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The instructions and questions for the semester ii examinations in 2009/2010 for the modules reproduction, development and aging. The exam consists of 4 questions and covers topics such as fetal adaptations, sex determination, gametogenesis, endocrine roles of the testes, water soluble and lipid soluble hormones, and the eukaryotic cell cycle. Additionally, there are questions about stem cells and their potential applications.
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Candidates must answer 4 questions
Exam Code(s) 3BO2, 3BS9, 1OA Exam(s) 3 rd^ Biomedical Science, 3rd^ Undenominated Science Occasional Arts Module Code(s) SI Module(s) Reproduction, Development and Aging Paper No. 1 External Examiner(s) Prof. S. Wray Internal Examiner(s) Dr. A. Hynes, Dr L.Quinlan Instructions: (^) Answer 4 questions Duration Two hours No. of Answer books Department Course co-ordinator One Physiology Dr. M. Roche Requirements : None
Q1. In utero the fetus is exposed to a constant state of hypoxia. Describe the adaptations that occur which allow the fetus to develop under such conditions Q2. Discuss the process of sex determination in humans Q3. Describe both the gametogenic and endocrine roles of the testes. Q4. Discuss water soluble versus lipid soluble hormones/first messengers, under the following headings, general chemical nature of the molecule, transport, receptor location and 2nd messengers involved. Q5. Answer the following in relation to the eukaryotic cell cycle a. Draw a simple diagram of the cell cycle indicating the major events that occur at each stage. b. What are checkpoints and where do they occur in the cycle. c. What are cyclins and what is there role in cell cycle progression. Q6. Answer the following in relation to stem cells a. Using clear examples explain the terms Totipotent, Pluripotent, Multipotent. b. What is somatic cell nuclear transfer and what potential application does this technology have.