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Final Exam Practice - Neuroscience | BIOL 4315, Exams of Biology

Material Type: Exam; Professor: Ziburkus; Class: Neuroscience; Subject: (Biology); University: University of Houston; Term: Spring 2013;

Typology: Exams

2012/2013

Uploaded on 12/17/2013

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PEOPLESOFT NAME Date/Time Circle correct Answer
65 Questions 2 points each
1) Egyptians in 2000-3000 BC thought that the brain was the major controlling organ of the body.
a) True
b) False
2) Golgi stain can reveal detailed dendritic morphology of the neurons.
a) True
b) False
3) Multiple sclerosis is an auto-immune disorder that causes de-myelination.
a) True
b) False
4) Dendritic spine anatomy is dynamic and they can change their shape and number.
a) True
b) False
5) Ionic conductance strength and direction depend on the membrane potential value.
a) True
b) False
6) Kinases dephosphorylate ion channels.
a) True
b) False
7) At resting membrane potentials, neuronal membranes are most permeable to potassium ions.
a) True
b) False
8) Sodium equilibrium potential in neurons is approximately -50mV
a) True
b) False
9) Efferent motor neuron somas are located in the peripheral nervous system.
a) True
b) False
10) Action potential is an example of graded potential.
a) True
b) False
11) The rising phase of the neuronal action potential is due to potassium infflux.
a) True
b) False
12) Cranial nerve V (five) contains only sensory components.
a) True
b) False
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65 Questions 2 points each

  1. Egyptians in 2000-3000 BC thought that the brain was the major controlling organ of the body. a) True b) False

  2. Golgi stain can reveal detailed dendritic morphology of the neurons. a) True b) False

  3. Multiple sclerosis is an auto-immune disorder that causes de-myelination. a) True b) False

  4. Dendritic spine anatomy is dynamic and they can change their shape and number. a) True b) False

  5. Ionic conductance strength and direction depend on the membrane potential value. a) True b) False

  6. Kinases dephosphorylate ion channels. a) True b) False

  7. At resting membrane potentials, neuronal membranes are most permeable to potassium ions. a) True b) False

  8. Sodium equilibrium potential in neurons is approximately -50mV a) True b) False

  9. Efferent motor neuron somas are located in the peripheral nervous system. a) True b) False

  10. Action potential is an example of graded potential. a) True b) False

  11. The rising phase of the neuronal action potential is due to potassium infflux. a) True b) False

  12. Cranial nerve V (five) contains only sensory components. a) True b) False

65 Questions 2 points each

  1. Corpus callosum is located in the cerebellum and carries information between the two cerebellar lobes. a) True b) False

  2. Primary motor cortex is located in the parietal lobe. a) True b) False

  3. Brainstem contains pons, cerebellum, and medula. a) True b) False

  4. Complex cells have the concentric On center and Off surround receptive fields. a) True b) False

  5. The LGN on one side of the brain contains projections from contralateral nasal and ipsilateral temporal hemiretinas. a) True b) False

  6. Stapes, maleus, and incus are present in the middle ear. a) True. b) False.

  7. Hair cells in the proximal cochlea adjacent immediately to the oval window process the lowest frequency sound. a) True. b) False.

  8. Paralymphic fluid filled scala tympani contains the organ of corti. a) True. b) False.

  9. Considering the modern understanding of the brain function, which statement is incorrect?

a) Neuronal information processing is both serial and parallel. b) Neuronal information processing happens only in series. c) Each function is subserved by more than one neural pathway. d) When one neural pathway is damaged, others may compensate for this damage. e) Complex cognitive functions involve several interconnected areas of the brain.

  1. Which is not a part of neuronal cytoskeletal elements? a) Microtubules. b) Myelin.

65 Questions 2 points each

  1. Which statement is true about the AMPA channels? a) AMPA channel conductance is responsible for the early EPSP component. b) AMPA channel has a glutamate binding site. c) AMPA channel acts as a 'coincident detector'. d) At resting membrane potential, AMPA channel is closed due to Mg++ blockade. e) Two of the above.

  2. If the membrane potential is voltage clamped at -70mV, which neurotransmitter channel mediated currents will be absent? a) GABA. b) Glutamate. c) Kainate. d) All of the Above.

  3. Which represents the correct hierarchical information processing of a visual stimulus. a) Concentric/center-surround on/off cells - Complex cells - Simple cells. b) Bipolar Cells- V1 layer II-III On/Off center-surround cells - LGN cells - area V2. c) Retinoganglion cells - Photoreceptors - Lateral geniculate nucleus (LGN) - area V1. d) Photoreceptors- On/Off center-surround cells - Simple cells - Complex Cells.

  4. This is the correct hierarchical sequence of the auditory stimulus processing. (Some intermediate structures may be omitted.) a) Vesibulocochlear nerve - Inferior Colliculus - Cochlear Nuclei - Medial Geniculate nucleus - Primary Auditory cortex. b) Cranial nerve VIII - Cochlear Nuclei โ€“ Medial Geniculate nucleus - Inferior Colliculus - Primary Auditory cortex. c) Cranial nerve V - Cochlear Nuclei โ€“ Inferior Colliculus - Medial Geniculate nucleus - Primary Auditory cortex. d) Hair cells โ€“ Spiral ganglion cells โ€“ Cochlear Nuclei โ€“ Inferior Colliculus - Medial Geniculate nucleus - Primary Auditory cortex.

  5. This is the correct direction of connectivity of the hippocampal tripartite synapse. (Not all of the structures/pathways included): a) Entorhinal cortex perforant path - Cornus Ammoni (CA) area 1 - Subiculum and Entorhinal cortex. b) Entorhinal cortex perforant path - Granule cells of the Dentate Gyrus - Mossy fibers to CA3 - Schaffer collaterals to CA c) Entorhinal cortex Schaffer collateral to CA1 - Mossy fibers from CA1 to CA3 - CA3 perforant path to granule cells. d) All of the above

  6. Excitatory cells in the dentate gyrus are called: a) Granule cells. b) Interneurons. c) Motor neurons. d) Hair cells. e) Basket cells. f) Cholinergic cells.

65 Questions 2 points each

  1. Pick the correct statement about hippocampal anatomy and/or function: a) Hippocampus receives the bulk of the visual inputs from the retina. b) CA1 pyramidal cells receive bulk of its excitatory input via the Schaffer collaterals from the CA3 area. c) Hippocampus has nothing to do with the spatial navigation. d) Mossy fibers are formed by the axons leaving the entorhinal cortex and entering into the subiculum.

  2. Dermatomes are: a) Areas of the skin innervated by left and right dorsal root ganglion of the single spinal segment. b) Areas of the skin innervated by left and right dorsal root ganglion from three spinal segments. c) Located inside the spinal cord. d) Herpes virus can reappear in a single dermatome as shingles. e) Two of the above f) None of the above

  3. NMDA receptors are co-incident detectors because they can: a) Co-incidentally detect the binding of GABA and release of the magnesium block. b) Co-incidentally detect the binding of glutamate and GABA. c) Co-incidentally detect the binding of glutamate and membrane depolarization. d) None of the above.

  4. Which is a correct description of the rate code. a) Rate code prioritizes the importance of action potential firing frequency rather than the precise order of pre-synaptic and post-synaptic activation. b) Only high frequency rate code causes LTP and LTD. c) For rate code, the order of pre-synaptic and post-synapti activation is the most important factor in causing long term plasticity. d) Two of the above.

  5. What is the most appropriate description of the phantom limb syndrome: a) Seeing numbers as colors. b) Neglecting half of the body's somatic sensations. c) It can be explained by a 'discontinuous' map of the somatosensory homunculus. d) It is caused by acetylcholinesterase inhibitors. d) None of the above.

  6. Developmentally regulated retinogeniculate axon segregation is: a) A non-competitive process. b) The same in adults as it is in newborn rodents. c) A competitive Hebbian-like plasticity process. d) None of the above.

  7. After the stimulation of Schaffer collaterals, extracellular recording electrode placed below the soma of the CA1 pyramidal cells will record a population spike and not a field potential (fEPSP). a) True. b) False.

65 Questions 2 points each

  1. Pick the correct association for the above graphs.

    a) A-sodium current reversal. b) A- EPSP reversal. c) A -IPSP reversal. d) B- potassium current reversal. e) B-GABA reversal. f) B-IPSP reversal.

65 Questions 2 points each

  1. Choose the correct answer based on these graphs. In this Ohmic (linear) setting, which might be (the closest to resemble) the IV plot for a potassium channel? a) A b) B c) C

65 Questions 2 points each

  1. The top graph illustrates that a depolarizing current was injected into a cell. In the bottom graph, pick the inward transient sodium current curve marked by the appropriate letter and arrow. a) A b) B

65 Questions 2 points each

  1. Which one of these symbols stands for a capacitor? a) A b) B c) C

65 Questions 2 points each

  1. This question pertains to the sensory fiber classes and their processing functions. Pick the best match. a) A - temperature. b) B - proprioception c) C - proprioception d) D - pain

65 Questions 2 points each

  1. In the IV plot above, which curve represents the late EPSP component in the normal solution without any blockers? a) Closed circles. b) Open circles. c) Closed triangles. d) Open triangles.

65 Questions 2 points each

  1. These are the optic nerve axons. Pick a letter indicating the correct anatomical structure. a) A b) B c) C d) D e) E f) F

65 Questions 2 points each

  1. This letter and arrow indicate location of the pons. a) A b) B c) C d) D e) E f) F g) G h) H i) I j) J

65 Questions 2 points each

  1. This letter and arrow indicate medulla oblongata. a) A b) B c) C d) D e) E f) F g) G h) H

65 Questions 2 points each

  1. Which letter and arrow indicate the correct location of the damage in the visual pathways? Area of the visual field shown in black represents the area of visual deficit. a) A b) B c) C d) D