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A set of practice questions and answers related to glp-1 receptor agonists, focusing on their mechanism of action, indications, and contraindications. It is a valuable resource for students studying pharmacology, endocrinology, or related fields, offering insights into the therapeutic applications of glp-1 receptor agonists in managing obesity and type 2 diabetes.
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GLP 1 Prep Exams 2025 with Verified Answers
1. What is the primary mechanism of action of GLP-1 receptor agonists in weight loss? A, Increasing glucose absorption in the intestines B. Enhancing insulin secretion and deereasing glucagon release C. Reducing bleod pressure and cholesterol levels s fat from adipose tissue — ANS-B. Enhancing insulin secretion and deercasing glucagon release TD. Direetly removing exee Rationale: GLP-1 receptor agonists promote weight loss by increasing insulin secretion and reducing glucagon release. By modulating appetite and promoting saliely, they help decrease calorie inlake and facilitate weight loss. Which of the following is NOT an indication for GLP-1 and GIP medication use? A, Obesity with unsuccessful dict and exercise intervention B. Known hypersensitivity to GLP-1 C. Type 2 diabeles with inadequate glycemic control D. Overweight individuals with cardiovascular risk factors - ANS-B. Known hypersensitivity to GLP-1 Rationale: Known hypersensitivity to GLP-1 is a contraindication for using GLP-1 and GIP receptor agonist medications. These drugs, designed to manage obesity and Type 2 diabetes, mimic inerctin hormones to regulate glucose metabolism, However, if a patient is allergic to the medication's components, its use can result in severe E g adverse effects and must be avoided in such cases. Which population is contraindicated from using GILP—-1 and GIP medications? A, Patients with a history of pancreatitis B. Individuals over the age of 65 C. Patients with hypertension TD. Those with a BMT below - ANS-A. Patients wilh a history of pancreatilis Rationale: GLP-1 and GIP medications are typically not recommended for patients with a history of panercatitis, as they may worsen the condition, These medications have been associated with an increased risk of pancreatilis, which can be dangerous for individuals with a prior history, Additionally, individuals with a history or family history of Thyroid Medullary Cancer should avoid using these peptides. Prescribing s require carelul consideration of the patient's GI.P-1 and GIP receptor agonis medical background to ensure their safety. Those with a BMT below 25 can be prescribed this medication to assist in glycemic control if diagnosed with diabetes. Truc/False endocrine discases, including medullary thyroid carcinoma, GLP-1 and GIP medications are recommended for individuals with certain [True] [False] DANSE alse Rationale: The use of GLP—-1 and GIP medications is not recommended for individuals with certain endocrine diseases, such as medullary thyroid carcinoma, duc to the potential for serious side effects, These medications may increase the risk of thyroid