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Material Type: Exam; Professor: Deis; Class: 694 - INTRO BIOCHEM&MOLBIO; Subject: MOL BIO & BIOCHEM; University: Rutgers University; Term: Fall 2001;
Typology: Exams
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Biochemistry 694:301 Name___________________________ Second Test Dr. Deis Last 5 digits of SSN _______________ Thu. Oct. 25, 2001 Row Letter ____ Seat Number ______
This exam consists of two parts. Part I is multiple choice. Each of these 25 questions is worth two points. Answer the Part I questions on this sheet, below. Answer the Part II questions on the question pages.
Please use BLOCK CAPITAL letters like this --- A, B, C, D, E. Not lowercase!
Part I Total _______
Part II:
II-1 _______ II-2 _______ II-3 _______ II-4 _______ II-5 _______
Part II Total _______
Total, I & II _______
20.* Interpret the "chair" structure shown below. What is the name of the sugar represented? A. alpha-D-Mannose D. beta-D-Allose B. alpha-D-Glucose E. beta-D-Ribose C. alpha-D-Galactose
24.* The graph below represents the kinetics of PFK-I when F6P is held constant and ATP is varied. The lines marked "+" show the kinetics in the presence of what? A. cyclic AMP D. Glucose 6 P B. Calcium ion E. Fru-2,6-BP C. 2,3 BPG
PART II Answer these questions here on the question pages.
(3)
b. Draw a sketch which illustrates the Fluid Mosaic Model of membrane structure.
(2)
c. Where is Acetylcholinesterase located? Why is it such a fast acting enzyme? Be as specific as you can.
(3)
d. Briefly describe the process for an Excised Patch Mode Patch-Clamp Conductance experiment. What would one be trying to observe by doing this?
(2)
(3)
b. What genes are involved in generation of antibody diversity? Diagram the germ-line DNA as done in class and in the text. Label the gene segments and tell what the abbreviations stand for.
(3)
c. Distinguish functionally between Class I and Class II MCH proteins. For a complete answer you have to discuss various T-cells, etc.
(4)
4.* a. What cofactors are represented below?
(4)
b. Draw the disaccharide D-mannopyranosyl α1-4 β D-xylulofuranose in the Haworth projection. For partial credit just draw D-Mannose and D-Xylulose in the Fischer projection.
(4)
c. Draw the alpha and beta anomers of D-Fructopyranose (2)