Neural tube defects in the
neonatal period
Docsity.com
Prepare for your exams
Study with the several resources on Docsity
Earn points to download
Earn points by helping other students or get them with a premium plan
Guidelines and tips
Prepare for your exams
Study with the several resources on Docsity
Earn points to download
Earn points by helping other students or get them with a premium plan
Community
Ask the community
Ask the community for help and clear up your study doubts
University Rankings
Discover the best universities in your country according to Docsity users
Free resources
Our save-the-student-ebooks!
Download our free guides on studying techniques, anxiety management strategies, and thesis advice from Docsity tutors
Neural Tube Defects - Paediatrics - Lecture Slides, Slides of Pediatrics
Neural Tube Defects, Neonatal Period, Termination of Pregnancy, Spina Bifida, Tube Defects Position, Tube Defects Position, Consanguinity, Folic Acid Prevention, Maternal Bloodstream. A major difference between pediatrics and adult medicine is that children are minors and, in most jurisdictions, cannot make decisions for themselves. This is one of lecture on Pediatrics. Main points of this lecture given above.
Typology: Slides
2011/2012
1 / 13
This page cannot be seen from the preview
Don't miss anything!
Related documents
Partial preview of the text
Download Neural Tube Defects - Paediatrics - Lecture Slides and more Slides Pediatrics in PDF only on Docsity!
Neural tube defects in the
neonatal period
Incidence
Authors Data published
Defects Termination of pregnancy
Incidence/Birth
Waleed Murshid (KSA) [ 1]
2000 Spina bifida - 1.09/
Amira Masri (Jordan) [2]
2006 NTD - 1.1/
( Syria ) [3]
A.K.Njamnshi (Cameroon) [4]
2008 NTD - 1.99/
Louis duplessis (Australia )[5]
2008 NTD 79% 1.3/
Including termination of pregnancy ( 0. 26) CDC (USA)[6] (^2007) Spina bifida
- 0.17/ ( 2005)
Neural tube defects position
Spina bifida cystica
Encephalocele Anencephaly
A.K.Njamnshi
Cameroon
2008 (98cases) [4]
71% 21.1%^ 5.4%
Hamza Ali
Children hospital
Damascus 2008 ( 170 cases) [3]
155 cases 15 cases
Consanguinity
consanguinity Percentage
Waleed Murshid (KSA) [ 1] 89%
Hamza Ali
Children hospital
Damascus 2008
( 170 cases) [3]
67 cases /170 39.4%
Folic acid prevention
Periconceptional folic Acid prevention
During pregnancy Folic Acid prevention
A.K.Njamnshi
Cameroon
2008 (98cases) [4]
Hamza Ali
Children hospital
Damascus 2008 ( 170 cases) [3]
Screening
- AFP (In the amniotic fluid or maternal bloodstream )
- Detection of a neural tube defect with fetal Ultrasonography
risk factors include :
- previous pregnancies have been affected with NTDs
- some anticonvulsants such as carbamazepine and sodium valproate
- pregnancies complicated by diabetes at conception
Clinical signs
Total Paralysis
Of lower limb Percentage
Amira Masri (Jordan) [2}
Hamza Ali
Children hospital
Damascus 2008
( 170 cases) [3]
Complications
Leakage of
CSF
Proved
Meningitis
CNS
Abscess
Hamza Ali
Children hospital
Damascus 2008
( 170 cases) [3]
Recommendation
Refer patients as early as possible to special centers which
cover different areas in a given region.
- Periconceptional folate supplementation has been shown to
reduce the incidence of NTDs, with data suggesting that a daily
intake of 0.4mg of folic acid reduces the risk of 1st neural tube
defects by up to 70% and Women at high risk require 5mg
daily.
- Screening and Detection