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NSG 552 Psychopharmacology Exam 3
(Wilkes University) Comprehensive
Practice Questions |Questions & Verified
Answers (A+ Graded Exam)
What is the mechanism of action of Naloxone? Pure opioid antagonist that competes and displaces opioids receptor sites. What medications treat opioid disorder? Methadone; Buprenorphine, buprenorphine + Naloxone What medication for opioid use disorder is used with comorbid pain? Buprenorphine + Naloxone Inappropriate use of what substance may be due to uncontrolled pain? Opioids What are the Naltrexone delivery methods? Tablet; Injectable; Implant What is one form of Naltrexone delivery method limited to inpatient use? Implant What is the mechanism of action buprenorphine? Mu receptor partial agonist for opioid withdrawal What medication taken too soon after last opioid use increases the chances of intense withdrawal that comes on very quickly (precipitated withdrawal)? Buprenorphine What are symptoms of opioid intoxication? Nausea and vomiting; Respiratory depression;
Constipation; Itching; Mioisis (small pupil); Euphoria; and Sedation What withdrawal symptoms of opioids? Nausea and vomiting; Diarrhea; Dehydration; Irritability; Restlessness; Yawning; Twitching; Increased heart rate and blood pressure; Chills; Increased temperature; Rhinorrhea; Lacrimation; Dilated pupils What medication is given for opioid intoxication during cardiac or respiratory depression is a concern? Naloxone What are symptoms of cocaine intoxication? Dilated pupils; Headache; Tremor; Hyper-reflexia; Twitching; MI; Nausea and vomiting; Incontinence/ARF; Rhabdomyolysis What is the treatment for cocaine intoxication? Benzodiazepines; Antipsychotics; Management of medical problems that include hypertension, stroke, cardiac arrhythmias, hyperthermia, and seizures What would not be the treatment for chest pain and MI from cocaine? Beta blockers are to be avoided due to unopposed a-adrenergic stimulation.
Acute care management; Parenteral diazepam or lorazepam; Thiamine; Antipsychotics if necessary What is the mechanism of action of disulfiram? Via negative reinforcement, where drinking is avoided due to unpleasant effects. What is the mechanism of action of Acamprosate? NMDA receptor antagonist How is Acamprosate cleared? Renally What medication can be given to patients with AUD with hepatic dysfunction? Acamprosate What medication is suitable for AUD with comorbid OUD? Naltrexone What medication reduces consumption by decreasing reinforcement properties? Naltrexone What medication only deals with physical dependence, but does not address the psychological component of smoking? NRT What medications are oral stop-smoking aids? Varenicline; Bupropion; Clonidine "Very Bad Cancer" What are the "Very Bad Cancer" medications? Varenicline; Bupropion; Clonidine What medication for smoking cessation treatment should be observed for neuropsychiatric symptoms that include changes in behavior, hostility, agitation, depressed mood, and suicide-related events that include ideation, behavior, and attempted suicide? Bupropion What is the treatment for cocaine induced chest pain or myocardial infarction?
Intravenous benzodiazepines What medications can treat agitation in patients with dementia? Atypical antipsychotics What type of medications are used only for short-term and acute episodes of aggression, agitation, and psychosis in patients with dementia? Benzodiazepines What medical emergency can be caused with TCAs, anticholinergics, benzodiazepines, non- benzodiazepines, corticosteroids, H2 blockers, and opioids in elderly patients? Delirium What is Kluver-Bucy syndrome? A type of frontotemporal degeneration (FTD) that results from bilateral lesions of the medial temporal lobe and manifests with hypersexuality and hyperorality. What type of medications are appropriate for mild to moderate dementia? Donepezil; Rivastigmine; Galantamine "Damn, Grandma's Regressing" What are the "Damn, Grandma's Regressing" medications? Donepezil; Rivastigmine; Galantamine What is the mechanism of action of memantine? NMDA receptor antagonist that promotes synaptic plasticity. What medication is used for moderate to severe dementia? Memantine What TCA has the fewest anticholinergic effects? Nortriptyline What TCA is the most appropriate in the elderly? Nortriptyline What type of medications are preferred in the elderly? SSRIs
Height; Weight; Blood pressure; Heart rate; EKG What medication is second-line treatment, a non-stimulant, used in patients with history of SUD, or when family prefers a non-stimulant? Atomoxetine What types of stimulants are use when patient needs a duration of action longer than 4 hours, improves adherence, and is less likely to be abused? Intermediate or long acting What are common adverse effects of stimulants? Dizziness; Poor growth; Decreased appetite; Insomnia; Mood lability What are "Dizzy Patients Demand Immediate Monitoring" symptoms? Dizziness; Poor growth; Decreased appetite; Insomnia; Mood lability What symptom do children exhibit that requires blood pressure and heart rate monitoring? Dizziness If dizziness in children occurs at peak, what should the patient be switched to? A longer acting formula If a patient exhibits this stimulant associated symptom, they should be switched to a shorter acting formula? Insomnia Prior to starting a stimulant, the patient history, family history, and exam should be conducted with a focus on what? Cardiovascular What stimulant side effect may require discontinuation of medication?
Tics What condition is pharmacological treatment initiated as first-line therapy after careful assessment and targets co-occurring disorders? Intellectual disability What medications should not be combined with stimulants? SNRIs; Mood stabilizers; MAOIs; Antipsychotics; TCAs What medications are "Stimulants Make Me Act Tense?" SNRIs; Mood stabilizers; MAOIs; Antipsychotics; TCAs What non-stimulant ADHD medication is most appropriate in a patient with co-occurring depression? Bupropion What type of medication class is considered a "reasonable choice" in a patient with co-occurring depression and anxiety? TCA What 2 medications are approved by the FDA to treat severe behavioral issues in ASD, specifically tantrums, self-injury, and aggression? Risperidone; Ariprazole What is the on-demand treatment for premature ejaculation? Clomipramine What medication, if combined with nitrates, can cause an unsafe drop in blood pressure, headaches, flushing, and dizziness? Sildenafil What condition may be caused by physiological (medications), psychological (depression), or hormonal (abnormal levels)? Sexual dysfunction What is the most appropriate medication for a female with depression and hyperarousal?
What is the management of IDD deficits? Behavioral therapy What stimulant medication is FDA approved for children 6+ that should not be used in patients with pre-existing cardiac conditions? Methylphenidate What FDA stimulant is approved for children 3+? Dextromethylphenidate What non-stimulant is approved for children aged 6-17? Guanfacine
