Chem 120 Worksheet 14 (29 pts) Fall 2023
1. (9 pts) Rank the following fatty acids from lowest to highest melting point
a. A. Stearic acid (C18:0) B. Caprylic acid (C8:0) C. Lauric acid (C12:0) D. Myristic acid (C14:0)
Answer: ____ < ____ < ____ < ____
b. A. stearic acid (C18:0) B. linoleic acid (C18:2) C. linolenic acid (C18:3)
D. elaidic acid (C18:1 (trans)) E. oleic acid (C18:1)
Answer: ____ < ____ < _____ < ____ < ____
2. (3 pts) Which of these lipids is:
a. ____ a prostaglandin
b. ____ a leukotriene
c. ____ a thromboxane
3. (2 pts) How does aspirin relieves pain and
inflammation?
a. ____ by inhibiting 5-lipoxygenase and stopping leukotriene synthesis
b. ____ by inhibiting cyclooxygenase-2 and stopping arachidonic acid synthesis
c. ____ by inhibiting cyclooxygenase-1 and stopping prostaglandin synthesis
d. ____ by interfering with gastrointestinal processes
4. (2 pts) Drugs that interfere with leukotriene action:
a. ____ Inhibit leukotriene synthesis by inhibiting 5-lipoxygenase
b. ____ Inhibit leukotriene synthesis by inhibiting cyclooxygenase-2
c. ____ Inhibit leukotriene signaling by acting as leukotriene receptor antagonists
d. ____ Some do A and some do C
5. (3 pts) Look at the phospholipid below and indicate
a. Which part is hydrophilic?
b. Which part is hydrophobic
c. Where is the glycerol?
6. (2 pts) Which of the following statements about cholesterol are true
a. ____ cholesterol is obtained from the diet
b. ____ cholesterol is synthesized principally in the liver
c. ____ elevated serum cholesterol levels correlate with the risk of adverse cardiovascular events
d. ____ all of the above
BC
DA
c
BED
A
Es
I
V
hydrophilic
[
&
esscera
J
hydrophobic
v
