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NAPSRX EXAM QUESTIONS & ANSWERS 2025
NAPSRX EXAM QUESTIONS & ANSWERS 2025 Pharmaccuticals are arguably the most socially important healthcare product — ANS-v vi Pharmaceutical deveoplment is a big—risk undertaking, in which many promising leads prave disappointing — ANS-v vitae Pharmaccutical sales are highest in which gcographical regions — ANS-WWThe The U.S. accounts for about of the world's pharmaccutical revenues — ANS— vv 5% Which off the following has fueled recent growth in the pharmaccutical industry — ANS-¥W population growth and increased life expectancies According to your manual, which statement accurately describes the predicted rclationship between pharmaccutical companics and genomic rescarch facilities — ANS-W¥ partnerships between pharmaceuiteal companies and genomic prescription drug therapy is not cost—cffective for insurance companics and healthcare providers — ANS-v Vv false the high price of healthcare is explained by the high price of medicines — ANS-¢¥ v fase once of the oldest and Icast cfffective pharmaccutical marjeting techniques is DTC (direct—to—consumer) advertising — ANS-VVFaIBe what influences the number of districts in a region — ANS- vv figiregions whal is an example of the regionalization off healthcare delivery systems — ANS— vv California and Florida have differnet perscription reimbursment policies the heart of pharmaccutical sales is the regional manager — ANS-vv [alge most DMs did not start as representatives — ANS-v Vv falge how many territories arc in a typical district — ANS-vv Biome what is the most effective method for grabbing markct share — ANS-VvW pharmaceutical reps mainly visil pharmacies — ANS- vv fig it usually only takes 1—2 calls to a physician before he or she commits to prescribing your product — ANS-vv fale the pharmacist may dispense a product other than what the physician prescribed — ANS-vv fae In its broadest definition, a drug is any substance that produces a physical or psychological change in the body — ANS-v vie how docs the federal food, drug and cosmetic act (FFDCA) define a drug — ANS— vv any substance intended for usc in the diagnosis, cure, mitigation, treatment or which statement about vitamins is correct — ANS- VW MOSUOMEDOIDOdy Siteduired ADME testing measures the rate at which the body absorbs the drug, distributes it to the organs necessary to producc the desired cffect, metabolizes it into waste material and then excretes it from the body. — ANS-v vitae ADME testing is primarily used in what ficld - ANS- vv BRMEaCORMMOLIeS which statement about placcbos is correct — ANS- VW BigeeDOle Heels eamleadnto on avcrage, only about 5 off 4,000 drugs studicd in the labratory are eventually studied in peaple — ANS-vv ele which statement is truc about drugs taken sublingually — ANS- vv Sablimgual what are 3 off the 7 rights of drug administration - ANS—-V v fRGMI@nEDauOnD) pro—drugs are administered in an active form, which is metabolized into an inactive form — ANS—vv [ilipe the kidney of an 85-year-old persion exeretes drugs only as cfficicntly as that of a 35-ycar—old person — ANS-V v BEOUnGIDOo the normal age-related decrease in kidney function ccm help doctars determine an appropiate dosage based soley on a person's age — ANS-v viele what differentiates a caplet from a tablet — ANS~ Vv caplets are shaped like what will you find the legend “Caution: federal law prohibits dispensing wihtout a prescription — ANS— wv SRiDROHADOMO all) pEOSenpllOnaruns what happens to slow acetylalors — ANS-WW#Drugs that are metabolized by N— About ___ of the people in the U.S. are "slow acctylators" — ANS- vv BOM which of the following statements about drug—drug interactions is incorrect — ARS- vv drug-drug interactions are always harmful Like foods and houschold preducts, gencric drugs are usually lower quality than the brand name drugs for which they are marketed as cquivalents. - ANS-WVW Legally, biocquivalence of different versions of a drug can vary by up to — ANS-vvB0% which of the following statements about biologics is incorrect — ANS-v v fieyido “large molecules" products are developed and manuffactured by a chemical process — ANS-vv false what are drugs that attract or bind to cell receptors in order to mimic or enhance activitics by endogenous chemical messengers — ANS-V/ BBOMISES Which term denates how an API works in the body? — ANS- vv figehanistinol What cements the active and inert components together to maintain cohesive portions? — ANS- Vv Singers what docs the medical abbreviation "BID" denote — ANS-v / EMiBenanday what is Lhe medical abbreviation for "as needed” — ANS-vv BRN what components might causc paticnts' different reactions to brand name and generic drugs — ANS- v 7 Gif@PSneestiiiaitaetivennareuienes all cells have a nucleus — ANS-v vials which of the following docs not affect drig response — ANS-v v igipatignes! drug reactions are predictable becasue they do not occur after a person has been previously exposed to the drug one or morc times without any allergic reactions — ANS-vv fige what is the typical relationship between a drug's site of administration and site of action — ANS- WW they are usually somewhat removed from cach other what is CMAX — ANS— v 7 (G2RIBIASiia COnSOnEr acon Onlalmeasmnnalemnve which of the following is not a main concept in clinical pharmacology — ANS-Vv which of the following is not a route of drug administration — ANS- vv feast How arc intradermal drugs delivered? — ANS-WWby injection under the skin which of the following is not a type of non—stock sale — ANS-Vv BROkGrage what is another term for rebates — ANS- WW after—markct arrangements the PDMA is the presciption drug manufacturers associalion — ANS-vv ge a company that owns and opcrates three or fewer pharmacies is an —- ANS-VV which section of a drug's package insert in!formation covers Lhe usual dosage range — ANS—v vfGiSaEIOns ananusaee Drug labels must include indications and usage information, as well as contraindications. — ANS-VWfHue what should be included in the “description" section off a drug's package insert information — ANS—v [iSISfUg!s!BrenHe lay sais idl helestablishediane Exclusivily gives exclusive ,i8 granted by the FDA, and can run concurrently with a patent or not. — ANS- VV fie nee nes what differentiates exclusivity from a patent — ANS- VV BRGlusivibenOnIy, what is required of an invention for it to be worthy of patent protection —- ANS-v Vit must be novel, useful, and not obvious agencric drug is___ to the originator brand-name drug in dosage, strength, safcty, and quality — ANS-W W Bideduivalent which of the following is not required by the DA's Criteria for Equivalency — AKS- WW the drugs contain identical amounts off the same inactive ingredients A generic drug is ta the originatory brand-name drug in dosage, strength, safety, and quality — ANS- vv Bideguivalont what list is generally considered the most reliable source of information on therapcutically equivalent drug products — ANS- VV "Ap pEOVeGIOFUBIBEOGUGES which of the following is an Orange Book rating — ANS-vv RA what is the term for chemical equivalents which, when administered in the samc amaunts, will provide Lhe same biological ar physiological availability as measured by blood and urine levels — ANS-V WV BiGIOgiGaeguIvalOnES what term denotes a drug that is identical or biocquivalent to the originator brand-name drug in dosage form, safety, strength, route, quality, performance, characteristics, and intended use — ANS- vv Beneee what term denotes the dispensing of an unbranded gencric product for the product prescribed — ANS- 7 v QGHGHeISUDSIIEunION what is the duration off a patent challenge — ANS- vv iR0Mays Storage conditions for drug products are based on information supplied by the manufacturer — ANS-VWtruc medications are usually unaffected by changes in temperature, light, humidity, and other environmental factors — ANS-VW false In which cases can degraded drugs SOMETIMES still be used? — ANS-WAW when the amount off remaining drug has not fallen lower than 85-90% of thal stated on the label Drug recalls are almost always negotiated with the FDA beforchand. - ANS-Vv truc Which problem would NOT be improved by electronic prescribing systems? — ANS-WW none: patients "doclor—shopping" for controlled substances, pharmacists misreading prescriptions, physicians wasting time calling pharmacics what should you do if you recieve a shipment from your employer and you notice that there are twice as many samples as what is posted on the packing slip — ANS-WW call your sales manager to inform him/ her of the mistake and ask for instruclions pasted on the packing slip which area of drugs R&D has seen the largest cost increases — ANS-WW clinical trials on average, how long docs it take for a new drug to be developed (I.c., from the discovery of the initial compound to FDA approval) — ANS-WW10-15 years which of the following regulatory agencics is industry— based (I.c., run mainly by the companics themsclyes} — ANS-WWPharmaccutical rescarch and manufactures of america (PhRMA) which of the following factors has simplified the pharmaccutical R&D process — ANS-WW none: an intensive regulatory process, grawing demand in Lhe medical community for more complex data about pharmaccuticals, and the increasing number of precedures in Phase III trials the landmark I7DA Modernization Act of 1997 was a major step forward in enabling safe and cffective new drugs and biologics to be made available sooncr to paticnts — ANS-VWtruc according lo your manual, which lype of system is the best wal ta deliever healthcare — ANS-~WWa markct—based system how would increased pharmaccutical price controls affect the U.S. healthcare system — ANS-WWincrcascd price cantrols would stifle innovation which of the following invests a greater percentage of sales in research than the biotech sector — ANS-WW none: acrospace sector, communications sector, electronics sector whal was the intent of the Bayh—Doale Act and Stevenson—Wydler Technology Innovation Act — ANS-WW to hasten the commercialization of technologics that otherwise might not be used according to your manual, what did the G10 medicines group recently report about the pharmaccutical industry in the curopean union (EU) — ANS-Ww there is poor collaberation between publicly— and privatcly— funded research concerns which of the following docs not affect a drug's distribution to its targct tissucs — ANS-Ww the drug's lipid—solubility, the drug's polarity, the vascular nature of the drug's target tissuc— all these facots affect a drug's distribution to its target tissucs which of these medical terms means "Lo apply the drug on the skin surface" — ANS- WW transdermal Carcinogenicity studics are carried out to identify the tumor—causing potential of a drug. — ANS-Vwvtruc According to NIH cthical guidelines, which of the following is the most important criteria in selecting subjects for clinical studies? -— ANS-WW scientific objectives which statement aboul the IRB in incorrect - ANS-WeWthe members of the IRB/IEC must be experts in the topic of study Which phases of clinical studies are open label and which are blinded? — ANS-¢# Uphasc I and IV trials are often open label, but phase II and II are double blinded or at Icast blinded If it is not possible to measure the direct effects of a drug, what is used instead? — ANS-WW surrogate markers such as blood pressure and cholesterol levels which of the following is an observational study that first identifies a group of subject with a certain discase and a control group without the discasc, and then looks to back in time (c.g. via chart reviews) to find expasurce to risk factors — ANS-WWcasc—control study which measure of central tendency is the sum of all observations divided by the number of abservations — ANS-We#mcan which measurement describes the number of new events that occur during a specified period of time in a population at risk for the event (c.g. lung infections per year) — ANS-WWincidenee which of the following measures is used lo describe the variability of the populaton mcan — ANS-WW standard crror of the mcan which of the following terms denotes the extent to which a test actually measures what it is supposed to be measuring, or what we think it is measuring — ANS-¥v Vvailidily What are the Kaplan—Meier analysis and Cox proportional hazards analysis? — ANS-We¢ methods of survival analysis what scction of a clincal paper describes subjects’ entry and exclusion criteria — ANS- We mcthods which document sects out how a trial is to be conducted (I.c. the study's general design and operating features) — ANS—WW inclusion criteria when designing and performing clincal trials, several cthical constraintes must be considered, which of the following is NOT one af these ethical canstraints — ANS-WW scographic variations which of the following is a basic gene therapy technique — ANS—WWin vitro, in whihc paticnts' genctically faulted tissucs are removed, loaded with normal genes in vectors, and returned Lo the palients' bodies which statements about stem cclls is correct — ANS-Wv pluripotent stem cells can develop into many ccll types, but not a new individual Leukemia is a condition in which the bone marrow is unable Lo produce functional white blood cells to fight infection. - ANS-WVWtruc which of the following arc types of vectors used in gene therapy — ANS-Vv retroviruses which of the following is nal a type of stem cell - ANS-WWsemipotent Traditional vaccines are prepared in a number of ways. What way is NOT onc of them? — ANS-#Winsulin Effective drug therapy is a cost—elfective and highly valuable means of controlling total healthcare expenditures and improving quality of life. - ANS-¥o Viruc Drug Utilization Review (DUR) programs — ANS-Wdhave traditionally been used to ensure the appropriate, safe, and effective use of prescription drugs, but are increasingly shifting their focus to minimizing costs. DUR programs involve retrospective monitoring of physicians! prescribing patterns. - ANS-Vwvtruc A formulary is a list of prescription drugs approved by insurance coverage. — ANS-Vvitruc The history of drug formularies in the U.S. extends back to... - ANS-Ww¢ the american revolution which of these is not a type of formulary — ANS-WWAIl of these are types of formularics: A. aclosed three-tier formulary in which gencric drugs are listed on Tier 1 B. a five—ticr formulary that is supplemented by a step therapy pregram C. an open formulary that places few restrictions on coverage or access which of the following is not a recent formulary trend — ANS-We the repeal of hatch—-waxman What did the Hatch—-Waxman Act do? — ANS-Wemakc it casicr for gencric manufacturers Lo compete with R&D companies What is opportunity cost? — ANS-WW the valuse of a sacrificed alternative according lo your manual, Lhe three primary entilies Lhal fund pharmaceuticals are employers, the government (medicare and medicaid) and — ANS—WWindividuals which of these individuals would not be a member of a P&T committee — ANS-¥ Wa company's medical liason 
