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Exam 3 with Answers - Microbiology for Health Science | BIOL 2250, Exams of Biology

Clayton State UniversityBiology
Prof. Renee E. Mcfarlane

Material Type: Exam; Professor: McFarlane; Class: Microbiology for Health Sci.; Subject: Biology; University: Clayton State University; Term: Fall 2008;

Typology: Exams

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BIOL 2250 – Microbiology for Health Sciences – Exam 3 Fall 2008
Instructor: Renee McFarlane
NAME _________________________________________
Mark your answers on BOTH the scantron sheet and on the test.
Write your name on the first page of the test and on the scantron answer sheet. If there is not an answer marked
on the test, then you will not receive credit for mistakes due to erasure.
The test is worth 100 points. The multiple-choice will be worth 80 points and the true/false questions are worth
a total of 20 points.
Please report any typos or numbering errors.
Finally, if a question is not clear, ASK for clarification. If you are confused about how to mark the
answers on your scantron sheet ASK! Credit will not be given for unasked questions.
1.The most frequently used portal of entry for
pathogens is the
a. mucous membranes of the respiratory
tract.
b. mucous membranes of the
gastrointestinal tract.
c. skin.
d. parenteral route.
e. All are used equally.
2.Which of the following is not a characteristic of
inflammation?
a. Red color from blood accumulation
b. Pain from injury to local nerves
c. Abnormally high body temperature
d. Swelling from accumulation of fluid
3.Which of the following is not a membrane-
disrupting toxin?
a. A-B toxin
b. Hemolysin
c. Leukocidins
d. Streptolysin O
e. Streptolysin S
4. Large complex molecules that provoke an
immune response are referred to as:
a. phagocytes
b. antigens
c. transfer factors
d. lymphokines
5. The ID50 is a
a. measure of pathogenicity.
b. dose that will cause an infection in
50% of the test population.
c. dose that will kill some of the test
population.
d. dose that will cause an infection in some
of the test population.
e. dose that will kill 50% of the test
population.
6. Which type of antibody protects the respiratory
and infant gastrointestinal tracts?
a. IgA
b. IgE
c. IgG
d. IgM
7. All of the following may be used for adherence
except
a. fimbriae.
b. cell membrane mannose.
c. glycoproteins.
d. lipoproteins.
e. capsules.
8. The main cells participating in antibody-mediated
immunity are:
a. phagocytes
b. cytotoxic T cells
c. macrophages
d. B cells
1
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Instructor: Renee McFarlane

NAME _________________________________________

Mark your answers on BOTH the scantron sheet and on the test.

Write your name on the first page of the test and on the scantron answer sheet. If there is not an answer marked

on the test, then you will not receive credit for mistakes due to erasure.

The test is worth 100 points. The multiple-choice will be worth 80 points and the true/false questions are worth

a total of 20 points.

Please report any typos or numbering errors.

Finally, if a question is not clear, ASK for clarification. If you are confused about how to mark the

answers on your scantron sheet ASK! Credit will not be given for unasked questions.

1.The most frequently used portal of entry for pathogens is the a. mucous membranes of the respiratory tract. b. mucous membranes of the gastrointestinal tract. c. skin. d. parenteral route. e. All are used equally. 2.Which of the following is not a characteristic of inflammation? a. Red color from blood accumulation b. Pain from injury to local nerves c. Abnormally high body temperature d. Swelling from accumulation of fluid 3.Which of the following is not a membrane- disrupting toxin? a. A-B toxin b. Hemolysin c. Leukocidins d. Streptolysin O e. Streptolysin S

  1. Large complex molecules that provoke an immune response are referred to as: a. phagocytes b. antigens c. transfer factors d. lymphokines 5. The ID 50 is a a. measure of pathogenicity. b. dose that will cause an infection in 50% of the test population. c. dose that will kill some of the test population. d. dose that will cause an infection in some of the test population. e. dose that will kill 50% of the test population. 6. Which type of antibody protects the respiratory and infant gastrointestinal tracts? a. IgA b. IgE c. IgG d. IgM 7. All of the following may be used for adherence except a. fimbriae. b. cell membrane mannose. c. glycoproteins. d. lipoproteins. e. capsules. 8. The main cells participating in antibody-mediated immunity are: a. phagocytes b. cytotoxic T cells c. macrophages d. B cells

Instructor: Renee McFarlane

  1. The mechanism by which gram-negative bacteria can cross the blood-brain barrier. a. Producing fimbriae b. Inducing endocytosis c. Producing toxins d. Inducing TNF
  2. Microbial toxins are neutralized by antibodies known as: a. agglutinins b. precipitins c. gamma globulins d. antitoxins e. None of the above.
  3. “Margination” refers to a. the adherence of phagocytes to microorganisms. b. the chemotactic response of phagocytes. c. adherence of phagocytes to the lining of blood vessels. d. dilation of blood vessels. e. the movement of phagocytes through walls of blood vessels.
  4. Which genus of bacterium contributes to plaque, cavities, gingivitis and periodontal disease? a. Streptococcus b. Staphylococcus c. Bacillus d. Escherichia e. Proteus
  5. Which endogenous molecules are specifically involved in fever induction? a. Cytokines b. Lymphokines c. Pyrogens d. Macrophages e. Interferons
  6. The stomach usually contains a very low concentration of bacteria due to a. the neutral pH b. the high pH c. the low pH d. the high turnover rate of contents e. the inhibitory actions of bile 15. Which of the following is not a mechanical factor to protect the skin and mucous membranes from infection? a. Layers of cells b. Tears c. Saliva d. Lysozyme e. Epiglottis 16. The complement system aids the host defense by a. mediating inflammation b. attracting phagocytic cells c. cytolysis d. coating antigen e. All of the above 17. Which of the following statements is true? a. Interferon is an antiviral protein. b. Interferon promotes phagocytosis. c. Interferon causes cell lysis. d. Interferon acts against specific viruses. e. Interferon attacks invading viruses. 18. The complement system acts in a ________ fashion, amplifying the response. a. synergistic b. cascade c. alternative d. classical e. mutualistic 19. Nonspecific resistance is a. the body’s ability to ward off diseases. b. the body’s defenses against any kind of pathogen. c. the body’s defense against a particular pathogen. d. the lack of resistance. e. None of the above. 20. Which DOES NOT provide long term immunity? a. Naturally acquired active immunity b. Artificially acquired active immunity c. Artificially acquired passive immunity d. All of the above

Instructor: Renee McFarlane

  1. Macrophages arise from which of the following? a. Basophil b. Eosinophil c. Lymphocyte d. Monocyte e. Neutrophil
  2. Which is true for endotoxins? a. Highly antigenic b. Found only in Gram-negative bacteria c. Usually binds to specific cellular receptors d. Highly toxic and fatal e. Toxoids are used to immunize
  3. Which of the following is involved in antibody production? a. TC b. TD c. TH d. TS
  4. Most Gram-negative bacteria have a lipopolysaccharide (LPS) which is found in the a. plasma membrane b. cell wall c. inner membrane d. outer membrane e. periplasmic space
  5. Which statement is incorrect? a. The variable region of a heavy chain binds with antigen. b. The variable regions of a light chain binds with antigen. c. The specificity of an antibody depends on the variable region. d. The constant region of a heavy chain is the same for all antibodies. e. All of the above is correct.
    1. In the figure, which areas represent antigen- binding sites? a. a and b b. a and c c. b and c d. c and d e. b and d
    2. Activation of C3a results in all of the following except a. acute inflammation. b. increased blood vessel permeability. c. fever. d. attraction of phagocytes. e. All of the above occurs when C3a is activated.
    3. Which subunit of the exotoxin is the binding portion of the molecule? a. A b. B c. C d. D e. None of the above
    4. Coagulase destroys blood clots. a. True b. False
    5. C3 is not involved in the classical pathway. a. True b. False
    6. TD regulate the immune response when no antigen is present. a. True b. False

Instructor: Renee McFarlane

  1. IL-2 stimulates maturation of TH cells. a. True b. False
  2. HIV is a virus that can causes leukocytosis. a. True b. False
  3. T cells are an example of agranulocytes. a. True b. False
  4. Gamma interferons cause neutrophils to phagocytize bacteria. a. True b. False 48. Salmonella can use antigenic variation. a. True b. False 49. Aflatoxins can be produced by Aspergillus. a. True b. False 50. Endotoxins can activate blood clotting proteins. a. True b. False

BONUS – PHAGOCYTOSIS – 3 POINTS

(PLEASE WRITE BONUS ON THE BACK OF THE SCANTRON IN THE GREEN AREA! FAILURE

TO DO SO WILL RESULT IN LOSS OF POINTS! NO EXCEPTIONS!)

Explain how Streptococcus pyogenes avoids being killed by phagocytes.