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Immunology and Infectious Diseases: A Comprehensive Guide for Oral Health Care Workers, Exams of Medicine

A comprehensive overview of immunology and infectious diseases relevant to oral health care workers. It covers key concepts such as antigens, antibodies, immunity, and various infectious diseases like hepatitis b, tuberculosis, and hiv. Definitions, explanations, and exercises to enhance understanding. It is a valuable resource for students and professionals in the field of oral health.

Typology: Exams

2024/2025

Available from 01/23/2025

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Autogenous |infection |- |correct |answer |self |generated |infection |that |occurs |if
|the |conditions |are |right |for |the |microorganism
Resistance |- |correct |answer |the |ability |to |produce |antibodies |in |response |to
|an |antigen |or |pathogen |may |be |permanent |or |transient
Antigen |- |correct |answer |substance |that |induces |a |specific |immune |response
|in |reaction |to |the |antibody
Antibody |- |correct |answer |a |protein |molecule |in |response |to |an |antigen
How |do |antigens |and |antibodies |create |resistance? |- |correct |answer |happens
|naturally |after |antigen-antibody |response, |helps |protect |against |disease |can |be
|PERMANENT |or |TRANSIENT
Immunity |- |correct |answer |the |resistance |a |person |has |against |a |foreign
|substance
Cell |mediated |immunity |- |correct |answer |no |anti-body |production |( |immune
|system |comes |to |the |rescue |with |T |cells) |NO |MEMORY
Humoral |immunity |- |correct |answer |produces |antibodies |that |target |specific
|pathogens |and |produces |histamine |in |the |body |MEMORY |( |B |cells)
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Autogenous |infection |- |correct |answer |✔self |generated |infection |that |occurs |if |the |conditions |are |right |for |the |microorganism

Resistance |- |correct |answer |✔the |ability |to |produce |antibodies |in |response |to |an |antigen |or |pathogen |may |be |permanent |or |transient

Antigen |- |correct |answer |✔substance |that |induces |a |specific |immune |response |in |reaction |to |the |antibody

Antibody |- |correct |answer |✔a |protein |molecule |in |response |to |an |antigen

How |do |antigens |and |antibodies |create |resistance? |- |correct |answer |✔happens |naturally |after |antigen-antibody |response, |helps |protect |against |disease |can |be |PERMANENT |or |TRANSIENT

Immunity |- |correct |answer |✔the |resistance |a |person |has |against |a |foreign |substance

Cell |mediated |immunity |- |correct |answer |✔no |anti-body |production |( |immune |system |comes |to |the |rescue |with |T |cells) |NO |MEMORY

Humoral |immunity |- |correct |answer |✔produces |antibodies |that |target |specific |pathogens |and |produces |histamine |in |the |body |MEMORY |( |B |cells)

Natural |Immunity |- |correct |answer |✔contains|both |active |and |passive |immunity

Natural |Active |immunity |- |correct |answer |✔acquired |by |contracting |a |disease |( |ex |chicken |pox)

Natural |Passive |immunity |- |correct |answer |✔temporary |and |short |term, |(ex |from |fetus |to |mother)

Artificial |immunity |- |correct |answer |✔contains |both |active |and |passive |immunity

Artificial |active |immunity |- |correct |answer |✔vaccinations |, |long |term |, |just |enough |for |antigen/antibody |response

Artificial |passive |immunity |- |correct |answer |✔immunity |with |a |short |duration |from |ready |made |antibodies |(ex |gammaglobulin |in |Hep |B |post-exposure)

Common |immunizations |for |oral |health |care |workers |- |correct |answer |✔Hep |B- |series |of |three |then |check |for |titer |

Flu |Shot- |annual |

MMR

Tetanus

Tetanus |- |correct |answer |✔vaccine- | 1 |dose |when |child, |then |another |every | 10 |years

passive |immunity |immune |response |from |HB |vaccine

  • |Immune

Incubation |period |of |HBV |- |correct |answer |✔4-25 |weeks

HepB |surface |agent--> |HBsAG |can |be |detected |as |soon |as | 30 |days |

60% |of |HBV |victims |have |subclinical |symptoms

Transmission |routes |of |HBV |- |correct |answer |✔blood( |has |a |carrier |state), |percutaneous, |perinatal |exposure, |sexual, |IV |drug |users |and |blood |transfusions

Tuberculosis |- |correct |answer |✔no |vaccine |available|yet, |TB |test |should |be |done |yearly, |** |very |contagious |& |hard |to |get |rid |of

  • |if |positive |patient |must |have |a |chest |x-ray |to |determine |if |tubercle |bacillus |is |in |the |lungs |( |creates |scar |tissue)

TB |drugs |- |correct |answer |✔-takes |direct |observe |therapy |(DOT) |for |6-9 |months

-Rifampin |and |isoniazid |for |6-9|months

Disease |process |of |TB |- |correct |answer |✔If |enough |M. |tuberculosis |bacteria |reaches |the |alveoli |of |the |lung |and |begins |to |multiply

Mantoux |test |- |correct |answer |✔PPD |test- |purified |protein |derivative

-skin |test |read |48-72 |hours |after |injection

10mm |or |greater |= |positive |infection

Epstein-Barr |Virus |(EBV) |- |correct |answer |✔Herpes |virus |type | 4

affects |children, |usually |no |symptoms |in |adults

MONONUCLEOSIS

  • |spread |by |saliva |or |blood, |"kissing |disease"

-can |be |latent |and |reactive

Varicella |Zoster |Virus |(VZV) |- |correct |answer |✔Herpes|virus |type | 3

-causes |chicken |pox |and |shingles |as |an |adult

-60 |and |older |can |get |vaccine |

-Droplet |infection, |and |is |spread |through |bloodstream |to |skin |and |organs

-highly |contagious

Seroconversion |- |correct |answer |✔Conversion |of |blood |after |exposure |to |etiologic |agent(s) |

negative= |seronegative

positive= |seropositive

HSV-1 |- |correct |answer |✔Herpes |simplex |virus | 1 |

-causes |infection |of |mouth, |skin, |eyes, |genital |and |those |with |compromised |immune |system |

-may |be |widespread |(systemic) |

  • |causes |viral |oral |diseases |ex: |primary |herpetic |gingivostomatitis |and |fever |blisters

50% |of |population |has |had |HAV

HCV |- |correct |answer |✔Hepatitis |C |infection |

Used |to |be |called |NON |A |and |NON |B |

-no |vaccine!

-blood |borne |

60-70% |of |people|infected |have |no |symptoms

-can |take |up |to | 20 |years |to |develop--first |sign |is |liver |disease

Transmission |of |HCV |- |correct |answer |✔repeated |exposure |through |IV |drug |use |and |tattoos

Incubation |period |of |HCV |- |correct |answer |✔2-25 |weeks

90% |of |people |who |take |active |antiviral |can |cure|hep |C

AAT |--> |active |antiviral |therapy

HVD |(delta |hepatitis) |- |correct |answer |✔Hepatitis |D

-can |only |exist |if |HBV |is |present |

-transmission |is |the |same |as |HBV |but |occurs |with |multiple |exposures |

-very |immunocompromised |( |often |HIV-AIDS |positive |will |develop |HVD) |

-delta |antigen |superimposes |oh |HBsAG |

-symptoms |same |has |HBV |- |very |fatal

HEV |(enteric |hepatitis) |- |correct |answer |✔Transmitted |person |to |person |or |through |contaminated |water

-no |chronic |state, |no |vaccine

-prevent |by |hand |washing

-rare |in |this |country, |more |common |in |3rd |world

HIV |- |correct |answer |✔Human |Immunodeficiency |Virus

AIDS |- |correct |answer |✔Acquired |immunodeficiency |syndrome |caused |by |HIV |(when |person |has | 1 |or |more |AIDS |related |indicators)

ARC= |Aids |related |complex, |patient |exhibits |classic |symptoms: |diarrhea, |unexplained |weight |loss |* |first |symptoms |of |aids |

  1. |Prevention:

(A) |Primary |Prevention | |person |is |NOT |infected |(I.E. |abstinence, |limit |# |of |sex |partners, |condoms, |infection |control, |avoid |blood-contaminated |needles)

(B) |Secondary |Prevention | |person |is |already |infected |(I.E. |get |tested, |monotherapy |or |combined |drug |treatment |for |mothers)

HIV |routes |of |transmission |- |correct |answer |✔blood, |semen, |vaginal |secretions, |breast |milk |* |not |through |tears |or |sweat

-HIV |is |higher |now |than | 2007 |

saliva |is |not |documented |

**95% |of |people |infected |will |seroconvert |within | 6 |months

( |6-12 |weeks |after |initial |infection)

Early |HIV |- |Category |I |- |correct |answer |✔CD4 |count |is |greater |than |500cells/mm

symptoms: |lymphadenopathy, |skin |lesions, |herpes |simplex |labials(oral |herpes), |hairy |leukoplakia |(hairy |tongue)

Intermediate |Stage |of |HIV |-Category |II |- |correct |answer |✔CD4 |count |200- |cells/mm

symptoms: |skin |lesions, |oral |lesions( |candidiasis-- |a |predictor |for |(PCP) |pneumocystic |carinii |pneumonia) |fever, |weight |loss, |headaches, |oral |lesions |** |leading |cause |of |death |is |PCP

Late |stage |of |HIV- |Category |III |- |correct |answer |✔CD4 |count |50-200 |cells/mm

Symptoms |include |AIDS |Indicator |Conditions: |

-opportunistic |infections- |microorganisms |are |capable |of |taking |over |a |immunocompromised |person |(wouldn't |happen |in |healthy |person) |

-Constitutional |Disease- |AKA |HIV |wasting |syndrome(fever, |weight |loss, |anemia, |weakness, |dementia, |degeneration |of |body) |

-Encephalophathy- |organic |mental |disorders |( |poor |memory, |depression, |motor |dysfunction) |

-Neoplasms |- |Kapsosi's |sarcoma, |brain |cancer, |hodgkins |lymphoma

Cytomegalovirus |- |correct |answer |✔herpesvirus |type | 5 | |cause |cytomegalic |inclusion |disease, |found |in |newborns |& |immunocompromised

  1. |Transmission: |transplanted |tissue, |bodily |fluids |(saliva, |vaginal |secretions, |semen, |breast |milk, |blood)
  2. |Symptoms: |mental |retardation, |deafness, |internal |organ |damage,high |fatality |rate

Primary |Herpetic |Gingivostomatitis |- |correct |answer |✔-first |outbreak |of |Herpes |Simplex | 1 |( |mostly |children) |

-may |present |a |multi-blister |rash |intraorally |from |the |lips |back |to |the |throat

-Very |painful |and |often |child |cannot |eat

-Takes |7-10 |days |to |clear |

  • |once |herpes |infects |body |it|lies |dormant |until |stress |causes|recurrence |and |blister |forms |( |recurrent |herpes)

Herpetic |Whitlow |- |correct |answer |✔herpes |on |the |finger |- |seen |years |ago |when |gloves |were |not |worn |( |may |be |simplex | 1 |or |2)

Creutzfeldt- |Jakob |disease |- |correct |answer |✔Known |as |CJD |or |vCJD |

-prion |disease |causing |spongiform |encephalopathies--> |pirons |are |abnormal |pathofens |that |distroy |brain |tissue |

( |belongs |to |human |and |animal |disease |* |bovine |disease) |

-rapid |dementia, |muscle |jerks

Post |exposure |plan |- |correct |answer |✔HBV-exposure | |high-titer |gammaglobulin |(HBIG |= |anti-HB |immune |serum |globulin)