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Antifungal and Asthma Drugs: Exam Q&A for Pharmacology Students, Exams of Advanced Education

University of Massachusetts - BostonAdvanced Education

A concise overview of various antifungal and asthma drugs, detailing examples, mechanisms of action (moa), and side effects. It covers tri-azole drugs like fluconazole and itraconazole, polyenes like amphotericin b, and echinocandins like caspofungin, explaining how each class inhibits fungal cell membrane synthesis or disrupts cell integrity. Additionally, it outlines asthma drugs such as beta 2 agonists, glucocorticoids, and monoclonal antibodies, describing their bronchodilatory and anti-inflammatory effects, along with potential side effects. This information is useful for medical and pharmacy students studying pharmacology and therapeutics. Structured as a series of questions and answers, making it easy to review key concepts and drug characteristics. It serves as a quick reference for understanding the pharmacological actions and clinical considerations of these medications, aiding in exam preparation and clinical practice.

Typology: Exams

2024/2025

Available from 05/15/2025

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MD3001 Drugs Exam Questions And
Accurate Answers
Tri-Azole Drug exmaples - Answer Fluconazole
Itraconazole
Voriconazole
Posaconazole
Fluconazole - Answer Antifungal
- Well absorbed orally
- treats neurological infection (penetrates into CSF)
- treats candiduria (unchanged in urine)
Itraconazole - Answer Antifungal
- require stomach acid to absorb
- hepatotoxic
- drug-drug interactions
Posaconazole - Answer Antifungal
- used for invasive fungal infections
Voriconazole - Answer Antifungal
- used for life threatening conditions
- drug-drug interactions
Fluconazole MOA - Answer inhibits biosynthesis of ergosterol which
is essential for fungi cell membrane
Polyenes examples - Answer Antifungal
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Download Antifungal and Asthma Drugs: Exam Q&A for Pharmacology Students and more Exams Advanced Education in PDF only on Docsity!

MD3001 Drugs Exam Questions And

Accurate Answers

Tri-Azole Drug exmaples - Answer Fluconazole Itraconazole Voriconazole Posaconazole Fluconazole - Answer Antifungal

  • Well absorbed orally
  • treats neurological infection (penetrates into CSF)
  • treats candiduria (unchanged in urine) Itraconazole - Answer Antifungal
  • require stomach acid to absorb
  • hepatotoxic
  • drug-drug interactions Posaconazole - Answer Antifungal
  • used for invasive fungal infections Voriconazole - Answer Antifungal
  • used for life threatening conditions
  • drug-drug interactions Fluconazole MOA - Answer inhibits biosynthesis of ergosterol which is essential for fungi cell membrane Polyenes examples - Answer Antifungal

Amphotericin B Nystatin Polyenes MOA - Answer Antifungal

  • binds with ergosterol and makes pores
  • ions leak and cell dies (K, Na, H, Cl) Flucytosine - Answer Antifungal
  • systemic yeast and fungal infections
  • often alongside amphotericin B Flucytosine MOA - Answer Antifungal
  • forms false nucleotide
  • disrupts nucleic acid and protein synthesis Echinocandin examples - Answer Caspofungin Micafungin Anidulafungin Echinocandins MOA - Answer Antifungal
  • inhibits beta (1,3) D-glucan synthase Echinocandins target - Answer Antifungal candida spp. (fungicidal) aspergillus spp. (fungistatic) Terbinafine - Answer Antifungal
  • dermatophyte infection of nails
  • ringworm Terbinafine side effects and cautions - Answer Antifungal

aminophylline monoclonal antibodies example - Answer Asthma Drugs Omalizumab Beta 2 agonists MOA - Answer Asthma Drugs causes relaxation of bronchial smooth muscle (bronchodilation) inhibits mast cell and leucocytes increases ciliary action (mucus clearance) Beta 2 agonist side effects - Answer Asthma Drugs sympathetic effects muscle pain hypokalemia hyperglycemia bronchospasm