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An overview of preterm labor, including its definition, risk factors, complications, and genetic approaches for understanding its causes. Risk factors for preterm labor include twin pregnancy, pre-eclampsia, and various spontaneous factors such as infection, stress, poor nutrition, and genetic factors. Complications of preterm labor include immature lungs, brain, immune system, and digestive system. Genetic approaches to understanding preterm labor include linkage analysis, association studies, and direct resequencing of candidate genes. Several studies have identified specific genes associated with preterm labor, including those in the inflammatory cytokine pathway and the complement-coagulation pathway.
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