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Bio 375 Practice Exam 1 with Questions and Answers, Exams of Pathophysiology

A practice exam for bio 375 with 25 questions and answers related to malignant tumors, immune response, inflammatory response, genetics, and congenital defects. It covers various topics such as chromosomal disorders, benign and malignant tumors, iatrogenic diseases, and systemic signs of disease.

Typology: Exams

Pre 2010

Uploaded on 08/08/2009

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Bio 375 Practice Exam 1
1. One reason for staging a malignant tumor at the time of diagnosis is
to:
A. identify the original cell from which the tumor developed
B. locate and identify the primary tumor
C. decide the initiating factor for a particular tumor
D. determine the best treatment and the prognosis
T F 2. Incomplete penetrance occurs when dominant genes seem to skip
generations in a pedigree.
3. Which cells are required to process and present antigens from foreign
material as the initial step in the immune response?
A. T–helper cells
B. macrophages
C. eosinophils
D. monocytes
4. A large burn area predisposes to decreased blood pressure because:
A. bleeding occurs under the burn surface
B. the heart is damaged by toxic materials
C. fluid and protein shift out of the vascular compartment
D. vasoconstriction occurs in the burn area
5. Replacement of damaged tissue by similar cells is termed:
A. fibrosis
B. regeneration
C. resolution
D. repair by scar tissue
6. What is the correct order of the following events in the inflammatory
response immediately after tissue injury?
1. increased permeability of blood vessels
2. dilation of blood vessels
3. transient vasoconstriction
4. migration of leukocytes to the area
5. hyperemia
A. 5, 3, 2, 1, 4
B. 1, 2, 4, 5, 3
C. 2, 3, 5, 4, 1
D. 3, 2, 5, 1, 4
7. Which statement applies to contact dermatitis?
A. it occurs when IgE antibodies on the skin react with the causative
substance
B. it may result from ingested foods
C. the urticaria (hives) gradually spreads over the body
D. a type IV reaction occurs in areas of direct contact with the
causative substance
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Bio 375 Practice Exam 1

  1. (^) One reason for staging a malignant tumor at the time of diagnosis is to:

A. (^) identify the original cell from which the tumor developed B. (^) locate and identify the primary tumor C. (^) decide the initiating factor for a particular tumor D. (^) determine the best treatment and the prognosis

T F 2. (^) Incomplete penetrance occurs when dominant genes seem to skip

generations in a pedigree.

  1. (^) Which cells are required to process and present antigens from foreign material as the initial step in the immune response?

A. (^) T–helper cells B. (^) macrophages C. (^) eosinophils D. (^) monocytes

  1. (^) A large burn area predisposes to decreased blood pressure because:

A. (^) bleeding occurs under the burn surface B. (^) the heart is damaged by toxic materials C. (^) fluid and protein shift out of the vascular compartment D. (^) vasoconstriction occurs in the burn area

  1. (^) Replacement of damaged tissue by similar cells is termed:

A. (^) fibrosis B. (^) regeneration C. (^) resolution D. (^) repair by scar tissue

  1. (^) What is the correct order of the following events in the inflammatory response immediately after tissue injury?
    1. increased permeability of blood vessels
    2. dilation of blood vessels
    3. transient vasoconstriction
    4. migration of leukocytes to the area
    5. hyperemia

A. (^) 5, 3, 2, 1, 4 B. (^) 1, 2, 4, 5, 3 C. (^) 2, 3, 5, 4, 1 D. (^) 3, 2, 5, 1, 4

  1. (^) Which statement applies to contact dermatitis?

A. (^) it occurs when IgE antibodies on the skin react with the causative substance B. (^) it may result from ingested foods C. (^) the urticaria (hives) gradually spreads over the body D. (^) a type IV reaction occurs in areas of direct contact with the causative substance

  1. (^) Which of the following would be the most likely cause of an iatrogenic disease?

A. (^) an inherited disorder B. (^) a combination of specific etiologic factors C. (^) an unwanted effect of a prescribed drug D. (^) prolonged exposure to toxic chemicals in the environment

  1. (^) Which of the following is a characteristic of a benign tumor?

A. (^) unencapsulated, invasive B. (^) it consists of undifferentiated cells C. (^) it exerts systemic effects D. (^) cells appear relatively normal

  1. (^) A warning sign of possible cancer would be any of the following except:

A. (^) persistent, unusual bleeding B. (^) a change in bowel habits C. (^) sudden development of fever, nausea, and diarrhea D. (^) a change in shape, color, or surface of a skin lesion

  1. (^) A tissue in which the cells vary in size and shape and show increased mitotic figures would be called:

A. (^) metaplasia B. (^) atrophy C. (^) dysplasia D. (^) hypertrophy

  1. (^) Hypertrophy of the heart would be related to:

A. (^) an increase in the size of the individual cells B. (^) an increase in the number of cells in an area C. (^) replacement of normal cells by a different type of cell D. (^) a decrease in the size of the individual cells

T F 13. (^) Chromosomal defects usually result from an error during meiosis.

  1. (^) Down's syndrome is an example of a(n):

A. (^) autosomal dominant disorder B. (^) multifactorial disorder C. (^) developmental defect D. (^) chromosomal disorder

  1. (^) Grading of newly diagnosed malignant tumors is based on the:

A. (^) size of the tumor B. (^) number of metastases C. (^) degree of differentiation of the cells D. (^) number of lymph nodes involved

  1. (^) Teratogens have the most serious effects on fetal development during

the:

A. (^) period of fertilization B. (^) first six months of pregnancy C. (^) period of organogenesis D. (^) final three months of pregnancy

  1. (^) Tears are considered to be part of the:
    1. first line of defense
    2. second line of defense
    3. third line of defense
    4. specific defenses
    5. nonspecific defenses

A. (^) 1, 4 B. (^) 1, 5 C. (^) 3, 4 D. (^) 2, 5

  1. (^) When an allergen binds with IgE antibodies on mast cells, resulting in

release of chemical mediators, this reaction is called:

A. (^) cytotoxic hypersensitivity B. (^) immune complex hypersensitivity C. (^) type I hypersensitivity D. (^) type IV hypersensitivity