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Lasix Medication: Dosage, Side Effects, Interactions, and Warnings, Study notes of Medicine

Information about Lasix, a medication used to treat high blood pressure and fluid retention. It covers common questions about the use of Lasix tablets, oral solution, and injections, including when to take it, when not to take it, possible side effects, interactions with other medications, and warnings. It also includes information on how to store Lasix and its appearance.

What you will learn

  • What conditions is Lasix used to treat?
  • What are the side effects of taking Lasix?
  • What medications should not be taken with Lasix?

Typology: Study notes

2021/2022

Uploaded on 09/12/2022

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Lasix® and Lasix® High
Dose
(LAY-six)
Furosemide (Frusemide) (fur-o-za-MIDE / froo-za-MIDE)
Consumer Medicine Information (CMI)
What is in this leaflet
This leaflet answers some common
questions about Lasix oral medicines
(tablets, oral solution) and injections.
It does not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you taking this medicine
against the benefits they expect it
will have for you.
If you have any concerns about
taking this medicine, ask your
doctor or pharmacist.
Keep this leaflet with the medicine.
You may need to read it again.
What Lasix is used for
Lasix contains furosemide
(frusemide), which belongs to a
family of drugs called diuretics. A
diuretic helps reduce the amount of
excess fluid in the body by increasing
the amount of urine produced.
Lasix is used to treat swelling of the
ankles, feet, legs or even the brain or
lungs. This swelling is called oedema
and can occur in some heart, lung,
liver or kidney conditions.
Lasix may be used in some patients
with more serious kidney problems
who may have some fluid retention.
Lasix may also be used to lower high
blood pressure (which is also called
hypertension).
Everyone has blood pressure. This
pressure helps move your blood
around your body. Your blood
pressure may vary at different times
of the day, depending on how busy or
worried you are. You have
hypertension (high blood pressure)
when your blood pressure stays
higher than is needed, even when you
are calm and relaxed.
If high blood pressure is not treated it
can lead to serious health problems,
including stroke, heart disease and
kidney failure.
Lasix may be taken alone or in
combination with other medicines to
treat your condition.
Your doctor may have prescribed
Lasix for another purpose.
Ask your doctor if you have any
questions about why it has been
prescribed for you.
This medicine is only available with
a doctor's prescription.
This medicine is not addictive.
Before you take it
When you must not take it
Do not take Lasix if you have:
certain liver and kidney
problems
no production or no passing of
urine
low blood pressure
(hypotension)
low sodium levels in your blood
low potassium levels in your
blood
dehydration
jaundice or history of jaundice
in newborns or infants
hepatic coma or precoma
Do not take Lasix if you are
allergic to:
this medicine or any of the
ingredients listed at the end of
this leaflet
medicines called sulfonamides
(eg. some types of antibiotics
which are also referred to as
'sulfur antibiotics') or
sulfonylureas which are
medicines which can be used to
treat diabetes
Some symptoms of an allergic
reaction include skin rash, itching,
shortness of breath or swelling of the
face, lips or tongue, which may cause
difficulty in swallowing or breathing.
Do not take Lasix if you are
pregnant.
Do not take Lasix if you are breast-
feeding or planning to breast-feed.
The active drug, furosemide
(frusemide), passes into breast milk
and there is a possibility your baby
may be affected.
Do not take it after the expiry date
(EXP) printed on the pack.
LASIX® AND LASIX® HIGH DOSE 1
pf3
pf4
pf5

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Lasix

and Lasix

High

Dose

(LAY-six)

Furosemide (Frusemide) (fur-o-za-MIDE / froo-za-MIDE)

Consumer Medicine Information (CMI)

What is in this leaflet

This leaflet answers some common questions about Lasix oral medicines (tablets, oral solution) and injections.

It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks of you taking this medicine against the benefits they expect it will have for you.

If you have any concerns about taking this medicine, ask your doctor or pharmacist.

Keep this leaflet with the medicine.

You may need to read it again.

What Lasix is used for

Lasix contains furosemide (frusemide), which belongs to a family of drugs called diuretics. A diuretic helps reduce the amount of excess fluid in the body by increasing the amount of urine produced.

Lasix is used to treat swelling of the ankles, feet, legs or even the brain or lungs. This swelling is called oedema and can occur in some heart, lung, liver or kidney conditions.

Lasix may be used in some patients with more serious kidney problems who may have some fluid retention.

Lasix may also be used to lower high blood pressure (which is also called hypertension). Everyone has blood pressure. This pressure helps move your blood around your body. Your blood pressure may vary at different times of the day, depending on how busy or worried you are. You have hypertension (high blood pressure) when your blood pressure stays higher than is needed, even when you are calm and relaxed. If high blood pressure is not treated it can lead to serious health problems, including stroke, heart disease and kidney failure. Lasix may be taken alone or in combination with other medicines to treat your condition. Your doctor may have prescribed Lasix for another purpose. Ask your doctor if you have any questions about why it has been prescribed for you. This medicine is only available with a doctor's prescription. This medicine is not addictive.

Before you take it

When you must not take it

Do not take Lasix if you have:

- certain liver and kidney problems - no production or no passing of urine - low blood pressure (hypotension) - low sodium levels in your blood - low potassium levels in your blood - dehydration - jaundice or history of jaundice in newborns or infants - hepatic coma or precoma Do not take Lasix if you are allergic to: - this medicine or any of the ingredients listed at the end of this leaflet - medicines called sulfonamides (eg. some types of antibiotics which are also referred to as 'sulfur antibiotics') or sulfonylureas which are medicines which can be used to treat diabetes Some symptoms of an allergic reaction include skin rash, itching, shortness of breath or swelling of the face, lips or tongue, which may cause difficulty in swallowing or breathing. Do not take Lasix if you are pregnant. Do not take Lasix if you are breast- feeding or planning to breast-feed. The active drug, furosemide (frusemide), passes into breast milk and there is a possibility your baby may be affected. Do not take it after the expiry date (EXP) printed on the pack.

If you take it after the expiry date has passed, it may not work as well.

Do not take Lasix if the packaging is torn or shows signs of tampering.

Before you start to take it

Tell your doctor if you have allergies to:

- any of the ingredients listed at **the end of this leaflet

  • any other medicines called** **sulfonamides or sulfonylureas
  • any other substances, such as** foods, preservatives or dyes.

Tell your doctor if you are pregnant or intend to become pregnant.

Like most medicines of this kind, Lasix is not recommended to be used during pregnancy. If there is a need to consider Lasix during your pregnancy, your doctor will discuss the risks and benefits of taking it if you are pregnant.

Tell your doctor if you are breast- feeding or planning to breast-feed.

Lasix passes into breast milk and there is a possibility your baby may be affected. Your doctor will discuss the risks and benefits of taking it if you are breast-feeding or planning to breast-feed.

Tell your doctor if you have or have had any medical conditions, especially the following:

**- liver problems

  • kidney problems
  • heart problems
  • high cholesterol levels
  • asthma
  • diabetes
  • gout, a disease with painful,** **swollen joints
  • passing less urine than is** **normal for you
  • difficulty passing urine
  • no production or no passing of** **urine
  • prostate problems** - Systemic Lupus Erythematosus (SLE), a disease affecting the skin, joints and kidneys Tell your doctor if you are on a salt restricted diet. If you have not told your doctor about any of the above, tell them before you take Lasix.

Taking other medicines

Tell your doctor or pharmacist if you are taking any other medicines, including any that you buy without a prescription from your pharmacy, supermarket or health food store. Some medicines should not be taken with Lasix. This includes large amounts of laxatives. Some medicines may interfere with Lasix. These include:

  • certain other fluid tablets or diuretic medicines
  • medicines used to treat high blood pressure and some other heart conditions, especially ACE inhibitors or angiotensin receptor antagonists
  • digoxin and other medicines used to treat heart failure
  • non-steroidal anti-inflammatory drugs (NSAIDs) and aspirin, medicines used to relieve pain, swelling and other symptoms of inflammation, including arthritis
  • methotrexate, a medicine used to treat arthritis and some types of cancer
  • probenecid, a medicine used to treat gout
  • medicines used to relax muscles before or during surgery
  • lithium, a medicine used to treat mood swings and some types of depression
  • medicines used in emergency situations such as adrenaline (epinephrine) and noradrenaline (norepinephrine)
  • cisplatin, a medicine used to treat cancer - theophylline, a medicine used to treat asthma - certain antibiotics, especially cephalosporins and aminoglycosides - amphotericin, a medicine used to treat fungal infections - barbiturates, medicine used to treat epilepsy, to produce calmness, or to help you sleep - narcotic/strong pain killers such as codeine and morphine - insulin and tablets used to treat diabetes - sucralfate, a medicine used to treat stomach ulcers - anticonvulsant medicines such as chloral hydrate or phenytoin - corticosteroids such as cortisone, prednisone or dexamethasone - medicines used to treat thyroid conditions - risperidone, an antipsychotic medication used to schizophrenia - medicines used during scans to see the images of your body These medicines may be affected by Lasix, or may affect how well it works. You may need to use different amounts of your medicine, or take different medicines. Your doctor or pharmacist will advise you. You should not eat large amounts of liquorice when you are taking Lasix. Your doctor or pharmacist has more information on medicines to be careful with or to avoid while taking Lasix.

How to take it

How much to take

Follow the directions given to you by your doctor and pharmacist carefully. These directions may differ from the information contained in this leaflet.

- passing less urine than normal

If you experience these symptoms, you may be dehydrated because you are losing too much water.

Make sure you drink enough water during any exercise and during hot weather when you are taking Lasix, especially if you sweat a lot.

If you do not drink enough water while taking Lasix, you may feel faint or light-headed or sick. This is because your blood pressure is dropping suddenly and you are dehydrating. If you continue to feel unwell, tell your doctor.

If you are about to have any blood tests, tell your doctor that you are taking Lasix.

There may be some interference with the results of these tests.

If you are taking Lasix to treat high blood pressure, make sure you have your blood pressure checked when your doctor says to make sure Lasix is working properly.

Things you must not do

Do not give this medicine to anyone else, even if they have the same condition as you.

Do not use this medicine to treat any other complaints unless your doctor tells you to.

Do not stop taking Lasix, or change the dosage, without checking with your doctor.

Things to be careful of

If you feel light-headed, dizzy or faint, get up slowly when getting out of bed or standing up.

You may feel light-headed or dizzy when you begin to take Lasix. This is because your blood pressure is falling suddenly. Standing up slowly, especially when you get up from beds or chairs, will help your body get used to the change in position and blood pressure. If this problem continues or gets worse, talk to your doctor.

Be careful driving or operating machinery until you know how Lasix affects you. Diuretic medicines may cause dizziness or light-headedness in some people. Make sure you know how you react to your medicine before you drive a car, operate machinery, or do anything else that could be dangerous if you are dizzy or light- headed. If this occurs do not drive. If you drink alcohol or take strong painkillers, dizziness or light- headedness may be worse. The effects of alcohol could be made worse while taking Lasix. It is not recommended that you drink alcohol while taking Lasix. There are two Lasix Oral Solution formulations available. Lasix oral solution (not requiring refrigeration) contains ethanol (alcohol) 0.5g per 5ml dose, which is equivalent to 12.7ml of beer or 5.3ml of wine per 5ml dose. If you are taking Lasix for a long period of time, you should check with your doctor to determine whether or not you should eat more potassium-containing foods or take potassium supplements. However, increasing the amount of potassium in your diet may not be necessary and could be harmful. Check with your doctor. Lasix may cause your skin to become more sensitive to the sun. If this happens you should take care to wear protective clothing including a hat and sun block when you are outside.

Things that may help your

condition

Some self-help measures suggested below may help your condition.

  • Alcohol - your doctor may advise you to limit your alcohol intake
  • diet - eat a healthy diet which includes plenty of fresh vegetables, fruit, bread, cereals

and fish. Also eat less fat and sugar

  • exercise - regular exercise helps reduce blood pressure and helps the heart get fitter, but it is important not to overdo it. Walking is a good exercise, but try to find a route that is fairly flat. Before starting any exercise, ask your doctor about the best kind of program for you
  • salt - if you have high blood pressure, your doctor may advise you to watch the amount of salt in your diet. To reduce your salt intake you should avoid using salt in cooking or at the table
  • smoking - your doctor may advise you to stop smoking or at least to cut it down
  • weight - your doctor may suggest that you lose some weight to help lower your blood pressure and help lessen the amount of work your heart has to do. Some people may need a dietician's help to lose weight. Talk to your doctor or pharmacist about these measures and for more information.

Side effects

All medicines have some unwanted side effects. Sometimes they are serious, but most of the time they are not. Your doctor has weighed the risks of using this medicine against the benefits they expect it will have for you. Do not be alarmed by this list of possible side effects. You may not experience any of them. Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Lasix. Lasix helps most people with high blood pressure or fluid retention, but it may have unwanted side effects in a few people.

Tell your doctor if you notice any of the following and they worry you:

  • very dry mouth or unusual thirst
  • weight loss
  • weakness or tiredness
  • numbness or tingling in the hands and/or feet
  • calf muscle spasms
  • muscle pains or cramps
  • restlessness
  • drowsiness or a lack of energy
  • dizziness or light-headedness
  • headache
  • fever
  • vomiting or nausea
  • diarrhoea
  • blurred or impaired vision
  • unusual bleeding or bruising under the skin
  • ringing or buzzing in the ears
  • confusion

These are more common side effects of Lasix. Mostly they are mild or short-lived.

Tell your doctor as soon as possible if you notice any of the following:

  • irregular or fast heart beat
  • passing less urine than is normal for you
  • severe stomach pain, often with nausea or vomiting
  • severe dizziness or a spinning sensation
  • increased sensitivity to sunlight
  • flaking or peeling of the skin
  • symptoms of anaemia such as tiredness, being short of breath when exercising, dizziness and looking pale
  • frequent infections such as fever, severe chills, sore throat or mouth ulcers
  • bleeding or bruising more easily than normal, nose bleeds
  • loss of control of your bladder or bowels (incontinence) - gout, a disease with painful, swollen joints - deafness or ringing in the ears These may be serious side effects of Lasix. You may need urgent medical attention. Serious side effects are uncommon. If any of the following happen, tell your doctor immediately or go to Accident and Emergency at your nearest hospital: - sudden signs of allergy such as rash, itching or hives (pinkish, itchy raised areas) on the skin, swelling of the face, lips, tongue or other parts of the body, shortness of breath, wheezing or trouble breathing - chest pain - fainting or having a rapid, weak pulse - lockjaw - red, often itchy spots similar to the rash seen with measles which starts on the limbs and sometimes on the face and body. The spots may blister and may progress to form raised red, pale-centred marks. Those affected may have fever, sore throat, headache with or without diarrhoea - yellowing of the skin and/or eyes (jaundice) These are serious side effects. You may need urgent medical attention or hospitalisation. These side effects are very rare. Tell your doctor or pharmacist if you notice anything else that is making you feel unwell. Other side effects not listed above may occur in some people. Ask your doctor or pharmacist to answer any questions you may have.

After using it

If you have any queries about any aspect of your medicine, or any questions regarding the

information in this leaflet, discuss them with your doctor or pharmacist.

Storage

Keep your Lasix tablets or oral solution in the bottle until it is time to take them. If you store your Lasix tablets or oral solution out of the container they may not keep well. Keep your Lasix tablets in a cool dry place where the temperature stays below 25°C. There are two Lasix Oral Solution formulations available. Refer to product label for instructions regarding storage conditions. Do not store Lasix or any other medicine in the bathroom, near a sink, or on a windowsill. Do not leave it in the car. Heat and damp can destroy some medicines. Keep it where children cannot reach it. A locked cupboard at least one-and- a-half metres above the ground is a good place to store medicines. Lasix injection is usually stored in the pharmacy or on the ward. The injection is kept in a cool dry place, protected from light, where the temperature stays below 25°C.

Disposal

If your doctor tells you to stop taking Lasix or the medicine has passed its expiry date, ask your pharmacist what to do with any that is left over. Return any unused medicine to your pharmacist.

Product description

What it looks like

Lasix M 20 mg tablets: white round tablets, marked with "DLF" on one