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MIC 412LEC JAC: Fundamentals of Immunology (Winter 24)
Professor Amy Jacobs
University: University at Buffalo
Chapter 1 Quiz: Attempt 1- Score 100% (Highest Score)
Question 1: In addition to T cells, which cell type is required for initiation of all T cell–mediated immune responses?
a. Effector cells b. Memory cells c. Natural killer cells d. Antigen-presenting cells e. B lymphocytes Correct Answer: d. Antigen-presenting cells
Question 2: Which of the following cell types is required for all humoral immune responses?
a. Natural killer cells b. Dendritic cells c. Cytolytic T lymphocytes d. B lymphocytes e. Helper T lymphocytes
Correct Answer: d. B lymphocytes
Question 3: A previously healthy 8 - year-old boy is infected with an upper respiratory tract virus for the first time. During the first few hours of infection, which one of the following events occurs?
a. The adaptive immune system responds rapidly to the virus and keeps the viral infection under control. b. The innate immune system responds rapidly to the viral infection and keeps the viral infection under control. c. Passive immunity mediated by maternal antibodies limits the spread of infection. d. B and T lymphocytes recognize the virus and stimulate the innate immune response. e. The virus causes malignant transformation of respiratory mucosal epithelial cells, and the malignant cells are recognized by the adaptive immune system. Correct Answer: b. The innate immune system responds rapidly to the viral infection and keeps the viral infection under control.
Question 4: Antibodies and T lymphocytes are the respective mediators of which two types of immunity?
a. Specific and nonspecific b. Humoral and cell-mediated c. Passive and active
Question 7: Which of the following best describes clonal expansion in adaptive immune responses?
a. Increased number of different lymphocyte clones, each clone specific for a different antigen during the course of an infection b. Increased number of different lymphocyte clones, each clone specific for a different antigen during development of the immune system, before exposure to antigen c. Increased number of lymphocytes with identical specificities, all derived from a single lymphocyte due to nonspecific stimuli from the innate immune system d. Increased number of lymphocytes with identical specificities, all derived from a single lymphocyte stimulated by a single antigen e. Increased size of the lymphocytes of a single clone due to antigen-induced activation of the cells Correct Answer: d. Increased number of lymphocytes with identical specificities, all derived from a single lymphocyte stimulated by a single antigen
Question 8: Which of the following is a unique property of the adaptive immune system?
a. Highly diverse repertoire of specificities for antigens b. Self-nonself discrimination c. Recognition of microbial structures by both cell-associated and soluble receptors d. Protection against viral infections
e. Responses that have the same kinetics and magnitude on repeated exposure to the same microbe Correct Answer: a. Highly diverse repertoire of specificities for antigens
Question 9: B cells mature in the
a. bone marrow b. thymus c. liver d. brain e. pancreas Correct Answer: a. bone marrow
Question 10: The principal function of the immune system is:
a. defense against cancer b. repair of injured tissues c. defense against microbial infections d. prevention of inflammatory diseases e. protection against environmental toxins Correct Answer: c. defense against microbial infections
