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Comprehensive Guide to Liver and Brain Disorders: Assessment, Interventions, and Treatment, Exams of Health sciences

A comprehensive overview of various liver and brain disorders, including stroke, traumatic brain injury, increased intracranial pressure, brain tumors, hepatitis, cirrhosis, liver damage, liver transplant, hemochromatosis, and portal hypertension. It covers key aspects such as assessment, interventions, treatments, common medications, and interdisciplinary care planning. Particularly useful for students in healthcare fields, providing a detailed guide to understanding and managing these conditions.

Typology: Exams

2024/2025

Available from 02/11/2025

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Final Exam Content Guide,Latest.
1. Stroke CVA Brain attack disruption of cerebral blood flow secondary to ischemia, hemorrhage, brain
attack, or embolism
1) Hemorrhagic ruptured artery or aneurysm = ischemia and ↑ICP caused by expanding collection
of blood. Prognosis poor.
2) Thrombotic d/t development of blood clot on an atherosclerotic plaque in a cerebral artery.
The clot gradually shuts off the artery causing ischemia distal to the occlusion. Symptoms evolve
over several hours to days.
3) Embolic – d/t embolus traveling from another part of the body to the cerebral artery. Blood to brain
distal to occlusion immediately shuts off causing neuro deficits, or a loss of consciousness can
instantly occur. --- This type of stroke may be reversed with rtPA if given within 4.5hrs of initial
symptoms.
Risk Factors: HTN, DM, smoking == PREVENTION == Early treatment of HTN, maintain BGL, quit smoking.
Right vs Left: Right = visual and spatial awareness and propriception. Left = language, math, and analytic
thinking (agnosia – inability to recognize familiar objects).
Interventions: Have suction equipment avail. Vitals 1-2hrs – Notify MD if BP >180/110. Temp (↑ can
cause ↑ICP). O2 and maintain > 92%. Cardiac monitor. Monitor LOC (↑ICP). Elevate HOB >30 to
reduce ICP and promote venous drainage. Maintain midline neutral position. SEIZURE
Percautions. Assist with communication. Assist with safe feeding. Intervene for complications r/t
immobility. Active ROM to unaffected exteemities, and Passive ROM to affected extremities. Vision
deficits = instruct scanning techinique (turning head). Prevent DVT. Assist with ADL’s. Provide
frequent rest.
Complitcations: – Prevent shoulder subluxation if affected arm is not supported. Unilateral neglect (nurse to
provide arm sling/foot rest). Dysphagia and aspiration (nurse assess gag reflex, monitor swallowing).
MEDS: Anticoagulant: Enoxaparin (Lovenox), warfarin (Coumadin) – Antiplatelet: Aspirin – Thrombolytic: rtPA –
Antiepileptic: phenytoin (Dilantin), gabapentin (Neurontin)
2. Traumatic brain injury – major causes, eligibility for federal programs, types, assessment,
interventions, rehabilitation, support, interdisciplinary care planning, sympathetic storming prevention
3. Mild brain injury – common types, assessment, interventions, patient education, prevention
4. Moderate brain injury – common types, assessment, interventions, treatments, interdisciplinary care
planning, patient education, prevention
5. Increased intracranial pressure – assessment, interventions, unsafe interventions, treatments,
monitoring, common medications, what to avoid, interdisciplinary care planning, patient education
Treatment: Cooling blankets to lower overall body temperature. By lowering temperature of the body, the
metabolic rate in the brain decreases, thus reducing metabolic demands and allowing the brain to begin to
recover; Sedative or neuromuscular medications may be needed to prevent shivering and anxiety, which will
increase temperature; ICP is measured by placing a small tube in the ventricles of the brain
(ventriculostomy) Nursing Interventions:
Monitor the cerebral perfusion pressure, difference between the CPP is the difference between the ICP
and the mean arterial pressure (MAP)
CPP is calculated by subtracting the ICP from the MAP
Keep oxygen saturation at 100%
Help with environmental stimuli; keep lights and noise low
Visitors limited to one to two for short time
Institute measures to promote healing and prevent complications; turn every 2 hours & HOB at 30
Compression stockings
Anticoagulant therapy
6. Brain tumor- Cancer usually originates in the lung and breast but can also start in the kidney, prostate, or
as lymphoma or melanoma, which then spreads to the brain
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Final Exam Content Guide,Latest.

  1. StrokeCVA – Brain attack disruption of cerebral blood flow secondary to ischemia, hemorrhage, brain attack, or embolism 1) Hemorrhagic – ruptured artery or aneurysm = ischemia and ↑ICP caused by expanding collection of blood. Prognosis poor. 2) Thrombotic – d/t development of blood clot on an atherosclerotic plaque in a cerebral artery. The clot gradually shuts off the artery causing ischemia distal to the occlusion. Symptoms evolve over several hours to days. 3) Embolic – d/t embolus traveling from another part of the body to the cerebral artery. Blood to brain distal to occlusion immediately shuts off causing neuro deficits, or a loss of consciousness can instantly occur. --- This type of stroke may be reversed with rtPA if given within 4.5hrs of initial symptoms. Risk Factors : HTN, DM, smoking == PREVENTION == Early treatment of HTN, maintain BGL, quit smoking. Right vs Left: Right = visual and spatial awareness and propriception. Left = language, math, and analytic thinking (agnosia – inability to recognize familiar objects). Interventions : Have suction equipment avail. Vitals 1-2hrs – Notify MD if BP >180/110. Temp (↑ can cause ↑ICP). O2 and maintain > 92%. Cardiac monitor. Monitor LOC (↑ICP). Elevate HOB >30 to reduce ICP and promote venous drainage. Maintain midline neutral position. SEIZURE Percautions. Assist with communication. Assist with safe feeding. Intervene for complications r/t immobility. Active ROM to unaffected exteemities, and Passive ROM to affected extremities. Vision deficits = instruct scanning techinique (turning head). Prevent DVT. Assist with ADL’s. Provide frequent rest. Complitcations: – Prevent shoulder subluxation if affected arm is not supported. Unilateral neglect (nurse to provide arm sling/foot rest). Dysphagia and aspiration (nurse assess gag reflex, monitor swallowing). MEDS : Anticoagulant: Enoxaparin (Lovenox), warfarin (Coumadin) – Antiplatelet: Aspirin – Thrombolytic: rtPA – Antiepileptic: phenytoin (Dilantin), gabapentin (Neurontin)
  2. Traumatic brain injury – major causes, eligibility for federal programs, types, assessment, interventions, rehabilitation, support, interdisciplinary care planning, sympathetic storming prevention
  3. Mild brain injury – common types, assessment, interventions, patient education, prevention
  4. Moderate brain injury – common types, assessment, interventions, treatments, interdisciplinary care planning, patient education, prevention
  5. Increased intracranial pressure – assessment, interventions, unsafe interventions, treatments, monitoring, common medications, what to avoid, interdisciplinary care planning, patient education Treatment: Cooling blankets to lower overall body temperature. By lowering temperature of the body, the metabolic rate in the brain decreases, thus reducing metabolic demands and allowing the brain to begin to recover; Sedative or neuromuscular medications may be needed to prevent shivering and anxiety, which will increase temperature; ICP is measured by placing a small tube in the ventricles of the brain (ventriculostomy) Nursing Interventions: - Monitor the cerebral perfusion pressure, difference between the CPP is the difference between the ICP and the mean arterial pressure (MAP) - CPP is calculated by subtracting the ICP from the MAP - Keep oxygen saturation at 100% - Help with environmental stimuli; keep lights and noise low - Visitors limited to one to two for short time - Institute measures to promote healing and prevent complications; turn every 2 hours & HOB at 30 - Compression stockings - Anticoagulant therapy
  6. Brain tumor - Cancer usually originates in the lung and breast but can also start in the kidney, prostate, or as lymphoma or melanoma, which then spreads to the brain
  • Primary brain tumor means that the cancer originated in the brain tissue; however, this type of tumor is rare
  • Secondary brain tumor is one that started in another location in the body and spread to the brain or CNS
    • Treatment: Main interventions are chemotherapy, radiation, & surgery
    • Potential Complications: Increased intracranial pressure
  1. Hepatitis – is inflammation of the liver. Increased inflammation = necrosis interfereing with blood flow to liver. Symptoms – influenza like (Fatigue, joint pain, abd pain, ↓appetite with nausea). Dark urine. Clay stool. Jaundice. Fever. Vomiting. Labs – Elevated ALT/AST and total bilirubin NORMAL VALUES : ALT or SGPT: 10-25 units/L -- 200-400 can = hepatitis or liver damage from drugs/chemicals Jaundice caused by liver = >300 not caused by liver < AST or SGOT: 8-38 units/L Liver injury can ↑by 10X. Bilirubin: Total: 0.1-1.2 mg/dL adults Liver Biopsy – most definitive diagnostic approach. Need informed consent. Have Pt lie supine URQ exposed, take EXHALE breath and hold during needle insertion – resume breathing after needle withdrawn. After procedure lie in on Right side and maintain for several hours. a. Who is at risk for : i. Hepatitis A: Individuals living with infected people, sex partners of infected people, traveling to other countries - Fecal/oral route, contaminated food or water (PPE for incontinent PT’s) - Can take vaccine after exposure. ii. Hepatitis B: Health care workers or people exposed to blood and body fluids, inmates in prisons, drug users, multiple sex partners, hemodialysis patients, recipients of clotting factor concentrates - Blood, Body fluids (semen, saliva, vaginal), blood through skin and mucous membranes - Use PPE if exposure to blood. iii. Hepatitis C: IV drug users, recipients of blood products or tissue transplants before 1992, tattoos and piercings - Blood and plasma through skin and mucous membranes - Use PPE if exposure to blood. iv. Hepatitis D: coinfection with hep B b. Chronic Hepatits = B, C, or D.
  2. Cirrhosis – Cirrhosis of the liver is a chronic, progressive condition characterized by destruction of the liver cells and subsequent formation of fibrotic tissue that reconfigures normal, healthy liver tissue. This lack of elasticity causes blood, bile, and lymphatic systems to become congested and obstructed, and further damage is incurred. ■ Extensive scarring of the liver caused by necrotic injury or chronic reaction to inflammation over time.

o Liver enzymes can be elevated with conditions such as diabetes, obesity, autoimmune disorders, some viral infections (especially hepatitis), and some genetic diseases. o Prothrombin and hemoglobin prior to liver biopsy

  1. Portal Hypertension -Assessment of, symptoms of, common diagnostic tests, lab values associated with, common medications, interdisciplinary care planning PH - Is the constant pressure of the blood, bile, and lymphatics within the liver. TREATMENT
  • Shunts to relieve the pressure in the portal vein
  • Shunts diverted blood from the portal vein to the inferior vena cava, thus bypassing the fibrotic blockage that caused congestion in the liver. distal splenorenal shunt (DSRS)
  • Transjugular intrahepatic portosystemic shunt (TIPS)
  1. Macrovesicular fatty liver – Assessment of, common causes of, risk factors, treatment, diagnostic tests, lab values, patient education, interdisciplinary care planning
  2. Musculoskeletal injuries – common types, assessment of, treatment for, common symptoms, activity and work related injuries, patient education, common medication
  3. CastingWhat risks are associated with applying a cast for a fracture? a. For unstable fractures casts may not be adequate in maintaining bone alignment. Complications of not maintaining proper alignment include nonunion, delayed union, or displacement of the fracture

segments. Casts also immobilize the muscles and joints next to the fracture site, and may cause neurovascular compromise, malunion, skin breakdown, and compartment syndrome

  1. Meniscal injury – Assessment, symptoms, interventions, diagnostic testing, medications, patient education
  2. RICE – What does it mean, when is it used, what does it treat, patient education When educating a patient with a sprain, what exactly should be taught about RICE therapy? a. The immediate goal of treatment are to prevent swelling and to maintain ROM, immediate interventions include Rest, Ice, Compression and Elevation RICE
  3. Stress Fractures – Prevention, causes, assessment, treatment, patient education
  4. Hip Replacement – Reasons for, types, complications of, monitoring, signs of infection, signs of issues with the replacement, common pain management medications, interdisciplinary care planning
  5. Decompensated congestive heart failure – signs and symptoms of, assessment of, common medications, interdisciplinary care planning, patient education, diagnostic tests, lab values
  6. Adventitious lung sounds – Assessment, causes of, treatment
  7. IV fluids – different types, why they are used and when are each type contraindicated, what to monitor for.
  8. Serum sodium concentration – Normal and abnormal values, what to monitor for, symptoms associated with abnormal values, treatment, patient education
  9. Potassium – Normal and abnormal values, what to monitor for, symptoms associated with abnormal values, treatment, patient education
  10. Acid-base imbalance – Assessment of, causes of, different types, lab values associated with, diagnostic tests, treatment, risks associated with, patient education
  11. COPD – Assessment, symptoms, causes, treatment, common medication, risks associated with, common lab values
  12. Colon Cancer – Risk factors, assessment, treatment, symptoms of, common treatment, patient education, diagnostic tests

f. Take blood pressure g. Assess level of consciousness and pupillary response, weakness or paralysis of extremities Treatment for anthrax RED: Priority I or emergent care is needed for victims who need immediate treatment, such as those with cardiac or respiratory distress, trauma and bleeding, or neurological deficits YELLOW: Priority II or urgent care is needed for victims who need treatment within 2 hours, such as clients with simple fractures, lacerations, or fevers; these victims should be reevaluated every 30 to 60 minutes GREEN: Priority III or non-urgent care is needed for victims who need treatment that can wait for hours; those with sprains, rashes, and minor pain should be reevaluated every 1-2 hrs. ORANGE tag indicates a client who has a non-emergent psychiatric condition BLACK: Victims who are deceased should be labeled with a black tag and transported to designated temporary morgue

  1. Burns – Phases, different types, phases, monitoring and treatment associated with each type and phase, interventions, interdisciplinary care planning, patient education, medication management
  2. Chest trauma – assessment, clinical manifestations, medication management, diagnostic tests, interventions, lab values
  3. Mechanical ventilation – How to communicate with a client who is, complications of, what to monitor, patient education, why and when is it used
  4. Sinus bradycardia – Assessment, symptoms, causes, interventions, treatment, common medication management, patient education 44. ECG tracings
  1. Shock – The shock syndrome, or acute circulatory failure, can be classified according to etiology into three basic categories: hypovolemic, cardiogenic, and distributive. Sub-categories of distributive shock include neurogenic, anaphylactic, and septic.

Refractory - - Death is inevitable. Failure of compensating mechanisms. No response to treatment. Risk of cardiac arrest. A rising serum lactate is an indicator of inadequate tissue perfusion due to metabolic acidosis. Low arterial oxygen content, chest pain, cardiac dysrhythmias, altered LOC, ↓urinary output. MAPB cannot be maintained without assistance. ASSESSMENT AND CARE OF SHOCK SYNDROME Clinical findings correlated with organs compromised by inadequate oxygen. Regardless of the type of shock, it leads to a SBP of less than 90 mm Hg and the narrowing of pulse pressure that is inadequate to meet the tissue needs. (SBP may be elevated initially.) Myocardial infarction – Coronary artery blood flow is blocked by atherosclerotic narrowing, thrombus formation, or (less frequently) persistent vasospasm; myocardium supplied by arteries is deprived of O2; persistent ischemia may rapidly lead to tissue death" Main cause is coronary artery disease (CAD), buildup of atherosclerotic plaque in coronary arteries that restricts blood flow to heart a. Nonmodifiable risk factors include age, gender, family history, and ethnic background b. Modifiable risk factors include smoking, obesity, stress, elevated cholesterol, diabetes mellitus, and hypertension ECG (12-lead): ST elevation, accompanied by T-wave inversion in leads that monitor affected area of heart; these changes resolve as treatment progresses Lab findings : elevated troponins (early or late diagnosis); elevated CK-MB isoenzymes over 5% (early diagnosis); or elevated LDH with “flipped” isoenzymes (late diagnosis)" Signs and Symptoms: N/V or just nausea, Diaphoresis and dizziness, chest pain lasting more than 15min (squeezing or pressure) and may extend to shoulder, left arm, back or jaw, anxiety and feelings of doom Women: fatigue, sleep disturbance, shortness of breath, back pain, upper abdominal pain, epigastric pain, and nausea with or without vomiting are the most commonly identified atypical symptoms seen in women suffering from an AMI. INTERVENTIONS :

  1. Assess pain freq; pain is usually first presenting sign of new or extended MI
  2. Hemodynamic status: BP,HR, LOC, skin color, temp. (Q5min during pain, Q15min post pain, and every 1- 2hrs post MI for 24hrs)
  3. ER treatment = MONA = Morphine (Relieve chest pain), oxygen (↑Oxygenation), nitrates (vasodilate coronary blood vessels and ↑ blood supply), and aspirin (antiplatelet agent to interfere with thrombus formation in affected artery).
  4. Monitor continuous ECG to detect dysrhythmias (PVC’s and tachy common) With new pain or changes in level or character of pain 12-lead ECG immediately.
  5. Monitor resp, breath sounds, admin O2 (2-4L/min) to ↑O2 to heart.
  6. Provide rest to ↓O2 demand to heart
  7. Angina : Angina is defined as acute cardiac pain caused by inadequate oxygen reaching the myocardium. Chest pain resulting from this restricted blood flow; (Women, diabetics, and elderly patients may not present with typical angina pain) a. Stable - a predictable response to increased activity. Ischemic episodes are precipitated by factors that increase oxygen demand (exercise) or reduce oxygen supply (anemia). Chest pain occurs predictably with the same onset, duration, and intensity and is relieved when the precipitating factor is removed or with nitroglycerin administration. b. Unstable - with unpredictability (at rest) and increasing severity – Often precursor to MI. Combo of unstable and MI = acute coronary syndrome (ACS). This syndrome is the result of rupture of an unstable or vulnerable plaque. Rupture of the plaque results in platelet aggregation and thrombus. c. Prinzmetal - caused by arterial spasm often awaking client from sleep. Underlying coronary artery stenosis may be absent. Ischemia occurs because of transient focal decreased oxygen supply unrelated to oxygen demand. Five assessment components (PQRST): factors that precipitate the symptoms, quality, radiating, severity/location, Time/duration, and factors that relieve the symptoms.

Angina pain quality is typically described as pressure, heavy, squeezing, constrictive, suffocating, vise-like, or “like an elephant sitting on my chest.” Angina is rarely described as pain. Episodes may vary from mild to severe. Several symptoms may accompany angina pain including nausea, diaphoresis, SOB, fatigue, dizziness, weakness, and anxiety. Anginal pain is not stabbing or sharp and does not change with respirations, position change, or pressure applied to the chest wall. To demonstrate anginal pain, the patient may place a clenched fist over the sternum. This is referred to as the Levine’s sign, the universal sign for angina.

  1. Vasopressin (DDAVP) – What it is used for, when is it ordered, what to monitor, patient education
  2. Kidney failures – Different types, risk factors, assessment, treatment, monitoring, patient education
  3. Compartment syndrome –Swelling in the soft tissues and muscles = compromised circulation to that area
  4. Pathological fractures – Diseases associated with, monitoring of, patient education
  5. Fractured pelvis – complications of, monitoring, patient education
  6. Blood Gas Values – Normal and abnormal lab values, signs and symptoms associated with abnormal values causes of abnormalities, treatment of, complications of abnormal values. Normal Arterial Blood Gases: Serum Ph.: 7.35-7. PaCO2 – Carbon Dioxide: 35- 45 HCO3 – Bicarbonate: 22- PaO2 – Oxygen: 80- 53. Define: a. Ascites: The accumulation of fluid in the peritoneal cavity. b. Cholangitis: Inflammation of the bile duct c. Cholecystitis: Inflammation of the gallbladder. d. Cholelithiasis: Gallstones. e. Cholestasis: Any condition that impedes bile flowing freely through the bile ducts. f. Gluconeogenesis: The process of the liver converting predominant amino acids to glucose in the fasting state g. Glycogen hydrolysis: Conversion of stored glycogen into usable glucose to meet the immediate energy needs of the body. h. Glycogen synthesis: Conversion of glucose to glycogen that can be stored in preparation of times of fasting i. Gynecomastia: Breast enlargement in men j. Hepatomegaly: Enlarged liver, palpated below the level of the ribs. k. Icterus: Yellow coloration in the sclera of the eye l. Jaundice: Yellow pigmentation of the skin and sclera. m. Laparoscopic cholecystectomy: A surgical procedure using a laparoscope to remove the gallbladder n. Liver lobule: The functional unit of the liver o. Refractory ascites: Ascites that cannot be effectively managed with normal therapies. p. Steatorrhea: Pale-yellow, greasy, fatty stool, or chronic watery diarrhea Musculoskeletal Trauma Define: o Ankle sprain: When the ankle is displaced or a sudden force is applied, the ligaments are stretched beyond their normal stretching capacity and a sprain of the ligament occurs.

EXAM QUESTIONS

  1. A client with a new burn injury asks the nurse why he is receiving intravenous cimetidine (Tagamet). What is the nurse’s best response?------“This will help prevent stomach ulcers, which are common after burns.”
  2. The nurse is assigned a group of patients. Which patient would the nurse identify as being at increased risk for impaired gas exchange? A patient with a hemoglobin of 8.5 g/dL
  3. The nurse is assessing a patient for the adequacy of ventilation. What assessment findings would indicate the patient has good ventilation? (Select all that apply.) ---- 1. Oxygen saturation level is 98%. 2. Nail beds are pink with good capillary refill. 3. There is presence of quiet, effortless breath sounds at lung base bilaterally.
  4. The nurse is assessing a patient's differential white blood cell count. What implications would this test have on evaluating the adequacy of a patient's gas exchange? Elevation of WC = generalized inflammation WRONG : A. White cell count will differentiate types of respiratory bacteria.
  5. The nurse would identify which patient as having a problem of impaired gas exchange secondary to a perfusion problem? A patient with- Peripheral artery disease of LE WRONG : severe anemia secondary to chemotherapy
  6. A client is in the emergency department after being rescued from a house fire. After the initial assessment, the client develops a loud, brassy cough. What intervention by the nurse takes priority?---Apply oxygen and continuous pulse oximetry.
  7. The nurse would identify which body systems as directly involved in the process of normal gas exchange? (Select all that apply.) Cardiovascular system, Pulmonary system, Neurologic.
  8. The RN has assigned a client who has an open burn wound to the LPN. Which instruction is most important for the RN to provide the LPN? Wash hands on entering the client’s room.
  9. The acid-base status of a patient is dependent on normal gas exchange. Which patient would the nurse identify as having an increased risk for the development of respiratory acidosis? A patient with ---- Chronic lung disease with ↑CO2 retention WRONG--- - acute anxiety, hyperventilation, and decreased carbon dioxide retention
  10. A client who weighs 90 kg and had a 50% burn injury at 10 AM arrives at the hospital at noon. Using the Parkland formula, calculate the rate that the nurse should use to deliver fluid when the IV is started at noon. ---- 4ml/Kg/%TBSA per 24 hours ---- 4 X 90 = 360 X 50 = 18,000 ---- Give half in first 8 hours 9,000/8 and second half in 16 hours 9,000/16. HOWEVER!!!!  (Burn at 10am and its noon, so 6 hour infusion needed) 9,000 / 6 = 1,500mL/hr