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Genetic Mutations Worksheet pdf, Exercises of Genetics

K12 level document on genetic mutations

Typology: Exercises

2020/2021

Uploaded on 04/20/2021

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Name________________________________ Per________
Genetic Mutation Worksheet
1.What are the types of gene mutations?
2. An error during what cellular process would create a gene mutation?
3. A geneticist found that a particular mutation had no effect on the protein coded by a gene.
What do you think is the most likely type of mutation in this gene? Why?
4. Name one amino acid that has more than one codon and one amino acid that only has one
codon.
5. Look at the following sequence: THE FAT CAT ATE THE RAT.
a. Delete the first H and regroup the letters in groups of three- write out the new groups of
three.
b. Does the sentence still make sense? ________
c. What type of mutation does this demonstrate? _____________________
d. What are the different causes of this type of mutation? ____________________________
6. You have a DNA sequence that codes for a protein and is 105 nucleotides long. A frameshift
mutation occurs at the 85th base- how many amino acids will be correct in this protein?
7. Given the following three mRNA sequences, which two code for the same protein?
#1. AGU UUA GCA ACG AGA UCA
#2. UCG CUA GCG ACC AGU UCA
#3. AGC CUC GCC ACU CGU AGU
8. What type of mutation changes a base pair without changing the amino acid?
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Name________________________________ Per________

Genetic Mutation Worksheet

1.What are the types of gene mutations?

  1. An error during what cellular process would create a gene mutation?
  2. A geneticist found that a particular mutation had no effect on the protein coded by a gene. What do you think is the most likely type of mutation in this gene? Why?
  3. Name one amino acid that has more than one codon and one amino acid that only has one codon.
  4. Look at the following sequence: THE FAT CAT ATE THE RAT. a. Delete the first H and regroup the letters in groups of three- write out the new groups of three. b. Does the sentence still make sense? ________ c. What type of mutation does this demonstrate? _____________________ d. What are the different causes of this type of mutation? ____________________________
  5. You have a DNA sequence that codes for a protein and is 105 nucleotides long. A frameshift mutation occurs at the 85th base- how many amino acids will be correct in this protein?
  6. Given the following three mRNA sequences, which two code for the same protein? #1. AGU UUA GCA ACG AGA UCA #2. UCG CUA GCG ACC AGU UCA #3. AGC CUC GCC ACU CGU AGU
  7. What type of mutation changes a base pair without changing the amino acid?
  1. Below is the base sequence for the normal protein for normal hemoglobin and the base sequence for the sickle cell hemoglobin. Normal GGG CTT CTT TTT Sickle GGG CAT CTT TTT A. Transcribe and translate the normal and sickle cell DNA. Normal mRNA Normal tRNA Amino Acid Sickle mRNA Sickle tRNA Amino Acid B. Identify this as a point or frameshift mutation and explain how you know. C. If the base sequence read GGG CTT CTT AAA instead, would this result in sickle cell hemoglobin? Explain