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A comprehensive overview of immunology and infectious diseases relevant to oral health care workers. It covers key concepts such as antigens, antibodies, immunity, and various infectious diseases like hepatitis b, tuberculosis, and hiv. Definitions, explanations, and exercises to enhance understanding. It is a valuable resource for students and professionals in the field of oral health.
Typology: Exams
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Autogenous |infection |- |correct |answer |✔self |generated |infection |that |occurs |if |the |conditions |are |right |for |the |microorganism
Resistance |- |correct |answer |✔the |ability |to |produce |antibodies |in |response |to |an |antigen |or |pathogen |may |be |permanent |or |transient
Antigen |- |correct |answer |✔substance |that |induces |a |specific |immune |response |in |reaction |to |the |antibody
Antibody |- |correct |answer |✔a |protein |molecule |in |response |to |an |antigen
How |do |antigens |and |antibodies |create |resistance? |- |correct |answer |✔happens |naturally |after |antigen-antibody |response, |helps |protect |against |disease |can |be |PERMANENT |or |TRANSIENT
Immunity |- |correct |answer |✔the |resistance |a |person |has |against |a |foreign |substance
Cell |mediated |immunity |- |correct |answer |✔no |anti-body |production |( |immune |system |comes |to |the |rescue |with |T |cells) |NO |MEMORY
Humoral |immunity |- |correct |answer |✔produces |antibodies |that |target |specific |pathogens |and |produces |histamine |in |the |body |MEMORY |( |B |cells)
Natural |Immunity |- |correct |answer |✔contains|both |active |and |passive |immunity
Natural |Active |immunity |- |correct |answer |✔acquired |by |contracting |a |disease |( |ex |chicken |pox)
Natural |Passive |immunity |- |correct |answer |✔temporary |and |short |term, |(ex |from |fetus |to |mother)
Artificial |immunity |- |correct |answer |✔contains |both |active |and |passive |immunity
Artificial |active |immunity |- |correct |answer |✔vaccinations |, |long |term |, |just |enough |for |antigen/antibody |response
Artificial |passive |immunity |- |correct |answer |✔immunity |with |a |short |duration |from |ready |made |antibodies |(ex |gammaglobulin |in |Hep |B |post-exposure)
Common |immunizations |for |oral |health |care |workers |- |correct |answer |✔Hep |B- |series |of |three |then |check |for |titer |
Flu |Shot- |annual |
MMR
Tetanus
Tetanus |- |correct |answer |✔vaccine- | 1 |dose |when |child, |then |another |every | 10 |years
passive |immunity |immune |response |from |HB |vaccine
Incubation |period |of |HBV |- |correct |answer |✔4-25 |weeks
HepB |surface |agent--> |HBsAG |can |be |detected |as |soon |as | 30 |days |
60% |of |HBV |victims |have |subclinical |symptoms
Transmission |routes |of |HBV |- |correct |answer |✔blood( |has |a |carrier |state), |percutaneous, |perinatal |exposure, |sexual, |IV |drug |users |and |blood |transfusions
Tuberculosis |- |correct |answer |✔no |vaccine |available|yet, |TB |test |should |be |done |yearly, |** |very |contagious |& |hard |to |get |rid |of
TB |drugs |- |correct |answer |✔-takes |direct |observe |therapy |(DOT) |for |6-9 |months
-Rifampin |and |isoniazid |for |6-9|months
Disease |process |of |TB |- |correct |answer |✔If |enough |M. |tuberculosis |bacteria |reaches |the |alveoli |of |the |lung |and |begins |to |multiply
Mantoux |test |- |correct |answer |✔PPD |test- |purified |protein |derivative
-skin |test |read |48-72 |hours |after |injection
10mm |or |greater |= |positive |infection
Epstein-Barr |Virus |(EBV) |- |correct |answer |✔Herpes |virus |type | 4
affects |children, |usually |no |symptoms |in |adults
MONONUCLEOSIS
-can |be |latent |and |reactive
Varicella |Zoster |Virus |(VZV) |- |correct |answer |✔Herpes|virus |type | 3
-causes |chicken |pox |and |shingles |as |an |adult
-60 |and |older |can |get |vaccine |
-Droplet |infection, |and |is |spread |through |bloodstream |to |skin |and |organs
-highly |contagious
Seroconversion |- |correct |answer |✔Conversion |of |blood |after |exposure |to |etiologic |agent(s) |
negative= |seronegative
positive= |seropositive
HSV-1 |- |correct |answer |✔Herpes |simplex |virus | 1 |
-causes |infection |of |mouth, |skin, |eyes, |genital |and |those |with |compromised |immune |system |
-may |be |widespread |(systemic) |
50% |of |population |has |had |HAV
HCV |- |correct |answer |✔Hepatitis |C |infection |
Used |to |be |called |NON |A |and |NON |B |
-no |vaccine!
-blood |borne |
60-70% |of |people|infected |have |no |symptoms
-can |take |up |to | 20 |years |to |develop--first |sign |is |liver |disease
Transmission |of |HCV |- |correct |answer |✔repeated |exposure |through |IV |drug |use |and |tattoos
Incubation |period |of |HCV |- |correct |answer |✔2-25 |weeks
90% |of |people |who |take |active |antiviral |can |cure|hep |C
AAT |--> |active |antiviral |therapy
HVD |(delta |hepatitis) |- |correct |answer |✔Hepatitis |D
-can |only |exist |if |HBV |is |present |
-transmission |is |the |same |as |HBV |but |occurs |with |multiple |exposures |
-very |immunocompromised |( |often |HIV-AIDS |positive |will |develop |HVD) |
-delta |antigen |superimposes |oh |HBsAG |
-symptoms |same |has |HBV |- |very |fatal
HEV |(enteric |hepatitis) |- |correct |answer |✔Transmitted |person |to |person |or |through |contaminated |water
-no |chronic |state, |no |vaccine
-prevent |by |hand |washing
-rare |in |this |country, |more |common |in |3rd |world
HIV |- |correct |answer |✔Human |Immunodeficiency |Virus
AIDS |- |correct |answer |✔Acquired |immunodeficiency |syndrome |caused |by |HIV |(when |person |has | 1 |or |more |AIDS |related |indicators)
ARC= |Aids |related |complex, |patient |exhibits |classic |symptoms: |diarrhea, |unexplained |weight |loss |* |first |symptoms |of |aids |
(A) |Primary |Prevention | → |person |is |NOT |infected |(I.E. |abstinence, |limit |# |of |sex |partners, |condoms, |infection |control, |avoid |blood-contaminated |needles)
(B) |Secondary |Prevention | → |person |is |already |infected |(I.E. |get |tested, |monotherapy |or |combined |drug |treatment |for |mothers)
HIV |routes |of |transmission |- |correct |answer |✔blood, |semen, |vaginal |secretions, |breast |milk |* |not |through |tears |or |sweat
-HIV |is |higher |now |than | 2007 |
saliva |is |not |documented |
**95% |of |people |infected |will |seroconvert |within | 6 |months
( |6-12 |weeks |after |initial |infection)
Early |HIV |- |Category |I |- |correct |answer |✔CD4 |count |is |greater |than |500cells/mm
symptoms: |lymphadenopathy, |skin |lesions, |herpes |simplex |labials(oral |herpes), |hairy |leukoplakia |(hairy |tongue)
Intermediate |Stage |of |HIV |-Category |II |- |correct |answer |✔CD4 |count |200- |cells/mm
symptoms: |skin |lesions, |oral |lesions( |candidiasis-- |a |predictor |for |(PCP) |pneumocystic |carinii |pneumonia) |fever, |weight |loss, |headaches, |oral |lesions |** |leading |cause |of |death |is |PCP
Late |stage |of |HIV- |Category |III |- |correct |answer |✔CD4 |count |50-200 |cells/mm
Symptoms |include |AIDS |Indicator |Conditions: |
-opportunistic |infections- |microorganisms |are |capable |of |taking |over |a |immunocompromised |person |(wouldn't |happen |in |healthy |person) |
-Constitutional |Disease- |AKA |HIV |wasting |syndrome(fever, |weight |loss, |anemia, |weakness, |dementia, |degeneration |of |body) |
-Encephalophathy- |organic |mental |disorders |( |poor |memory, |depression, |motor |dysfunction) |
-Neoplasms |- |Kapsosi's |sarcoma, |brain |cancer, |hodgkins |lymphoma
Cytomegalovirus |- |correct |answer |✔herpesvirus |type | 5 | → |cause |cytomegalic |inclusion |disease, |found |in |newborns |& |immunocompromised
Primary |Herpetic |Gingivostomatitis |- |correct |answer |✔-first |outbreak |of |Herpes |Simplex | 1 |( |mostly |children) |
-may |present |a |multi-blister |rash |intraorally |from |the |lips |back |to |the |throat
-Very |painful |and |often |child |cannot |eat
-Takes |7-10 |days |to |clear |
Herpetic |Whitlow |- |correct |answer |✔herpes |on |the |finger |- |seen |years |ago |when |gloves |were |not |worn |( |may |be |simplex | 1 |or |2)
Creutzfeldt- |Jakob |disease |- |correct |answer |✔Known |as |CJD |or |vCJD |
-prion |disease |causing |spongiform |encephalopathies--> |pirons |are |abnormal |pathofens |that |distroy |brain |tissue |
( |belongs |to |human |and |animal |disease |* |bovine |disease) |
-rapid |dementia, |muscle |jerks
Post |exposure |plan |- |correct |answer |✔HBV-exposure | → |high-titer |gammaglobulin |(HBIG |= |anti-HB |immune |serum |globulin)