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Important note for pharmacy it included GPAT Handy notes for entrance exam for degree to master in pharmacy
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000 - 950 - 1. 00 - 650 - 0. 0 - 450 - 0. 1 - 300 - 0. 2 - 250 - 0. 3 - 200 - 0. 4 - 150 - 0. 5 - 100 - 0.
(oil:water:gum) Fixed oils :- 4:2: Volatile oils:- 2:2: Mineral oils:- 3:2: Oleoresins:- 1:2:
CODE: LPSO ( apply this for tweens & spans)
for eg .. spans 20 mean sorbitan mono laurate tween 80 mean Polyoxyethylene sorbitan monooleate
L : Laurate - 20 P : Palmitate - 40 S : Stearate - 60 O : Oleate - 80
DESCRIPTIVE TERM - APPROX VOL OF SOLVENT IN ml/gm OF SOLUTE
Very soluble - less than 1 Freely soluble - 1 - 10 Soluble - 10 - 30 Sparingly soluble - 30 - 100 Slightly soluble - 100 - 1000 Very slightly soluble - 1000 - 10, Practically insoluble - more than 10,
26 - 31 poor 1.35 - 1. 32 - 37 very poor 1.46 - 1.
38 very very poor > 1.
25 - 30 - Excellent 31 - 35 - Good 36 - 40 - Fair 41 - 45 - Passable 46 - 55 - poor 56 - 65 - Very poor
66 - very very poor
Types of Glass used in Pharmaceutical Industries Parenteral Use Type I Glass: Highly Resistant Borosillicate. Used for Buffered and Unbuffered aqueous solution.
Type II Glas: Highly Resistant Sodalime glass. Buffered aqueous solution below pH 7.
Type III Glass: Moderately Resistant Sodalime glass. Used for dry powder and oily solution.
Non-Parenteral Use Type IV Glass: General Purpose Sodalime glass. Not for parenteral, for tablet,liquid oral and externals.
CRN Clinical Research Network CRO Contract Research Organisation CSM Committee on Safety of Medicines CTA Clinical Trial Authorisation (formerly the CTX, CTC, DDX) CTC Clinical Trial Certificate (Now CTA) CTC Clinical Trials Centre CTD Common Technical Document CTD Common Technical Document CTX Clinical Trial Exemption (Now CTA) DRA Drug Regulatory Affairs DUMP Disposal of Unwanted Medicines and Poisons EFPIA European Federation of Pharmaceutical Industries & Associations EMEA European Medicine Agency FDA Food & Drug Administration FIP International Pharmaceutical Federations GCP Good Clinical Practices GLP Good Laboratory Practices GMP Good Manufacturing Practices Gxp Generic term for good practice requirements in the Pharmaceutical industry HIS Indian Health Services HPLC High Performance Liquid Chromatography HRSA Health Resources & Service Administration IACUC Institutional Animal Care and Use Committee
IAES Institutional Animal Ethics Committee ICDRA International Conference for Drug Regulatory Authorities ICH International Conference on Harmonization of technical requirement for registration of pharmaceuticals IIG Inactive Ingredient Guide IMP Investigational Medicinal Products IMP - Investigational Medicinal Products IMPD Investigational Medicinal Product Dossier INDA Investigational New Drug Application INN International non-proprietary names (for pharmaceutical substances) INTDIS International Drug Information System - the previous WHO adverse reactions database IPC Indian Pharmaceutical Congress IPGA Indian Pharmacy Graduate Association ISO International Organization for Standardization ISoP International Society of Pharmacovigilance ISPE International Society for Pharmacoepidemiology MedDRA Medical Dictionary for Drug Regulatory Affairs NAFDAC National Agency for Food and Drug Administration and Control, Nigeria NCPA National Community of Pharmacist Association NCPO National Conference of Pharmaceutical Organisations NDA New Drug Application NDMS National Disaster Medical System NME New Molecule Entity
QSM-WHO Quality Assurance and Safety of Medicines (WHO) R&D Research and Development RAPS Regulatory Affairs Professionals Society RCT Randomised Clinical Trials RDE Remote Data Entry RDS Research Defence Society REC Research Ethics Committee RGN Registered General Nurse RPSGB Royal Pharmaceutical Society of Great Britain RSM Royal Society of Medicine Rx Prescription SARS Severe Acute Respiratory Syndrome SCDM Society for Clinical Data Management SIDS Sudden Infant Death Syndrome SIGAR Special Interest Group on Adverse Reactions TGA Therapeutic Goods Administration, Australia
TMF Trial Master File TUFAM General Directorate of Pharmaceuticals and Pharmacy, Turkey UDV Unit Dose Vial UKECA United Kingdom Ethics Committee Authority USP United States Pharmacopoeia WIPO World Intellectual Patent Office
For more info visit us at:- www.pharmatestseries.com
40)Vch method best suit to convert amorphous to crystalline….micronization,spray drying,any of above 41)emulsion measurement not by….electric charge,light scaterin, 42)DLVO theory… 43)microemulsion globule size… 44)beta galactosidase…SDS page…Band…2,1,,,,1,2….11….22… 45)PCR sequence 46)vch of following is not diuretic???..triamterine.indapamide,furosemide 47)Vch f followinnot active??...Allene,biphenyl.meso tartaric,None… 48)Gossypol…..not chiral,restricted rotation.. 49)Eucalyptos oil ctn…geraneol,1-8 cineole, 50)AU..Bz..Cy….ans DX 51)20student height 120,10 student height 100…Avg height ans 105 52)Sania mirza…. 53)German company take over.teva,sanofi,Pfizer.. 54)book..fatima… 55)WOF used in tretmnt of diarrohea…erythromycin,domperidone,cisapride nd one new drug 56)cycloaddition..dial alder reactn 57)thinamerin dehydrogenation produce….antracene,naphthalene… 58)synthetic Ach better than natural Ach….due to slwer hydrolysis… 59)If increase dose f salbutamol,decrease actn by…downregulation,upregulatin… 60)vch is permeable..polystrene… 61)bond energy…..
62)Tymoleptics?? 63)Max absorption from cell memb….ionizdform,unionized form… 64)WOf is not sede efeect of phenothiazine??? 65)WOFis not hepatotoxic??..rifampicin,isoniazid,ethambuto,streptomycin 66)Inhibit Aminotranferase nd 30S….tetracycline,macrolide 67)Inhibitr f 50 s ….macrlide,tetracycline 68)synonym…Graphics 69)Pictorial 70)magnaminous 71)Rebate 72)WOF is antituberculosis drug???..Ethambutol.. 73)Relience take over vch air li9ne? 74)Antinomycin D nd Rifampicin related confusin ques 76)DNA polymerase havin activity??...5 to 3,3 to 5,5 to 3 wth exonuclease, 77)SP angle… 78)sesqueterpene havin isoprene unit,,,ans 3 79)In chewable tablet vch is usd?? Mannitol… 80Manitol used bz..Ans negativ heat f soln 81)CAP hydrolyze at pH….2.1..3.3…5.4….Ph indepedant 82)Anandamide…. 83)Condensed tannin…Ans proanthocyanidin 84)Not sterilized by moist heat…taflon,polystyrene,polyethylene 85)leucopenia…decrese size of WBC,increase size f WBC
109)cardiac output/min calld……..cardiac cycle,cardiac output,force f contraction 110)most intense peak…Base peak… 111)Molar extinction coefficient Unit…. 112)Acute amoebic dysentery vch drud used..metronidazole,chloroquine.. 113)Flourouracil..ans inhibit thymidylate synthesis… 114)Folate deficiency by…methotraxate.. 115)NSAIDS induced GITproblem handled by…mesoprostol 116)Insulin ph 5..hw to make longer actin insulin lyk dt ques…increase pH,lowerpH
117)Longer actin penicillin…procain penicillin and other qption 118)WOF used as sorbent in tablet??.....MCC,silica,both,none 119)Acetylene value……ans lower than alkene 120)free radical stability…. 121)free radical str…..ans planar 122)str of twisted boat….. 123)Tartaric acid inactive bz…..internal plane f symmetry.. 124)WOF is prodrug..sulindac,sulphasalazine,aspirin 125)WOF is induced in allergy…IgE 126)WOF is participate in complement sym…IgG,IgM,IgE,IgA 127)Disinfectant fluid….ans Sch O 128)Vasaka leaf shape…ans lanceolate 129)glandular type,,,fracture…. 130)agaropectin made up f….galactose nd uronic acid,glucose nd uronic acid 131)Arhenious Eqn related ques
132)Handersn hechalbatch…pH 133)Inflamation f brain…Ans meningitis… 134)GABA..increse cl level 135)Stainin..WOF is true abt gram positive stain 136)Eculle method 4 ans volatile oil 137)Vulcanizin agent…..S,SO 138)IND full form 139)WOf is not product f dabur….meswak,glucose D,odomus 140)Colour added in vch step….syrup coatin 141)Interfacial tensn measured by..ostwald,brook field 142)vch is adultrant f saraca indica 143)tablet strength increser by ques lyk dat…..MCC,lactose 144)Mg stearate added in vch step of wet granulation…durin granulation,aftgranulation
**145)GC principle…adsorption,partition,both 146)Na salt f sachrin usd as….solublizin agent,bulkin gent,aweetnin agent
177)USP apparatus 2…ans Paddle.. 178)Streptomycin side effect….ans vestibular disturbance 179)Podophylotoxin…lignan dvt…. 180)str of ketone treated wth LiAlH
sodium polystyrene sulfonate (cationic exchange resin) 13.Iron------ deferoxamine (chelate iron) 14.Isoniazid-----pyridoxine (reverses INH induced seizures) 15.Lead-------- Ca Disodium EDTA ; BAL (dimercaprol) 16.Lithium------no effective treatment 17.Opiates-----naloxone; nalmefene 18.Organophosphates-------atro pine; pralidoxamine 19.Salicylates------activated charcoal 20.Theophylline-----charcoal; beta antagonists
Rochelle salt - sodium potassium tartarate Dakins solution - sodium hypochloride Glaubers salt - sodium sulphate Epsom salt - magnesium sulphate china clay - heavy kaolin Gypsum - calcium sulphate Calomel - mercurous chloride Soap clay - bentonite French chalk - talc Alum - potassium aluminium sulphate
