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Gene and Chremesome Mutation Worksheet ~frefevence pgs. 239=240-in Modern Bintogy textbooky— Name Look at the diagrams, then answer the questions, being made. Date Por, ‘iftect a single gene by changing its base sequence, resulting in an incorrect, or nonfunctional, protein @a HMESAPOTTOF muccion, occurs where one nucleotide base is replaced by another. These are often called “pel mmtationss because a single base is changed, at onc point in the gene. SOMETIMES, these base (A,T,C,G) substitutions lead to “Missense” or “Nonsense” mutations: hha! DAR code far ar amin acids CATCATOATCAT ‘Origa DNA code tor an amino acl sequence, ou EA GEASERCERGCAGER 1 i 7 oases | : ATMs Wis His 1 aie Halse Tai W sis 4 sie H gin H Gig He ae Aming acle Reglavomen: uf a ‘Amino aod Replacer-ant cia sine suclctl, sine nuslectie, “ Crt CAGGCAGCAGTAGCAGEARECAS i 7 Bin Hie Win He ‘eerrwet araine avid, wi 0 Inconvor soqeroy Gnubes ‘Vodues 3 33 Yanedoning protein, ahevtan"9g of protein. 95 Fab FUL in tao 115 as a et ..and sometimes, because there is more than one codon for each amino acid, th mutations can be SH ‘iReR OH THUR ‘Original UNA coda for an amino aci¢ sequence Saree ap So 5 avery ereroar ener ana vas Da CAT CATCATCATCATCATS bases pt i His Hs Cis Hs Hiss _itis’ Aniine acl Insertion of & ingle nualootde 14 AX “jnooreat amine atid sequence, whic may produce 2 malfunctioning preteln. 38 Mationat tee et being Celginal Dk 4 rede foram amino acid sequence. OT CASK AT OAT CAT GCATCATSATOCAYT bases dno ogi Derotian of » ‘Prglo mucteokda, CATCATCATOTCATGCATCATG : ne ac ‘ngorect aming arid Secuonte. wile: mizy produce 9 risitenstenleg psolata. sung lat at Moe 
