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Neural Control of
Exercising Muscle
chapter
Learning Objectives
- (^) Learn the basic structures of the nervous system.
- (^) Follow the pathways of nerve impulses from initiation to muscle action.
- (^) Discover how neurons communicate with one another and learn the role of neurotransmitters in this communication. (continued)
ORGANIZATION OF THE NERVOUS SYSTEM
STRUCTURE OF A NEURON
Resting Membrane Potential (RMP)
- (^) Difference between the electrical charges inside and outside a cell, caused by separation of charges across a membrane.
- (^) High concentration of K+^ inside the neuron and Na+ outside the neuron.
- (^) K+^ ions can move freely, even outside the cell, to help maintain imbalance.
- (^) Sodium-potassium pump actively transports K+^ and Na+ ions to maintain imbalance.
- (^) The constant imbalance keeps the RMP at –70mV.
Sodium/potassium
pump using
energy from ATP
produces a
polarized
membrane
What Is an Action Potential?
- (^) Starts as a graded potential.
- (^) Requires depolarization greater than the threshold value of 15 mV to 20 mV.
- (^) Once threshold is met or exceeded, the all-or-none principle applies.
RESTING STATE
Events During an Action Potential
- Resting state
- Depolarization
- Propagation of an action potential
- Repolarization
- Return to the resting state with the help of the sodium- potassium pump
The Velocity of an Action Potential Myelinated fibers
- (^) Saltatory conduction—potential travels quickly from one break in myelin to the next.
- (^) Action potential is slower in unmyelinated fibers than in myelinated fibers. Diameter of the neuron
- (^) Larger-diameter neurons conduct nerve impulses faster.
- (^) Larger-diameter neurons present less resistance to current flow.
Key Points (continued) The Nerve Impulse
- (^) Impulses travel faster in myelinated axons and in neurons with larger diameters.
- (^) Saltatory conduction refers to an impulse traveling along a myelinated fiber by jumping from one node of Ranvier to the next. http://staff.washington.edu/chudler/ap.html http://www.bris.ac.uk/synaptic/public/basics_ch1_2.html http://www.tvdsb.on.ca/westmin/science/sbioac/homeo/action.htm
The Synapse
- (^) A synapse is the site of an impulse transmission between two neurons.
- (^) An impulse travels to a presynaptic axon terminal, where it causes synaptic vesicles on the terminal to release chemicals into the synaptic cleft.
- (^) Chemicals are picked up by postsynaptic receptors on an adjacent neuron.
The Neuromuscular Junction
- (^) The junction is a site where a motor neuron communicates with a muscle fiber.
- (^) Axon terminal releases neurotransmitters (such as acetylcholine or epinephrine), which travel across a synaptic cleft and bind to receptors on a muscle fiber.
- (^) This binding causes depolarization, possibly causing an action potential.
- (^) The action potential spreads across the sarcolemma, causing the muscle fiber to contract.
The Neuromuscular Junction