How do you determine the mean arterial pressure (MAP)? Systolic + (Diastolic*2) / What is the MAP needed to perfuse the kidneys? 65 mmHg

•Muscle cramps •Uremic frost on skin •Itching •Fatigue and lethargy •Hiccups •Edema •Dyspnea •Paresthesia's What effects can CKD have on the cardiac system

  • HTN
  • Heart failure (major problem. Call the doctor)
  • Pericarditis What effects can CKD have on the Integumentary system
  • Uremic frost What are the dietary restrictions on CKD?
  • Protein (restrict early in disease process to preserve kidney function)
  • Potassium
  • Fluid
  • Sodium Describe hemodialysis
  • 3x a week- 4 - 5 hours
  • At risk for bleeding do to heparin
  • Extremely fatigued post.
  • Vitals and weight before and after
  • Slight fever post is normal. Monitor.

Describe peritoneal dialysis

  • Sterile procedure at home where catheter is placed into the abdomen
  • Wear a mask
  • Solution may be warmed using a heating bag or blanket, not microwave!
  • Make sure patient turns and repositions to mix solution in the cavity Describe nursing care for an AV fistula.
  • Palpate and auscultate- bruit and thrill
  • Distal pulses
  • ROM- helps form the fistula
  • Monitor for infection
  • No heavy lifting or carrying
  • No pressure
  • Aneurysm can form at AV fistula site Describe dialysis disequilibrium syndrome
  • Life threatening! (occurs if fluid is pulled off too fast)
  • S/S: restless, headache, decreased LOC, seizures, coma
  • Call a rapid immediately
  • Give barbiturates and anticonvulsants What is cirrhosis? An extensive, irreversible scarring of the liver. What are common causes of cirrhosis?
  • ETOH
  • Viral hepatitis (HEP C)
  • Autoimmune hepatitis
  • Stage 4: metabolic acidosis, unresponsiveness leading to death in most patients, unarousable What causes hepatic encephalopathy? The buildup of ammonia in the body Describe the physical assessment of an end stage cirrhosis patient.
  • Ascites
  • Jaundice
  • Coagulation problems
  • Fatigue
  • Spider angiomas
  • Petechiae
  • Liver flaps (asterixis) What is a Blake-Moore tube used for? Esophageal Varices Describe a paracentesis.
  • A procedure that is needed to get rid of the fluid in the abdomen
  • Have the pt. void before the procedure (ensures the bladder is out of the way and wont get punctured)
  • Patient is positioned in fowlers position in bed

What are the treatments for cirrhosis? Transplant is the only cure! Describe the diet for a patient with cirrhosis.

  • Small frequent meals
  • High carbs
  • High protein
  • Moderate fats
  • Moderate vitamins What medications are given to patients with cirrhosis?
  • Diuretics
  • PPI or H blockers
  • Broad spectrum antibiotics
  • FFP-coags
  • Platelets thrombocytopenia Describe acute pancreatitis. A serious and at times life threatening inflammation of the pancreas. It is caused by premature ativation of excessive pancreatic enzymes that destroy tissues and pancreatic cells (basically the pancreas starts digesting itself) What are causes of acute pancreatitis?
  • Choleylithiasis
  • Trauma to pancreas
  • Chronic ETOH consumption

Describe chronic pancreatitis. Progressive,destructive disease of the pancreas that has remissions and exacerbation. Pain is not described as "boring" pain What are the signs and symptoms of chronic pancreatitis?

  • LUQ pain (described as burning and gnawing)
  • Muscle wasting
  • Unexplained weight loss
  • 3 P's of diabetes (due to lack of insulin production)
  • Steatorrhea
  • Fatigue What needs to be taught about enzyme replacement?
  • Take enzymes with meals and snacks and follow with a glass of water
  • Administer enzymes after H2 blockers or PPI
  • Swallow without chewing to avoid irritation in the mouth
  • If can't swallow, place in gelatin casing and eat with apple sauce
  • Don't mix enzymes in protein-rich food!
  • Wipe your lips after taking enzymes
  • Don't crush enteric coated preparations
  • Follow up all labs What type of diet is a pt with chronic pancreatitis on? Bland...all the time

What is thrombocytopenia? Platelet numbers are below what is needed for blood clotting. Pt. will start bleeding spontaneously when the platelets fall below 20, Describe bleeding precautions

  • Soft toothbrush
  • Electric razor
  • Fall precautions What medication is administered in thrombocytopenia? Platelets if needed What will a patient with thrombocytopenia look like They will have petichae and ecchymosis What is Heparin induced thrombocytopenia (HIT)? Occurs as a paradocical/rebound effect of heparin, therefore the opposite action of heparin occurs (cloting). At risk for PE or DVT What med is given to treat HIT? Argatroban (anti-coag)

What needs to be done when assessing chest pain? PQRST P-provoking? at rest or activity? Q-quality. What type of pain? R-radiating? S-severity? rate from 1- 10 T-timing. How long?

  • What type of pain? sharp, dull, squeezing
  • Take a deep breath, does pain get better or worse with breathing?
  • Does pain feel better if you reposition? Describe the difference between respiratory and cardiac pain. MI: Describes pain as dull or pressure ("elephant on chest"), big breath or repositioning doesn't change the pain Resp.: Sharp intermittent pain with SOB. Changing positions helps the pain Describe MONA Morphine, Oxygen, Nitro, Aspirin Administer based on ABC's What is the pre-cath procedure?
  • labs (check for prerenal disease)
  • consents
  • 12 lead EKG
  • Shave prep
  • ALLERGIES and Medications What is a normal troponin lab value? 0 - 0. Describe post cath care.
  • Put them on tele monitor
  • Keep affected leg straight- keep clot in place
  • Keep HOB less than 30 degrees
  • Don't want to kink @ leg
  • Hematoma will burst and bleed!
  • Pulse check of affected extremity
  • IV fluids Describe contraindications for thrombolytic therapy Absolute
  • Any prior intracranial hemorrhage
  • Cerebral vascular lesion
  • Known malignant intracranial neoplasm
  • Ischemic stroke within 3 months
  • Suspected aortic dissection
  • Active bleeding
  • Closed head or facial trauma with in 3 months
  • Monitor for drainage!: If more than 150 mL/hour call rapid!!!! PVC VTACH VFIB ASYSTOLE AFIB What is the #1 complication with a CABG? Sternal infection. Use antibiotics and assess REEDA What is cardiac tamponade? It occurs when fluid quickly accumulates in the pericardium and causes a sudden decrease in cardiac output What are nursing consideration for a cardiac tamponade?
  • Check chest tubes for acute decrease in drainage
  • They will have JVD with clear lung sounds
  • Muffled heart tones
  • Hypotension Emergent and must be fixed ASAP What are the two types of surgeries to repair a broken valve? Bilogical: From pigs. Lasts 5-7 years. Body does not reject it Prosthetic: Man made, lasts up to 20+ years. Body will reject so coumadin is needed In which type of cardiomyopathy is Digoxin contraindicated? Hypertrophic Describe dilated cardiomyopathy The walls are very thin and everything is dilated Describe hypertrophic cardiomyopathy the thickening of the heart muscle How can cardiomyopathy be treated? Medically or surgically
  • Heart transplant
  • Rest
  • Medications to increase cardiac output

A bacterial infection: normally staph or strep What long term antibiotic is the patient with endocarditis on? Usually Vanco What are the S/S of abdominal aortic aneurysm (AAA)? gnawing pain in abdomen, flank, or back lasting for hours, pulsating in upper abdomen. Listen for bruit NEVER PALPATE PULSATING ABDOMEN!!!- RUPTURE If pain worsens and moves down the leg it is an emergency!!! What medication is given if the patient is in sinus bradycardia? Atropine. Give IV fluids and oxygen What is the treatment for sinus tachycardia? treat the underlying cause. Valsalva maneuver, stress management What medications are given if the pt is in atrial fibrillation? Amiodarone, diltiazem, metoprolol, digoxin

What is the normal range for H&H? Hemoglobin: M: 14-18 g/dL F: 12-16 g/dL Hematocrit: M: 42%-52% F: 37%-47% What is the normal range for BUN? 10 - 20 mg/dL What is the normal range for creatnine? M: .06-1.2 mg/dL F: 0.5-1.1 mg/dL What is the normal PT range? 11 - 12.5 sec **1.5-2.5 times the normal on Coumadin What is the normal INR range? 0.9-1.2 sec What is the normal PTT range?