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NASM CNC Exam | 85 Questions with 100% Correct Answers | Updated & Verified | 2025- 2026
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What refers to the reproducibility of test results? ✔✔Precision
A process that monitors the accuracy and reproducibility of results through the use of control specimens. ✔✔Quality control
What detects any progressive drift off values to one side of the average for at least 3 days? ✔✔Trend
A means by which quality control between laboratories is maintained ✔✔Proficiency testing
OSHA has defined BLANK as blood and blood products, contaminated sharps, pathology waste products, and microbiological waste. ✔✔Infectious waste
Beginning with the moment the specimen is collected and transported to the laboratory, to the analysis itself and reporting of the results, must be documented by a process known as ✔✔Chain of Custody
Specific microscopic tests (wet mounts, potassium hydroxide (KOH) preperations, fern test) performed by a physician for his or her own patients is known as ✔✔Provider-performed microscopy (PPM)
Describes how close a test result is to the true value. ✔✔Accuracy
are used for Ordinary combustibles. ✔✔Class A Fire Extinguishers
Pathogens that are rarely seen in the United States, these agents have the highest priority, can be easy transmitted,result in high mortality rates and can have major public health impact ✔✔Category A
Moderately easy to disseminate, moderate morbidity rates and low mortality rates. Agents brucellosis, epsilon toxin, food contaminants, glanders, melioodosis, psittacosis, Q fever,and ricin toxin are classified as. ✔✔Category B
All chemical manufacturers and distributors must comply with all of the new provisions in the revised standards by june 1 blank. ✔✔ 2015
Electrical Equipment Fires ✔✔Class C Fire Extinguishers
Third-highest Priority and inclde emerging pathogens that could be negineeered for mass disseination in the future because of availability, ease of production and dissemination? ✔✔Category C
What regulation became law in 1992, requires that laboratories develop, implement and comply with a plan that ensures the protective safety of laboratory staff to potential infectious blood- borne pathogens and manage and handle medical waste in a safe and effective manner? ✔✔Occupational Exposure to Bloodborne Pathogens
Detects an increase in frequency of both high and low minimally acceptable values ✔✔Dispersion
Ordinary Combustibles ✔✔Class A Extinguishers
All employees who work with hazardous chemicals will be required to be trained about the new labels and the elements of the Safety Data Sheet (SDS) by December 1 of BLANK ✔✔ 2013
SDS Section Requirement ✔✔16 Sections
A patient with hyperparathyroidism will have which type of kidney stone? ✔✔Calcium Oxalate
A Western blot is used to detect ✔✔RNA
Which of the following are the two methods used to characterize monoclonal proteins? ✔✔IEP and IFE
In POCT testing. glucose is commonly measured and uses what type of sensor? ✔✔Biosensors
which of the following is one of the most common clinical applications of GC-MS analysis? ✔✔Drug Testing
patients can experience complications resulting from a phlebotomy procedure. The complications can be divided into six major categories, which are ✔✔VASCULAR COMPLICATIONS , INFECTIONS , ANEMIA, NEUROLOGICAL COMPLICATIONS, CARDIOVASCULAR COMPLICATIONS, AND DERMATOLOGICAL COMPLICATIONS.
What would cause the constituents, including enzymes acid phosphatase, lactate dehydrogenase (LDH) and (AST) to significantly elevate the value obtained for these substances in serum? ✔✔Hemolyzed Specimens
Three division order of precaution ✔✔Contact, Airborne, Droplet
How many errors are caused by preanalytical errors? ✔✔Two Thirds
Order of vein choice ✔✔Cephalic, Basilic, Median
Function of the stage of Microscope ✔✔Place to put object being observed
which method of analysis is the most widely used method for determination of total protein? ✔✔Kjeldahl
which tissue is considered the richest source of acid phosphatase? ✔✔Prostate
What is relatively cardiospecific because of excellent sensitivity within 4 to 6 hours after onset of symptons in myocardinal infarction? ✔✔CK-MB
What is the recommendation of the Enzyme Commission of the International Union of Biochemistry for reporting enzyme results? ✔✔IU
The enzyme is found primarily in the pancreas. ✔✔ACP
Creatinine Kinase can be seperated into three distinct molecular forms. CK-BB is mainly indicated by what tissue? ✔✔Brain
Disorders of skeletal muscle will show elevated levels of which LDH isoenzyme? ✔✔LDH-5 Is usually asociated with disorders.
Two hormones produced by the thyroid gland from the essential trace mineral iodine and responsible for the regulation of metabolic activities in all body cells are? ✔✔Thyroxine and triiodothyronine.
The endocrine gland once thought to have no role in the phsyiology of adults, but now known for its crucial role in T-cell maturation is the? ✔✔Thymus Gland
What is the function of the pituitary gland? ✔✔Master gland that stimulates the other glands to produce hormones as needed.
Lipid metabolism involves four distinct pathways. Which pathway takes newly synthesized chylomicrons and then goes to convert some cholesterol to bile acids? ✔✔Exogenous Pathway
Which class of drugs plays a role in determining the success of any transplant program? ✔✔Immunosuppressive
What is elevated in carcinomas and benign disease of various organs, including pelvic inflammatory disease (PID) and endometriosis, but is the most useful in ovarian and endometrial carcinomas? ✔✔CA 125
Combined hyperlipoproteinemia is defined by the presence of which lipid levels? ✔✔cholesterol and LDL
A significant increase in the plasma concentrations of urea and creatinine, in kidney insufficiency, is known as? ✔✔Azotemia
An inflimmation sensitive protein that can be measured by immunoassays is? ✔✔C-Reactive protein (CRP)
the drug phenobarbital is a slow-acting barbiturate that effectively controls several type of seizures and is considered which class of drug? ✔✔Anti-epileptic
A complex of three proteins that bind to the thin filaments of striated cardiac or skeletal muscle and regulate muscle contraction? ✔✔Troponin
Which type of antibiotic would you see tested only on inpatients because they are not well absorbed from the gastrointestinal tract? ✔✔Aminoglycosides
Which tissue is considered the richest source of acid phosphatase? ✔✔Prostate
Which method of analysis is the most widely used method for determination of total protein? ✔✔Biuret
Patients who are being transfused platelets need to be evaluated for the effectiveness. If a patient is unresponsive to platelet transfusions, they are considered to be? ✔✔Refractory
If I wanted to standardize an instrument to help eliminate errors, that could harm a patient or donor, what is the process? ✔✔Calibration
Which of the following is an eample of good record keeping in Blood Banking? ✔✔Recording data on appropriate log
Which medication below will cause a temporary deferral? ✔✔Proscar
What is the acid fast staining method using the fluorochromes, auramine and rhodamine, and is a rapid screening method for detection? ✔✔Myocabacterium spp
which agar is a selective and differential media for the isolation of enteric pathogens such as Salmonella and shigella spp? ✔✔Hektoen Enteric Agar
The mathematics modeling of drug concetration in circulation which helps assist in establishing a dosage regimen is? ✔✔Pharmacokinetics
Which of the drugs of abuse are a group of psychoactive compounds found in marijuana? ✔✔Cannabinoids
Which of the following is/are flourescent stain(s) used in the detection of the mycobacteria? ✔✔Auramine/rhodamine
Endogenous anaerobes are organisms ✔✔That exist inside the body of animals and can cause endogenous infections.
What is the process used to decrease the number of microorganisms that are present on the skin? ✔✔Antisepsis
resistant, kanomycin susceptible and colistin susceptible. The most likely identification is? ✔✔Fusobacterium nucleatum
Phenylethyl alcohol agar (PEA) inhibits the growth of gram negative organisms except? ✔✔Pseudomonas aeruginosa.
What gram positive cocci are most frequently associated with UTI's in young, secxually active females? ✔✔Staphylococcus Saprophyticus
A gram negative rod > 100,000 col/cc is recovered from a midstream urine. The isolate is swarming over the blood plate, produces hydrogen sulfide on TSIA, and hydrolyzes urea, indole negative and ornithine positive. What is the likely organism identification? ✔✔Proteus mirabilis
An optochin disk (P disk) may be used to help identify what organism? ✔✔Streptococcus pnuemoniae
Xylose-Lysin-Desoxycholate agar is a selective and differential agar for the recovery of? ✔✔Salmonella and Shigella
Which agar is both a selective and differential medium for gram negative bacilli and can be used in the primary plating of routine cultures? ✔✔Eosin-methylene blue agar
The most common causes of bacterial conjunctivitis in children are? ✔✔Haemophilus influenzae, Streptococcus pheumoniae and occasionally Staphylococcus aureus.
Stool specimens received for culture should be routinely examined for what pathogens in the United States? ✔✔Campylobacter, Salmonella and Shigella spp
What member of the normal ora flora in humans is often associated with trauma,especially after human bites or "clenched fist wounds" or after the skin has been broken by human teeth and occurs in mixed infections? ✔✔Eikenella Corrodens
What are those infections acquired in the hospital or health ✔✔Nosocomial Infection
Which of the following is a definition of a recall in blood banking? ✔✔Manufacturers removal of products from the market that may compromise the safety of the recipient.
Fresh Frozen Plasma (FFP) contains coagulation factors to include the labile factors V and VIII. What does the term labile mean? ✔✔Does not store well at temperatures above -18 C
Whole blood units are stored at 1 - 6 C for how many days if colected in CPDA-1? ✔✔35 Days
If a blood pressure cuff is used for blood donor venipuncture, what should the cuff be inflated to? ✔✔60 to 80 mmHg
The most common cause of community-acquired urinary tract infections is? ✔✔Escherichia coli
What is essentialy sheep blood agar with phenylethyl alcohol added? ✔✔Phenylethyl alcohol agar
A nosocomial infection occurs when the? ✔✔Patient acquires the infection while in the hospital or health care facility
What is defined as glucose intolerance that is first recognized during pregnancy and after childbirth?
Studies have shown that a significant number of patients with this class of diabetes will develop type 2 diabetes decades after delivery. ✔✔Gestational diabetes mellitus (GDM)
Every function in the living cell depends on proteins. Most of the plasma proteins are synthesized in what organ? ✔✔Liver
Whole blood or RBCs that are packaged for shipment must be maintained at what temperature? ✔✔1 - 10 C
On blood films prepared with Wright's stain, abnormally early release of the RBC's from the marrow into the peripheral blood is indicated by the presence of nucleated RBC's or polychjromatophilic macrocytes, also known as? ✔✔Shift Cells
To perform the manual platelet count, whole blood is diluted wit hwhat solution using the unopette system? ✔✔1 % ammonium oxalate solution
Which development stage of the megakaryocyte is 25-50 um in diameter and has abundant acidophilic cytoplasm and a large multi-lobed nucleus? ✔✔Granular megakaryocyte
When Performing the Westergren method, fresh anticoagulated blood collected in sodium citrate is the preferred anticoagulant. What is the ration of blood to sodium citrate? ✔✔4 vol of blood to 1 volume of sodium citrate
The inclusion of Auer rods in blast cells and promyelocytes can help establish diagnosis of which leukemia? ✔✔Acute myeolyocytic Leukemia
Which cytochemical stain is the most sensitive and specific stain for granulocytes? ✔✔Myeoperoxidase
Which Stage of neutrophil has a nucleus with fine chromatin nucleoli and agranular cytoplasm? ✔✔Myeloblast
As the neutrophil matures, the characteristics that help distinguish the cell also change. Which neutrophil has reddish purple primary granules, also called nonspecific or azurphilic granuse? ✔✔Promyelocyte
A differential shows extreme leukocytosis, normal RBC morphology with possible NRBC's, and exhibits a shift to the left with all stages of granulocyte maturation. Which disorder is this? ✔✔Chronic myelogenic leukemia
To ensure accuracyof the hemoglobin and hematocrit the rule of three is used: hemoglobin x 3 = hematocrit/ This rule works only with these types of erythrocytes? ✔✔Normocytic, normochromic
The ESR is a measurement of the rate at which the erythrocytes settle from the plasma. In which phase of the sedimentation proccess is roulex formed? ✔✔Aggregation phase
Platelets are produced in the bone marrow by cells which are large and multinucleated called? ✔✔Megakaryocytes
Neutrophils normally mature in the bone marrow in the following stages, from the youngest to the most mature: ✔✔Myeloblast , Promyelocyte , Myelocyte , Metamyelocyte, Band and Segmented Neutrophils.
Cells gradually progress from one stage to another. In terms of cell size and cytoplasm, there is a progressive decrease in size and also a decrease in the in the intensity of the blue color because the loss of? ✔✔RNA
Which cells differentiate and acquire antigen specificity principally in thymus and in some cases in other lymphoid organs? ✔✔T Lymphocytes
The mononuclear phagocytes that are important in the defense against microorganisms, including mycobacteria, fungi, bacteria, protozoa, and viruses are? ✔✔Monocytes and macrophages
iron defeciency anemia ✔✔Decreased Iron intake, increased iron loss, an error of iron metabolism, and/or increased iron requirements in infancy, pregnancy and lactation.
What is milky white in color and may interfere with chemical determinations such as triglyceride assay? ✔✔Lipemic Specimens
What uses glass ion-exchange membrane for sodium assay and a valinomycin neutral-carrier membrane for potassium assay and has been incorporated into many automated chemistry analyzers? ✔✔Ion Selective electrode (ISE) potentiometry
Which of the following may be said to be true of fluorescent spectroscopy? ✔✔High Sensitivity High Specificity
There are 5 stages to kidny disease, glomerular filtrate rate of 13 ml/min per 1.73 m 2, Which Stage is this? ✔✔Kidney Failure
The reduction of oxaloacetate to malate by malate dehydrogenase is used in the measurement of which enzyme? ✔✔AST
The immediate precursor of bilirubin is? ✔✔Biliverdin
An isolate from a properly collected abscess yields an anaerobic, gram-negative bacilli with tapered ends. The colonies were breadcrumb-like, indole positive, nitrate negative, vancomycin resistant, kanomycin susceptible and colistin susceptible. The most likely identification is? ✔✔Fusobacterium nucleatum
Phenylethyl alcohol agar (PEA) inhibits the growth of gram negative organisms except? ✔✔Pseudo,pmas aeruginosa
What type of media permit one bacterial pathogen to grow by using specific nutrients for the growth of that pathogen? ✔✔Legionella pneumophillia
Normally sterile body fluids, bone and bone marrow and solid tissues should be examined for which of the following pathogens? ✔✔Staphylococcus Aureus, Bacteroides spp , Enterobacteriaceae
What gram negative rod is associated with lobar pneumonia in hospitalized patients? ✔✔Klebsiella pneumoniae
What is the acid fast staining method using the fluorochromes, auramine and rhodamine, and is a rapid screening method for detection? ✔✔mycobacterium spp
A nosocomal infection occurs when? ✔✔Patient acquires the infection while in the hospital or health care facility
Which of the following specimens would be unaceptable for anaerobic culture? ✔✔Gingival swab
Which cardiac marker is used to evaluate heart failure and prognosis? ✔✔BNP
What hormone is hydrophobic and insoluble in water? ✔✔Steroid Hormones
A complex of three proteins that bind to the thin filaments of striated cardiac or skeletal and rugulate muscle contractions ✔✔Troponin
What is the order of draw of multiple evacuated tubes? ✔✔Blood culture (aeorobic) , Blood culture (anaerobic), blue, red, green, stopper , lavender and gray
Blood collected directly after a meal is described as a? ✔✔Postprandial specimen
Failure to apply sufficient pressure to the venipuncture site could result in ✔✔A hemotoma
What is the most accurate answer for enzyme activity on a diluted 1:4 specimen with a 500 u value? ✔✔Enzymatic Law
The Pancreas contains islets of Langerhans, which produce? ✔✔Insulin and glycogen
What is the fourth most abundant cation in the body and second most abundant intracellular ion? In addition, this electrolyte has high concentrations found in bone and muscle. ✔✔Magnesium
What is the Chief component of the nonprotein nitrogen material in the blood? It is distributed throughout the body water, and it is equal in concentration in intracellular and extracellular fluid. ✔✔Urea/Urea Nitrogen
Many cardiac conditions are treated with drugs, but only a few require TDM. The Two classes of drugs that need monitoring are the cardiac glycosides and the anti arrhythmics. Which drug belongs to glycosides? ✔✔Digoxin
The National Cholesterol Education Program (NECP) identified the following range for a borderline trigliceride result. ✔✔150-200 mg/dL
What is stimulated by the hormones glucagon, cortisol and throxine. ✔✔Gluconeogenesis
An increased ALP level in an adult would most likely be caused by? ✔✔Liver Disease
What is defined as a chemical substance produced by a specialized gland in one part of the body and carried to a distant target organ where a regulatory response is elicited? ✔✔Hormone
What additional information is typically required in order to measure enzymatic activity in a 24- hour urine test? ✔✔Weight, Height, and total volume of 24-hour collection
Electrodes and a current is passed through in order. to seperate the proteins into bands. Which band travels the farthest to the anode? ✔✔Albumin
Plasma that has been expressed into another empty attached bag that is processed as FFP, must be frozen within 8 hours of collection and stored at or below -18 C for how long? ✔✔1 Year
Which blood product would be best for a patient that the physician is concerned about that has graft versus host disease (GVHD) ✔✔Irradiated red blood cells
Fresh frozen plasma (FFP) contains coagulation factors to include the labile factors V and VIII. What does the term labile mean? ✔✔Does not store well at temperatures above -18 C
Which blood product is the cold insoluble precipitate that forms when a unit of FFP is thawed between 1 and 6 C? ✔✔Cryoprecipitate
A therapeutic phlebotomy is performed on a patient to withdraw blood from a patient for medical reasons. Which of the following is a common indication of therapeutic phlebotomy? ✔✔Polycythemia , Hemochromatosis, Porphyrias
Common Pili function is? ✔✔They help bacteria attach to the host's cell surfaces.
What cells do not have a nucleus or any membrane bound organelles such as mitochondria, and their ribosomes are a smaller size than eukaryotic ribosomes? ✔✔Prokaryotes
Certain bacteria,parasitic cysts and rare fungal forms contain mycolic acid in their cell wall and retain the basic dye despite acid alcohol rinsing and are known as? ✔✔acid-fast positive organisms
Flagella are located on blank ✔✔One end of the bacterial cell, both ends of the bacterial cell, the entire cell surface.